MetaADEDB 2.0 @ LMMD
Flucytosine
(XRECTZIEBJDKEO-UHFFFAOYSA-N)
Structure
SMILES
Nc1c(F)cnc(=O)[nH]1
Type(s)
Approved; Investigational
ATC code(s)
D01AE21; J02AX01
Molecular Formula:
C4H4FN3O
Molecular Weight:
129.092
Log P:
0.0724
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
2
TPSA:
71.77
CAS Number(s):
2022-85-7; 117969-88-7; 130256-61-0
Synonym(s)
1.
Flucytosine
2.
5-Fluorocytosine
3.
Alcobon
4.
Ancobon
5.
Ancotil
External Link(s)
MeSHD005437
PubChem Compound3366
BindingDB50248003
50241247
ChEBI5100
CHEMBLCHEMBL1463
DrugBankDB01099
DrugCentral1188
KEGGdr:D00323
Therapeutic Target DatabaseD0S5WG
ZINC896546
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Chest PainFAERS: 610741637CTD
OFFSIDES
SIDER
US FAERS
2CardiotoxicityFAERS: 2US FAERS
3Musculoskeletal chest painFAERS: 2US FAERS
4Bone painFAERS: 1US FAERS
5Brain DeathFAERS: 1OFFSIDES
US FAERS
6Disease ProgressionFAERS: 1US FAERS
7Drug ineffectiveFAERS: 1OFFSIDES
US FAERS
8Drug level increasedFAERS: 1US FAERS
9Ejection Fraction DecreasedFAERS: 1US FAERS
10Electrophoresis abnormalFAERS: 1US FAERS
11HypotensionFAERS: 1US FAERS
12LeukopeniaFAERS: 13303926CTD
SIDER
US FAERS
13Ventricular hypokinesiaFAERS: 1US FAERS
14nervous system disorderFAERS: 1US FAERS
15AIDS-Related Opportunistic Infections18505387CTD
16Abdominal PainSIDER
17Accidental overdoseOFFSIDES
18Acute liver damageSIDER
19Acute liver injurySIDER
20AdenocarcinomaOFFSIDES
21AgranulocytosisSIDER
22Anemia18505387CTD
23AnorexiaSIDER
24AstheniaSIDER
25AtaxiaSIDER
26Atrial Fibrillation18359968CTD
27Azotemia2392820
3303926		CTD
28BlepharoptosisOFFSIDES
29Blood creatine phosphokinase increasedOFFSIDES
30Blood creatinine increasedOFFSIDES
31Blood potassium decreasedOFFSIDES
32Blood sodiumOFFSIDES
33Blurred visionOFFSIDES
34Bone Marrow Diseases18466103CTD
35Bone marrow toxicitySIDER
36Brain AbscessOFFSIDES
37Candida serology positiveOFFSIDES
38Candidiasis, Vulvovaginal18498300
23546773		CTD
39Candidiasis

View details

2287538
2313137
10741637
15917516
 		CTD
40Cardiac ArrestSIDER
41Circumstance or information capable of leading to medication errorOFFSIDES
42Clostridium difficile toxin test positiveOFFSIDES
43CrystalluriaSIDER
44Cytokine Release SyndromeOFFSIDES
45DeafnessSIDER
46DermatitisSIDER
47Dermatomycoses18608918CTD
48Diarrhea3303926CTD
49Disseminated Intravascular CoagulationOFFSIDES
50Drug resistanceOFFSIDES
51Drug withdrawal headacheOFFSIDES
52Duodenal UlcerSIDER
53EncephalitisOFFSIDES
54EnterocolitisSIDER
55EosinophiliaSIDER
56FatigueSIDER
57Febrile NeutropeniaOFFSIDES
58Feeling abnormalSIDER
59Fungal peritonitisOFFSIDES
60Gastrointestinal PainSIDER
61Glioblastoma18398572CTD
62HeadacheSIDER
63Hepatic necrosisSIDER
64Hepatitis3303926CTD
SIDER
65HydrocephalusOFFSIDES
66HypersensitivitySIDER
67Hypoaesthesia facialOFFSIDES
68Hypokalemia18359968CTD
69Hypokinesia10741637CTD
70HypoxiaOFFSIDES
71Immune reconstitution syndromeOFFSIDES
72Incision site abscessOFFSIDES
73IncontinenceOFFSIDES
74Intraocular inflammationOFFSIDES
75Kidney Calculi2287538CTD
76Kidney Diseases1482135CTD
77Lung AbscessOFFSIDES
78Meningitis, Cryptococcal

View details

1090685
2730866
3303926
6113423
9112068
16100437
17873619
18505387
 		CTD
79Mental status changesOFFSIDES
80Metabolic acidosisOFFSIDES
81Muscle necrosisOFFSIDES
82Musculoskeletal stiffnessOFFSIDES
83Mycoses17015631CTD
84Nausea3303926CTD
SIDER
85OliguriaOFFSIDES
86Optic AtrophyOFFSIDES
87Optic Disc EdemaOFFSIDES
88PancytopeniaSIDER
89Paradoxical drug reactionOFFSIDES
90Peritonitis7566587CTD
91PleocytosisOFFSIDES
92Pneumocystis jiroveci pneumoniaOFFSIDES
93PneumothoraxOFFSIDES
94ProctocolitisSIDER
95PruritusSIDER
96Pulmonary toxicityOFFSIDES
97Radiation interactionOFFSIDES
98Renal Insufficiency18505387CTD
99Respiratory FailureOFFSIDES
100Respiratory arrestSIDER
101ScotomaOFFSIDES
102Sputum culture positiveOFFSIDES
103StridorOFFSIDES
104Thrombocytopenia3303926CTD
SIDER
105ThrombophlebitisOFFSIDES
106Toxic Epidermal NecrolysisSIDER
107UrticariaSIDER
108Ventricular Dysfunction, Left10741637CTD
109Ventricular DysfunctionSIDER
110VertigoSIDER
111Vomiting3303926CTD
SIDER
112Wound InfectionOFFSIDES
113jaundiceSIDER
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