ProForma 2.0
Not calculated for this record
Back to Primary literature
Primary-literature peptidemedium evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-003841
pep1
Aliases: pep1
Normalized sequence
LLPIVGNLLKSLL
13 amino acids
Release PepDiana-V1-20260620
4
Activity records
1
Source papers
3
Positive
1
Negative / threshold
Cross-layer links
Related Integrated records
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: Not recorded
Tool: Not recorded
Calculated: Not recorded
Sequence representations
HELM 2.0
Not calculated for this record
Canonical SMILES
Not calculated for this record
Isomeric SMILES
Not calculated for this record
Paper-level observations
Experimental evidence grouped by activity
Antimicrobial 3 records
PMC12713444
3 observationsAntimicrobialAntibacterialPositive observation
Record detail Results text: 'complete bacterial inhibition was observed at 16 μg/mL for temporin B' (free peptide). Figure 3a caption confirms planktonic growth inhibition.
- Measure
- MIC
- Value
- 16 μg/mL
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAntibacterialPositive observation
Record detail Results text: 'complete bacterial inhibition was observed at 16 μg/mL for temporin B' (peptide-loaded MSNs). Figure 3a caption confirms planktonic growth inhibition.
- Measure
- MIC
- Value
- 16 μg/mL
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
AntimicrobialAnti-BiofilmPositive observation
Record detail Results text: 'The MBEC for both peptides was determined to be 50 μg/mL, at which no viable colonies were detected after 24 h.' Figure 3c caption confirms biofilm eradication.
- Measure
- other
- Value
- 50 μg/mL (MBEC)
- Target
- Staphylococcus aureus
- Assay
- Not reported by source
Toxicity 1 records
PMC12713444
1 observationsToxicityCytotoxicNegative / threshold
Record detail Results text: 'neither free peptide nor temporin B-loaded MSNs caused significant cytotoxicity, with the cell viability exceeding 90% across all tested concentrations.' Figure 5a.
- Measure
- cell_viability
- Value
- >90%
- Target
- MRC-5
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-003841, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00