ProForma 2.0
validated simple linear
RGQWTVGFNRM
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-002439
RGQWTVGFNRM
Aliases: RGQWTVGFNRM
Normalized sequence
RGQWTVGFNRM
11 amino acids
Release PepDiana-V1-20260620
1
Activity records
1
Source papers
1
Positive
0
Negative / threshold
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
1351.5357 Da
Molecular formula
C59H90N20O15S
Theoretical pI
12
Net charge at pH 7
1.7601
GRAVY
-0.8636
Instability index
-20.0091
Aromaticity
0.1818
Topological polar surface area
600.32 Ų
cLogP
-6.0669
Hydrogen-bond donors
22
Hydrogen-bond acceptors
18
Rotatable bonds
43
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{R.G.Q.W.T.V.G.F.N.R.M}$$$$V2.0
Canonical SMILES
validated
CSCCC(NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C(N)CCCNC(=N)N)C(C)O)C(C)C)C(=O)O
Isomeric SMILES
validated
CSCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)C(C)C)C(=O)O
Paper-level observations
Experimental evidence grouped by activity
Other 1 records
PMC10056772
1 observationsOtherPositive observation
Record detail Table 2: RGQWTVGFNRM, PepRank 0.71. Predicted bioactivity score from PeptideRanker.
- Measure
- other
- Value
- 0.71
- Target
- Not reported by source
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-002439, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00