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Primary-literature peptidehigh evidence

PEPDIA-PLP-002584

RSIPTLMIFKG

Aliases: RSIPTLMIFKG

Normalized sequence

RSIPTLMIFKG

11 amino acids

Release PepDiana-V1-20260620

1

Activity records

1

Source papers

1

Positive

0

Negative / threshold

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.

Computed properties

physchem-20260620

Molecular weight

1262.5636 Da

Molecular formula

C58H99N15O14S

Theoretical pI

11.0008

Net charge at pH 7

1.7591

GRAVY

0.5091

Instability index

25.0364

Aromaticity

0.0909

Topological polar surface area

473.91 Ų

cLogP

-2.7166

Hydrogen-bond donors

17

Hydrogen-bond acceptors

17

Rotatable bonds

41

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620

ProForma 2.0

validated simple linear

RSIPTLMIFKG

HELM 2.0

validated simple linear

PEPTIDE1{R.S.I.P.T.L.M.I.F.K.G}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1CCCN1C(=O)C(NC(=O)C(CO)NC(=O)C(N)CCCNC(=N)N)C(C)CC)C(C)O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)NCC(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)CC)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O

Paper-level observations

Experimental evidence grouped by activity

Other 1 records

PMC10056772

1 observations

Citation and release provenance

Cite this identity as PepDiana record PEPDIA-PLP-002584, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.

Record updated: 2026-06-22T07:14:26.229247+00:00