ProForma 2.0
Not calculated for this record
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-004027
P2
Aliases: P2, RW
Normalized sequence
RW
2 amino acids
Release PepDiana-V1-20260620
3
Activity records
2
Source papers
3
Positive
0
Negative / threshold
Cross-layer links
Related Integrated records
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: Not recorded
Tool: Not recorded
Calculated: Not recorded
Sequence representations
HELM 2.0
Not calculated for this record
Canonical SMILES
Not calculated for this record
Isomeric SMILES
Not calculated for this record
Paper-level observations
Experimental evidence grouped by activity
Metabolic/Cardiovascular 3 records
PMC9656729
2 observationsMetabolic/CardiovascularDPP-IV InhibitorPositive observation
Record detail Table 2: Peptide RW, Peptide Ranker Score 0.978386, PepSite2 p-value 0.01098, bound residues of α-glucosidase (5NN3): Trp376*, Asp404*, Ile441*, Trp481, Trp518, Asp518*, Asp616*, His674*.
- Measure
- other
- Value
- Not reported
- Target
- α-glucosidase
- Assay
- Not reported by source
Metabolic/CardiovascularDPP-IV InhibitorPositive observation
Record detail Table 4: Peptide RW, Peptide Ranker Score 0.978386, PepSite2 p-value 0.01257, bound residues of α-amylase (1SMD): His15, Gln41, Trp58*, Tyr62*, Arg195*, Asn298, His299*, Asp300*, Arg337.
- Measure
- other
- Value
- Not reported
- Target
- α-amylase
- Assay
- Not reported by source
PMC3133453
1 observationsMetabolic/CardiovascularACE InhibitorPositive observation
Record detail Table 2: Peptide RW, Log(1/IC50) = 4.8.
- Measure
- other
- Value
- Log(1/IC50) = 4.8
- Target
- ACE
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-004027, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00