Ferric Oxide, Saccharated
(FWZTTZUKDVJDCM-CEJAUHOTSA-M)
Structure
- SMILES
- OC[C@H]1O[C@@]([C@H]([C@@H]1O)O)(CO)O[C@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O.O.O.O.[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[OH-]
- Type(s)
- Approved
- ATC code(s)
- B03AB02; V03AE05
- Molecular Formula:
- C12H29Fe5Na2O23
- Molecular Weight:
- 866.549
- Log P:
- -6.7282
- Hydrogen Bond Acceptor:
- 15
- Hydrogen Bond Donor:
- 12
- TPSA:
- 240.28
- CAS Number(s):
- 8047-67-4
Synonym(s)
1.
Ferric Oxide, Saccharated
2.
Ferri-Saccharate
3.
Ferric Saccharate
4.
Hippiron
5.
Iron Oxide (Saccharated)
6.
Iron Sucrose
7.
Iron(III)-Hydroxide Sucrose Complex
8.
Iron-Saccharate
9.
Venofer
10.
Ferri Saccharate
11.
Iron Saccharate
12.
Saccharated Ferric Oxide
External Link(s)
| MeSH | D000077605 |
| PubChem Compound | 91663255 |
| CHEMBL | CHEMBL1200823 |
| DrugBank | DB09146 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Nausea | FAERS: 35 Canada Vigilance: 22 | Canada Vigilance US FAERS | |
| 2 | Constipation | FAERS: 31 | US FAERS | |
| 3 | Product taste abnormal | FAERS: 28 | US FAERS | |
| 4 | Abdominal discomfort | FAERS: 26 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Vomiting | FAERS: 22 Canada Vigilance: 11 | Canada Vigilance US FAERS | |
| 6 | Hypotension | FAERS: 16 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 7 | Pruritus | FAERS: 16 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 8 | Dizziness | FAERS: 15 Canada Vigilance: 15 | Canada Vigilance US FAERS | |
| 9 | Overdose | FAERS: 13 | US FAERS | |
| 10 | Abdominal Pain | FAERS: 11 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 11 | Product use in unapproved indication | FAERS: 9 | US FAERS | |
| 12 | Urticaria | FAERS: 9 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 13 | Hypersensitivity | FAERS: 7 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 14 | Bradycardia | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Blood iron increased | FAERS: 5 | US FAERS | |
| 16 | Cardiac Arrest | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 17 | Dysgeusia | FAERS: 5 | US FAERS | |
| 18 | Syncope | FAERS: 5 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 19 | Blood glucose increased | FAERS: 4 | US FAERS | |
| 20 | Cerebral Infarction | FAERS: 4 | US FAERS | |
| 21 | Transferrin saturation increased | FAERS: 4 | US FAERS | |
| 22 | Arthralgia | FAERS: 3 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 23 | Asthenia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 24 | Back Pain | FAERS: 3 Canada Vigilance: 13 | Canada Vigilance US FAERS | |
| 25 | Erythema | FAERS: 3 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 26 | Extravasation | FAERS: 3 | US FAERS | |
| 27 | Flatulence | FAERS: 3 | US FAERS | |
| 28 | Gamma-Glutamyltransferase Increased | FAERS: 3 | US FAERS | |
| 29 | Malaise | FAERS: 3 Canada Vigilance: 12 | Canada Vigilance US FAERS | |
| 30 | Myalgia | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 31 | Myocardial Infarction | FAERS: 3 | US FAERS | |
| 32 | Product physical consistency issue | FAERS: 3 | US FAERS | |
| 33 | Product physical issue | FAERS: 3 | US FAERS | |
| 34 | Restlessness | FAERS: 3 | US FAERS | |
| 35 | Tachycardia | FAERS: 3 | US FAERS | |
| 36 | Alanine Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 37 | Alopecia | FAERS: 2 | US FAERS | |
| 38 | Angioedema | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 39 | Aspartate Aminotransferase Increased | FAERS: 2 | US FAERS | |
| 40 | Blood alkaline phosphatase increased | FAERS: 2 | US FAERS | |
| 41 | Chest Pain | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 42 | Chest discomfort | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 43 | Chromaturia | FAERS: 2 | US FAERS | |
| 44 | Deep Vein Thrombosis | FAERS: 2 | US FAERS | |
| 45 | Dental caries | FAERS: 2 | US FAERS | |
| 46 | Discomfort | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 47 | Dyspepsia | FAERS: 2 | US FAERS | |
| 48 | Fatigue | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 49 | Gastrointestinal obstruction | FAERS: 2 | US FAERS | |
| 50 | Hepatitis | FAERS: 2 | US FAERS | |
| 51 | Inappropriate schedule of product administration | FAERS: 2 | US FAERS | |
| 52 | Incorrect drug administration rate | FAERS: 2 | US FAERS | |
| 53 | Infusion site pain | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 54 | Joint swelling | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 55 | Marasmus | FAERS: 2 | US FAERS | |
| 56 | Musculoskeletal Pain | FAERS: 2 | US FAERS | |
| 57 | Palpitations | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 58 | Patient dissatisfaction with treatment | FAERS: 2 | US FAERS | |
| 59 | Peripheral swelling | FAERS: 2 Canada Vigilance: 25 | Canada Vigilance US FAERS | |
| 60 | Pneumonia | FAERS: 2 | US FAERS | |
| 61 | Product supply issue | FAERS: 2 | US FAERS | |
| 62 | Restless Legs Syndrome | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 63 | Wrong technique in product usage process | FAERS: 2 | US FAERS | |
| 64 | Adverse event | FAERS: 1 | US FAERS | |
| 65 | Ageusia | FAERS: 1 | US FAERS | |
| 66 | Anal Fissure | FAERS: 1 | US FAERS | |
| 67 | Anaphylactoid Reaction | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 68 | Anisocytosis | FAERS: 1 | US FAERS | |
| 69 | Anxiety | FAERS: 1 | US FAERS | |
| 70 | Aversion | FAERS: 1 | US FAERS | |
| 71 | Burning sensation | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 72 | Chills | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 73 | Cold sweat | FAERS: 1 | US FAERS | |
| 74 | Colitis | FAERS: 1 | US FAERS | |
| 75 | Contraindicated product administered | FAERS: 1 | US FAERS | |
| 76 | Depressed Level of Consciousness | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 77 | Disorientation | FAERS: 1 | US FAERS | |
| 78 | Drug administration error | FAERS: 1 | US FAERS | |
| 79 | Drug ineffective | FAERS: 1 | US FAERS | |
| 80 | Drug level changed | FAERS: 1 | US FAERS | |
| 81 | Enterocolitis | FAERS: 1 | US FAERS | |
| 82 | Eructation | FAERS: 1 | US FAERS | |
| 83 | Extra dose administered | FAERS: 1 | US FAERS | |
| 84 | Failure to Thrive | FAERS: 1 | US FAERS | |
| 85 | Feeling Cold | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 86 | Fluid overload | FAERS: 1 | US FAERS | |
| 87 | Flushing | FAERS: 1 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 88 | Foaming at mouth | FAERS: 1 | US FAERS | |
| 89 | Gastroenteritis | FAERS: 1 | US FAERS | |
| 90 | Gastrointestinal sounds abnormal | FAERS: 1 | US FAERS | |
| 91 | Gastrointestinal stoma complication | FAERS: 1 | US FAERS | |
| 92 | General physical health deterioration | FAERS: 1 | US FAERS | |
| 93 | Glossitis | FAERS: 1 | US FAERS | |
| 94 | Hemiparesis | FAERS: 1 | US FAERS | |
| 95 | Hospice Care | FAERS: 1 | US FAERS | |
| 96 | Hypersomnia | FAERS: 1 | US FAERS | |
| 97 | Hypoxia | FAERS: 1 | US FAERS | |
| 98 | Ileus | FAERS: 1 | US FAERS | |
| 99 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 100 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 101 | Infusion Site Extravasation | FAERS: 1 | US FAERS | |
| 102 | Infusion site erythema | FAERS: 1 | US FAERS | |
| 103 | Infusion site phlebitis | FAERS: 1 | US FAERS | |
| 104 | Infusion site swelling | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 105 | Injection site extravasation | FAERS: 1 | US FAERS | |
| 106 | Intentional product use issue | FAERS: 1 | US FAERS | |
| 107 | Intestinal Obstruction | FAERS: 1 | US FAERS | |
| 108 | Joint stiffness | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 109 | Limb discomfort | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 110 | Lip swelling | FAERS: 1 | US FAERS | |
| 111 | Loss of personal independence in daily activities | FAERS: 1 | US FAERS | |
| 112 | Microcytosis | FAERS: 1 | US FAERS | |
| 113 | No adverse event | FAERS: 1 | US FAERS | |
| 114 | Oral pain | FAERS: 1 | US FAERS | |
| 115 | Pain | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 116 | Pallor | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 117 | Parathyroidectomy | FAERS: 1 | US FAERS | |
| 118 | Pemphigus | FAERS: 1 | US FAERS | |
| 119 | Peritonitis | FAERS: 1 | US FAERS | |
| 120 | Phlebitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 121 | Presyncope | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 122 | Product administration error | FAERS: 1 | US FAERS | |
| 123 | Product deposit | FAERS: 1 | US FAERS | |
| 124 | Product quality issue | FAERS: 1 | US FAERS | |
| 125 | Product substitution issue | FAERS: 1 | US FAERS | |
| 126 | Product use complaint | FAERS: 1 | US FAERS | |
| 127 | Product use issue | FAERS: 1 | US FAERS | |
| 128 | Pulmonary Embolism | FAERS: 1 | US FAERS | |
| 129 | Rectal fissure | FAERS: 1 | US FAERS | |
| 130 | Respiratory Depression | FAERS: 1 | US FAERS | |
| 131 | Retching | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 132 | Skin lesion | FAERS: 1 | US FAERS | |
| 133 | Somnolence | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 134 | Staring | FAERS: 1 | US FAERS | |
| 135 | Stomatitis | FAERS: 1 | US FAERS | |
| 136 | Stupor | FAERS: 1 | US FAERS | |
| 137 | Sudden Cardiac Death | FAERS: 1 | US FAERS | |
| 138 | Sudden death | FAERS: 1 | US FAERS | |
| 139 | Swelling | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 140 | Therapy non-responder | FAERS: 1 | US FAERS | |
| 141 | Thrombocytopenia | FAERS: 1 | US FAERS | |
| 142 | Tooth Erosion | FAERS: 1 | US FAERS | |
| 143 | Toothache | FAERS: 1 | US FAERS | |
| 144 | Tremor | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 145 | Unevaluable event | FAERS: 1 | US FAERS | |
| 146 | Unresponsive to stimuli | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 147 | Vaginal Discharge | FAERS: 1 | US FAERS | |
| 148 | Weight decreased | FAERS: 1 | US FAERS | |
| 149 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 150 | Acute kidney injury | 17699372 | CTD | |
| 151 | Altered state of consciousness | Canada Vigilance: 1 | Canada Vigilance | |
| 152 | Anemia | 11273875 20051288 | CTD | |
| 153 | Blood pressure immeasurable | Canada Vigilance: 1 | Canada Vigilance | |
| 154 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 155 | Feeling abnormal | Canada Vigilance: 2 | Canada Vigilance | |
| 156 | Flank Pain | Canada Vigilance: 2 | Canada Vigilance | |
| 157 | Gait inability | Canada Vigilance: 1 | Canada Vigilance | |
| 158 | Headache | Canada Vigilance: 2 | Canada Vigilance | |
| 159 | Inflammation | Canada Vigilance: 1 | 17699372 | CTD Canada Vigilance |
| 160 | Influenza | Canada Vigilance: 1 | Canada Vigilance | |
| 161 | Injection site pain | Canada Vigilance: 1 | Canada Vigilance | |
| 162 | Kidney Diseases | 17699372 | CTD | |
| 163 | Livedo Reticularis | Canada Vigilance: 1 | Canada Vigilance | |
| 164 | Muscle Fatigue | Canada Vigilance: 1 | Canada Vigilance | |
| 165 | Muscle tightness | Canada Vigilance: 3 | Canada Vigilance | |
| 166 | Musculoskeletal chest pain | Canada Vigilance: 2 | Canada Vigilance | |
| 167 | Musculoskeletal stiffness | Canada Vigilance: 3 | Canada Vigilance | |
| 168 | Nasopharyngitis | Canada Vigilance: 1 | Canada Vigilance | |
| 169 | Neck Pain | Canada Vigilance: 3 | Canada Vigilance | |
| 170 | Nervousness | Canada Vigilance: 1 | Canada Vigilance | |
| 171 | Oral pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 172 | Oropharyngeal pain | Canada Vigilance: 2 | Canada Vigilance | |
| 173 | Purpura | Canada Vigilance: 1 | Canada Vigilance | |
| 174 | Rash erythematous | Canada Vigilance: 1 | Canada Vigilance | |
| 175 | Respiratory arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 176 | Serum sickness-like reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 177 | Tenosynovitis | Canada Vigilance: 2 | Canada Vigilance | |
| 178 | Throat irritation | Canada Vigilance: 1 | Canada Vigilance | |
| 179 | Thrombophlebitis | Canada Vigilance: 1 | Canada Vigilance | |
| 180 | Tinnitus | Canada Vigilance: 1 | Canada Vigilance | |
| 181 | Ventricular Fibrillation | Canada Vigilance: 2 | Canada Vigilance | |
| 182 | Wheezing | Canada Vigilance: 1 | Canada Vigilance |
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