MetaADEDB 2.0 @ LMMD
Nimodipine
(UIAGMCDKSXEBJQ-UHFFFAOYSA-N)
Structure
SMILES
COCCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1)[N+](=O)[O-])C(=O)OC(C)C)C
Type(s)
Approved; Investigational
ATC code(s)
C08CA06
Molecular Formula:
C21H26N2O7
Molecular Weight:
418.440
Log P:
3.8228
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
1
TPSA:
119.68
CAS Number(s):
66085-59-4
Synonym(s)
1.
Nimodipine
2.
Admon
3.
Bay e 9736
4.
Brainal
5.
Calnit
6.
Kenesil
7.
Modus
8.
Nimodipin Hexal
9.
Nimodipin-ISIS
10.
Nimodipino Bayvit
11.
Nimotop
12.
Nymalize
13.
Remontal
14.
Bayvit, Nimodipino
15.
Hexal, Nimodipin
16.
Nimodipin ISIS
17.
e 9736, Bay
External Link(s)
MeSHD009553
PubChem Compound4497
BindingDB50101971
ChEBI7575
CHEMBLCHEMBL1428
CHEMBL3197349
DrugBankDB00393
DrugCentral1937
IUPHAR/BPS Guide to PHARMACOLOGY2523
KEGGcpd:C07267
dr:D00438
Therapeutic Target DatabaseD0XN1F
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Incorrect route of drug administrationFAERS: 17OFFSIDES
US FAERS
2HypotensionFAERS: 11
Canada Vigilance: 2

View details

2211883
7555250
8748871
9165970
10835440
15359206
 		CTD
SIDER
Canada Vigilance
US FAERS
3BradycardiaFAERS: 97102420CTD
OFFSIDES
SIDER
US FAERS
4Medication ErrorFAERS: 8US FAERS
5Cardiac ArrestFAERS: 5US FAERS
6Circumstance or information capable of leading to medication errorFAERS: 4OFFSIDES
US FAERS
7FlushingFAERS: 4SIDER
US FAERS
8Intracranial HypotensionFAERS: 4
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
9Pharmaceutical product complaintFAERS: 4OFFSIDES
US FAERS
10Chest discomfortFAERS: 3US FAERS
11DysphasiaFAERS: 3OFFSIDES
US FAERS
12Eye painFAERS: 3US FAERS
13NervousnessFAERS: 3US FAERS
14Respiratory FailureFAERS: 3US FAERS
15RestlessnessFAERS: 3US FAERS
16Altered state of consciousnessFAERS: 2US FAERS
17Blood pressure fluctuationFAERS: 2OFFSIDES
US FAERS
18Bone painFAERS: 2OFFSIDES
US FAERS
19CardiotoxicityFAERS: 2OFFSIDES
US FAERS
20Catheter related complicationFAERS: 2OFFSIDES
US FAERS
21Cerebrovascular accidentFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
22DizzinessFAERS: 2SIDER
US FAERS
23Drug dispensing errorFAERS: 2US FAERS
24Drug effect delayedFAERS: 2US FAERS
25HeadacheFAERS: 2
Canada Vigilance: 1		17063316CTD
SIDER
Canada Vigilance
US FAERS
26NauseaFAERS: 2SIDER
US FAERS
27Post procedural complicationFAERS: 2OFFSIDES
US FAERS
28Procedural complicationFAERS: 2OFFSIDES
US FAERS
29Product label issueFAERS: 2US FAERS
30VomitingFAERS: 2SIDER
US FAERS
31Wrong technique in product usage processFAERS: 2US FAERS
32nervous system disorderFAERS: 2SIDER
US FAERS
33Angina PectorisFAERS: 1US FAERS
34Apallic syndromeFAERS: 1US FAERS
35Atrial FibrillationFAERS: 1US FAERS
36Blood alkaline phosphatase increasedFAERS: 1SIDER
US FAERS
37Chest PainFAERS: 1US FAERS
38ChillsFAERS: 1US FAERS
39Drug ineffective for unapproved indicationFAERS: 1US FAERS
40Gamma-Glutamyltransferase IncreasedFAERS: 1OFFSIDES
US FAERS
41General physical health deteriorationFAERS: 1US FAERS
42HemiparesisFAERS: 1US FAERS
43HemiplegiaFAERS: 1US FAERS
44HyperpyrexiaFAERS: 1US FAERS
45Inappropriate schedule of product administrationFAERS: 1US FAERS
46Injury associated with deviceFAERS: 1US FAERS
47Liver scan abnormalFAERS: 1US FAERS
48Mental impairmentFAERS: 1US FAERS
49Neck PainFAERS: 1US FAERS
50PalpitationsFAERS: 1SIDER
US FAERS
51Product administration errorFAERS: 1US FAERS
52Product dose omissionFAERS: 1US FAERS
53Product preparation errorFAERS: 1US FAERS
54QuadriplegiaFAERS: 1US FAERS
55Retinal Vein OcclusionFAERS: 1US FAERS
56SomnolenceFAERS: 1US FAERS
57Syringe issueFAERS: 1US FAERS
58Transaminases increasedFAERS: 1US FAERS
59Urinary RetentionFAERS: 1US FAERS
60VasospasmFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
61Accidental overdoseCanada Vigilance: 1Canada Vigilance
62AcneSIDER
63Adams-Stokes Syndrome11229238CTD
64AgraphiaOFFSIDES
65Alanine Aminotransferase IncreasedOFFSIDES
SIDER
66Amnesia2952309CTD
67Amnestic DisorderOFFSIDES
68Aneurysm, Ruptured3054619CTD
69Anticonvulsant drug level below therapeuticOFFSIDES
70Anxiety Disorders18195452CTD
71Apnea1595917CTD
72Application site burnOFFSIDES
73AsphyxiaOFFSIDES
74Ataxia22974967CTD
75Bipolar Disorder12501088CTD
76Blood alcohol increasedOFFSIDES
77Blood and lymphatic system disordersSIDER
78Blood creatine phosphokinase MB increasedOFFSIDES
79Blood lactate dehydrogenase increasedSIDER
80Brain Edema2211883CTD
81Brain Infarction3961460CTD
82Brain Ischemia

View details

2211883
2384539
3404240
6693515
7102420
15901647
 		CTD
83Bulbar palsyOFFSIDES
84Cardiomyopathies15168009CTD
85Catalepsy10368871
11143713		CTD
86Cerebral Infarction2496789CTD
87Cerebral hypoperfusionOFFSIDES
88Cerebral vasoconstrictionCanada Vigilance: 1Canada Vigilance
OFFSIDES
89Cerebrovascular Disorders7102420
11182480
17063316		CTD
90Chemical and Drug Induced Liver Injury27095094CTD
91CirrhosisOFFSIDES
92Colonic Pseudo-Obstruction3603356CTD
93CyanosisCanada Vigilance: 1Canada Vigilance
94DeafnessOFFSIDES
95Deep Vein ThrombosisSIDER
96Dementia3323259CTD
97DemyelinationOFFSIDES
98DermatitisSIDER
99Disseminated Intravascular CoagulationSIDER
100Drug ineffectiveCanada Vigilance: 1Canada Vigilance
101Dyskinesia, Drug-Induced17377417
18363098		CTD
102EncephalitisOFFSIDES
103Fever8707372CTD
104Fluid overloadOFFSIDES
105Gastric LavageOFFSIDES
106Gastric ulcerOFFSIDES
107Hepatitis B positiveOFFSIDES
108HepatitisSIDER
109Hyperalgesia23537331CTD
110HypersensitivitySIDER
111Hypoxia15359206CTD
112IleusSIDER
113Incorrect dose administeredCanada Vigilance: 1Canada Vigilance
114Intestinal ObstructionOFFSIDES
115Intracranial Aneurysm3054619CTD
OFFSIDES
116Ischemia11182480CTD
117Keratitis siccaOFFSIDES
118Kidney Diseases23428833CTD
119Lactic dehydrogenase activity increasedSIDER
120LightheadednessSIDER
121Liver Cirrhosis27095094CTD
122MeningorrhagiaOFFSIDES
123Migraine Disorders3323259CTD
124MonoparesisOFFSIDES
125Musculoskeletal discomfortSIDER
126MyalgiaSIDER
127Mycosis FungoidesOFFSIDES
128Mydriasis3038706CTD
129Necrosis2384539
11086739		CTD
130Neurotoxicity Syndromes19914363CTD
131PhlebitisSIDER
132Poor peripheral circulationOFFSIDES
133Poor quality drug administeredOFFSIDES
134Portal hypertensive gastropathyOFFSIDES
135Product packaging quantity issueCanada Vigilance: 1Canada Vigilance
136Product use in unapproved indicationCanada Vigilance: 1Canada Vigilance
137PruritusSIDER
138Respiration Disorders8163794CTD
139Ruptured cerebral aneurysmOFFSIDES
140Seizures

View details

8163794
8707372
9570719
16115668
 		CTD
141Sick Sinus Syndrome11229238CTD
142Sinus Arrest, Cardiac8061545CTD
143SinusitisOFFSIDES
144Sputum culture positiveOFFSIDES
145Status EpilepticusOFFSIDES
146Subarachnoid Hemorrhage

View details

1599066
3054619
3233859
3323259
3603356
4010871
8748871
9165970
15168009
16269628
 		CTD
147Substance Withdrawal Syndrome8707372CTD
148TachycardiaSIDER
149ThrombocytopeniaSIDER
150Tinnitus1910705CTD
151Transfusion-Related Acute Lung InjuryOFFSIDES
152Vascular Diseases3603356CTD
153Vasospasm, Intracranial3054619
3881564		CTD
154WheezingSIDER
155Wrong drug administeredOFFSIDES
156jaundiceSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120235

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.