Sevelamer
(PADGNZFOVSZIKZ-UHFFFAOYSA-N)
Structure
- SMILES
- OC(=O)O.ClCC1CO1.NCC=C
- Molecular Formula:
- C7H14ClNO4
- Molecular Weight:
- 211.643
- Log P:
- 1.6778
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 3
- TPSA:
- 96.08
- CAS Number(s):
- 845273-93-0
Synonym(s)
1.
Sevelamer
2.
GT335-012
3.
RenaGel
4.
Sevelamer Carbonate
5.
Sevelamer Hydrochloride
6.
Carbonate, Sevelamer
7.
GT335 012
8.
GT335012
9.
Hydrochloride, Sevelamer
External Link(s)
| MeSH | D000069603 |
| PubChem Compound | 11593706 49800084 |
| CHEMBL | CHEMBL1201799 |
| Therapeutic Target Database | D0G7XO |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Constipation | FAERS: 2224 | US FAERS | |
| 2 | Pruritus | FAERS: 835 | US FAERS | |
| 3 | Nausea | FAERS: 469 | US FAERS | |
| 4 | Vomiting | FAERS: 270 | US FAERS | |
| 5 | Flatulence | FAERS: 209 | US FAERS | |
| 6 | Abdominal Pain | FAERS: 154 | US FAERS | |
| 7 | Dyspepsia | FAERS: 148 | US FAERS | |
| 8 | Overdose | FAERS: 99 | US FAERS | |
| 9 | Abdominal discomfort | FAERS: 55 | US FAERS | |
| 10 | Intestinal Obstruction | FAERS: 48 | US FAERS | |
| 11 | Product use issue | FAERS: 44 | US FAERS | |
| 12 | Dizziness | FAERS: 24 | US FAERS | |
| 13 | Pneumonia | FAERS: 24 | US FAERS | |
| 14 | Arthralgia | FAERS: 19 | US FAERS | |
| 15 | Malaise | FAERS: 19 | US FAERS | |
| 16 | Crystal deposit intestine | FAERS: 18 | US FAERS | |
| 17 | Gastrointestinal motility disorder | FAERS: 18 | US FAERS | |
| 18 | Drug dose omission | FAERS: 17 | US FAERS | |
| 19 | Myocardial Infarction | FAERS: 16 | US FAERS | |
| 20 | Drug administration error | FAERS: 14 | US FAERS | |
| 21 | Gastrointestinal mucosal disorder | FAERS: 14 | US FAERS | |
| 22 | Cardiac Arrest | FAERS: 12 | US FAERS | |
| 23 | Chest Pain | FAERS: 12 | US FAERS | |
| 24 | Wrong technique in product usage process | FAERS: 12 | US FAERS | |
| 25 | Gastrointestinal hypomotility | FAERS: 11 | US FAERS | |
| 26 | Cerebrovascular accident | FAERS: 10 | US FAERS | |
| 27 | Headache | FAERS: 10 | US FAERS | |
| 28 | Colitis | FAERS: 9 | US FAERS | |
| 29 | Infection | FAERS: 9 | US FAERS | |
| 30 | Dysgeusia | FAERS: 8 | US FAERS | |
| 31 | Drug ineffective | FAERS: 7 | US FAERS | |
| 32 | Oral administration complication | FAERS: 7 | US FAERS | |
| 33 | Sepsis | FAERS: 7 | US FAERS | |
| 34 | Asthenia | FAERS: 6 | US FAERS | |
| 35 | Blood phosphorus increased | FAERS: 6 | US FAERS | |
| 36 | Choking | FAERS: 6 | US FAERS | |
| 37 | Hypotension | FAERS: 6 | US FAERS | |
| 38 | Pain | FAERS: 6 | US FAERS | |
| 39 | Wrong technique in drug usage process | FAERS: 6 | US FAERS | |
| 40 | Alopecia | FAERS: 5 | US FAERS | |
| 41 | Duodenal Ulcer | FAERS: 5 | US FAERS | |
| 42 | Gastric ulcer | FAERS: 5 | US FAERS | |
| 43 | Hypersensitivity | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 44 | Blood phosphorus abnormal | FAERS: 4 | US FAERS | |
| 45 | Burning sensation | FAERS: 4 | US FAERS | |
| 46 | Diverticulitis | FAERS: 4 | US FAERS | |
| 47 | Feeding tube user | FAERS: 4 | US FAERS | |
| 48 | Feeling abnormal | FAERS: 4 | US FAERS | |
| 49 | Gastrointestinal inflammation | FAERS: 4 | US FAERS | |
| 50 | Impaired gastric emptying | FAERS: 4 | US FAERS | |
| 51 | Incorrect route of drug administration | FAERS: 4 | US FAERS | |
| 52 | Intestinal Perforation | FAERS: 4 | US FAERS | |
| 53 | No adverse event | FAERS: 4 | US FAERS | |
| 54 | Peripheral swelling | FAERS: 4 | US FAERS | |
| 55 | Peritonitis | FAERS: 4 | US FAERS | |
| 56 | Product use in unapproved indication | FAERS: 4 | US FAERS | |
| 57 | Retching | FAERS: 4 | US FAERS | |
| 58 | Unresponsive to stimuli | FAERS: 4 | US FAERS | |
| 59 | Urticaria | FAERS: 4 | US FAERS | |
| 60 | Weight decreased | FAERS: 4 | US FAERS | |
| 61 | Acne | FAERS: 3 | US FAERS | |
| 62 | Blood potassium increased | FAERS: 3 | US FAERS | |
| 63 | Bowel movement irregularity | FAERS: 3 | US FAERS | |
| 64 | Eructation | FAERS: 3 | US FAERS | |
| 65 | Fatigue | FAERS: 3 | US FAERS | |
| 66 | Foreign body aspiration | FAERS: 3 | US FAERS | |
| 67 | Gastroenteritis | FAERS: 3 | US FAERS | |
| 68 | Incorrect dose administered | FAERS: 3 | US FAERS | |
| 69 | Large intestine perforation | FAERS: 3 | US FAERS | |
| 70 | Palpitations | FAERS: 3 | US FAERS | |
| 71 | Pancreatitis | FAERS: 3 | US FAERS | |
| 72 | Somnolence | FAERS: 3 | US FAERS | |
| 73 | Syncope | FAERS: 3 | US FAERS | |
| 74 | Thrombosis | FAERS: 3 | US FAERS | |
| 75 | Transplant | FAERS: 3 | US FAERS | |
| 76 | Unevaluable event | FAERS: 3 | US FAERS | |
| 77 | Abasia | FAERS: 2 | US FAERS | |
| 78 | Abdominal tenderness | FAERS: 2 | US FAERS | |
| 79 | Amyloidosis | FAERS: 2 | US FAERS | |
| 80 | Blood calcium abnormal | FAERS: 2 | US FAERS | |
| 81 | Blood glucose increased | FAERS: 2 | US FAERS | |
| 82 | Blood phosphorus decreased | FAERS: 2 | US FAERS | |
| 83 | Chest discomfort | FAERS: 2 | US FAERS | |
| 84 | Choking sensation | FAERS: 2 | US FAERS | |
| 85 | Clostridium difficile infection | FAERS: 2 | US FAERS | |
| 86 | Cystitis | FAERS: 2 | US FAERS | |
| 87 | Device related infection | FAERS: 2 | US FAERS | |
| 88 | Diabetes Mellitus | FAERS: 2 | US FAERS | |
| 89 | Disease Progression | FAERS: 2 | US FAERS | |
| 90 | Duodenitis | FAERS: 2 | US FAERS | |
| 91 | Dysgraphia | FAERS: 2 | US FAERS | |
| 92 | Eczema | FAERS: 2 | US FAERS | |
| 93 | Epigastric discomfort | FAERS: 2 | US FAERS | |
| 94 | General physical health deterioration | FAERS: 2 | US FAERS | |
| 95 | Hernia obstructive | FAERS: 2 | US FAERS | |
| 96 | Inappropriate schedule of drug administration | FAERS: 2 | US FAERS | |
| 97 | Inappropriate schedule of product administration | FAERS: 2 | US FAERS | |
| 98 | Influenza | FAERS: 2 | US FAERS | |
| 99 | Intentional product use issue | FAERS: 2 | US FAERS | |
| 100 | Irritable Bowel Syndrome | FAERS: 2 | US FAERS | |
| 101 | Joint stiffness | FAERS: 2 | US FAERS | |
| 102 | Joint swelling | FAERS: 2 | US FAERS | |
| 103 | Medication residue present | FAERS: 2 | US FAERS | |
| 104 | Mental status changes | FAERS: 2 | US FAERS | |
| 105 | Necrosis | FAERS: 2 | US FAERS | |
| 106 | Nephrectomy | FAERS: 2 | US FAERS | |
| 107 | Osteoporosis | FAERS: 2 | US FAERS | |
| 108 | Product formulation issue | FAERS: 2 | US FAERS | |
| 109 | Product taste abnormal | FAERS: 2 | US FAERS | |
| 110 | Product use complaint | FAERS: 2 | US FAERS | |
| 111 | Respiratory Failure | FAERS: 2 | US FAERS | |
| 112 | Serositis | FAERS: 2 | US FAERS | |
| 113 | Therapy cessation | FAERS: 2 | US FAERS | |
| 114 | Tremor | FAERS: 2 | US FAERS | |
| 115 | Urinary tract infection | FAERS: 2 | US FAERS | |
| 116 | Walking aid user | FAERS: 2 | US FAERS | |
| 117 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 118 | Alkalosis | FAERS: 1 | US FAERS | |
| 119 | Amnesia | FAERS: 1 | US FAERS | |
| 120 | Aneurysm | FAERS: 1 | US FAERS | |
| 121 | Aphagia | FAERS: 1 | US FAERS | |
| 122 | Arthritis | FAERS: 1 | US FAERS | |
| 123 | Atelectasis | FAERS: 1 | US FAERS | |
| 124 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 125 | Back Pain | FAERS: 1 | US FAERS | |
| 126 | Back disorder | FAERS: 1 | US FAERS | |
| 127 | Bacterial sepsis | FAERS: 1 | US FAERS | |
| 128 | Blood albumin decreased | FAERS: 1 | US FAERS | |
| 129 | Blood chloride abnormal | FAERS: 1 | US FAERS | |
| 130 | Blood glucose abnormal | FAERS: 1 | US FAERS | |
| 131 | Blood glucose decreased | FAERS: 1 | US FAERS | |
| 132 | Blood glucose fluctuation | FAERS: 1 | US FAERS | |
| 133 | Blood pH decreased | FAERS: 1 | US FAERS | |
| 134 | Blood potassium abnormal | FAERS: 1 | US FAERS | |
| 135 | Brain Abscess | FAERS: 1 | US FAERS | |
| 136 | Calcinosis | FAERS: 1 | US FAERS | |
| 137 | Cataract operation | FAERS: 1 | US FAERS | |
| 138 | Catheter site infection | FAERS: 1 | US FAERS | |
| 139 | Cellulitis | FAERS: 1 | US FAERS | |
| 140 | Chills | FAERS: 1 | US FAERS | |
| 141 | Clostridium difficile colitis | FAERS: 1 | US FAERS | |
| 142 | Clumsiness | FAERS: 1 | US FAERS | |
| 143 | Colon adenoma | FAERS: 1 | US FAERS | |
| 144 | Dementia | FAERS: 1 | US FAERS | |
| 145 | Dermatitis | FAERS: 1 | US FAERS | |
| 146 | Diabetic Foot | FAERS: 1 | US FAERS | |
| 147 | Diplegia | FAERS: 1 | US FAERS | |
| 148 | Diplopia | FAERS: 1 | US FAERS | |
| 149 | Disability | FAERS: 1 | US FAERS | |
| 150 | Diverticulum | FAERS: 1 | US FAERS | |
| 151 | Drug administered to patient of inappropriate age | FAERS: 1 | US FAERS | |
| 152 | Drug dispensed to wrong patient | FAERS: 1 | US FAERS | |
| 153 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 154 | Dysarthria | FAERS: 1 | US FAERS | |
| 155 | Dysuria | FAERS: 1 | US FAERS | |
| 156 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 157 | Erythema | FAERS: 1 | US FAERS | |
| 158 | Expired product administered | FAERS: 1 | US FAERS | |
| 159 | Extremity necrosis | FAERS: 1 | US FAERS | |
| 160 | Eye irritation | FAERS: 1 | US FAERS | |
| 161 | Failure to Thrive | FAERS: 1 | US FAERS | |
| 162 | Feeding tube complication | FAERS: 1 | US FAERS | |
| 163 | Feeling jittery | FAERS: 1 | US FAERS | |
| 164 | Fluid overload | FAERS: 1 | US FAERS | |
| 165 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 166 | Fracture | FAERS: 1 | US FAERS | |
| 167 | Gangrene | FAERS: 1 | US FAERS | |
| 168 | Gastric infection | FAERS: 1 | US FAERS | |
| 169 | Gastritis | FAERS: 1 | US FAERS | |
| 170 | Gastrointestinal Pain | FAERS: 1 | US FAERS | |
| 171 | Gastrointestinal gangrene | FAERS: 1 | US FAERS | |
| 172 | Gastrointestinal obstruction | FAERS: 1 | US FAERS | |
| 173 | Gastrointestinal sounds abnormal | FAERS: 1 | US FAERS | |
| 174 | Gastrointestinal ulcer | FAERS: 1 | US FAERS | |
| 175 | General physical condition abnormal | FAERS: 1 | US FAERS | |
| 176 | Granuloma | FAERS: 1 | US FAERS | |
| 177 | Hip surgery | FAERS: 1 | US FAERS | |
| 178 | Hypercapnia | FAERS: 1 | US FAERS | |
| 179 | Hyperchlorhydria | FAERS: 1 | US FAERS | |
| 180 | Incarcerated hernia | FAERS: 1 | US FAERS | |
| 181 | Incontinence | FAERS: 1 | US FAERS | |
| 182 | Infectious peritonitis | FAERS: 1 | US FAERS | |
| 183 | Inflammation | FAERS: 1 | US FAERS | |
| 184 | Intentional product misuse | FAERS: 1 | US FAERS | |
| 185 | Lethargy | FAERS: 1 | US FAERS | |
| 186 | Lip swelling | FAERS: 1 | US FAERS | |
| 187 | Malabsorption | FAERS: 1 | US FAERS | |
| 188 | Medical device complication | FAERS: 1 | US FAERS | |
| 189 | Metastatic Neoplasm | FAERS: 1 | US FAERS | |
| 190 | Musculoskeletal Pain | FAERS: 1 | US FAERS | |
| 191 | Musculoskeletal chest pain | FAERS: 1 | US FAERS | |
| 192 | Myalgia | FAERS: 1 | US FAERS | |
| 193 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 194 | Nerve injury | FAERS: 1 | US FAERS | |
| 195 | Neuralgia | FAERS: 1 | US FAERS | |
| 196 | Nonspecific reaction | FAERS: 1 | US FAERS | |
| 197 | Obesity surgery | FAERS: 1 | US FAERS | |
| 198 | Osteomyelitis | FAERS: 1 | US FAERS | |
| 199 | PCO2 abnormal | FAERS: 1 | US FAERS | |
| 200 | Parathyroidectomy | FAERS: 1 | US FAERS | |
| 201 | Parenteral Nutrition | FAERS: 1 | US FAERS | |
| 202 | Perforated ulcer | FAERS: 1 | US FAERS | |
| 203 | Peripheral venous disease | FAERS: 1 | US FAERS | |
| 204 | Pneumoconiosis | FAERS: 1 | US FAERS | |
| 205 | Poor peripheral circulation | FAERS: 1 | US FAERS | |
| 206 | Pregnancy | FAERS: 1 | US FAERS | |
| 207 | Proctitis | FAERS: 1 | US FAERS | |
| 208 | Product label issue | FAERS: 1 | US FAERS | |
| 209 | Product preparation error | FAERS: 1 | US FAERS | |
| 210 | Product size issue | FAERS: 1 | US FAERS | |
| 211 | Productive Cough | FAERS: 1 | US FAERS | |
| 212 | Pulmonary Embolism | FAERS: 1 | US FAERS | |
| 213 | Pulmonary congestion | FAERS: 1 | US FAERS | |
| 214 | Reaction to drug excipients | FAERS: 1 | US FAERS | |
| 215 | Rectal discharge | FAERS: 1 | US FAERS | |
| 216 | Rehabilitation therapy | FAERS: 1 | US FAERS | |
| 217 | Renal transplant failure | FAERS: 1 | US FAERS | |
| 218 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 219 | Scab | FAERS: 1 | US FAERS | |
| 220 | Septic Shock | FAERS: 1 | US FAERS | |
| 221 | Sneezing | FAERS: 1 | US FAERS | |
| 222 | Streptococcus test positive | FAERS: 1 | US FAERS | |
| 223 | Sudden death | FAERS: 1 | US FAERS | |
| 224 | Suicide attempt | FAERS: 1 | US FAERS | |
| 225 | Suspected counterfeit product | FAERS: 1 | US FAERS | |
| 226 | Tetany | FAERS: 1 | US FAERS | |
| 227 | Therapeutic procedure | FAERS: 1 | US FAERS | |
| 228 | Throat irritation | FAERS: 1 | US FAERS | |
| 229 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 230 | Toothache | FAERS: 1 | US FAERS | |
| 231 | Transcription medication error | FAERS: 1 | US FAERS | |
| 232 | Vascular calcification | FAERS: 1 | US FAERS | |
| 233 | Wheelchair user | FAERS: 1 | US FAERS | |
| 234 | Wound necrosis | FAERS: 1 | US FAERS | |
| 235 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 236 | Wrong schedule | FAERS: 1 | US FAERS | |
| 237 | jaundice | FAERS: 1 | US FAERS | |
| 238 | pseudomembranous colitis | FAERS: 1 | US FAERS |
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