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Primary-literature peptidehigh evidence

PEPDIA-PLP-001674

MAP-0403_J-2

Aliases: MAP-0403_J-2

Normalized sequence

KWLRRPWRRWRNH

13 amino acids

Release PepDiana-V1-20260620

95

Activity records

1

Source papers

78

Positive

17

Negative / threshold

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.

Computed properties

physchem-20260620

Molecular weight

1947.2605 Da

Molecular formula

C90H135N35O15

Theoretical pI

12

Net charge at pH 7

5.8462

GRAVY

-2.5846

Instability index

187.8154

Aromaticity

0.2308

Topological polar surface area

858.39 Å²

cLogP

-4.7732

Hydrogen-bond donors

34

Hydrogen-bond acceptors

22

Rotatable bonds

60

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620

ProForma 2.0

validated simple linear

KWLRRPWRRWRNH

HELM 2.0

validated simple linear

PEPTIDE1{K.W.L.R.R.P.W.R.R.W.R.N.H}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)O

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

Paper-level observations

Experimental evidence grouped by activity

Antimicrobial 92 records

PMC10653547

92 observations

AntimicrobialAntibacterialPositive observation

Table 2: E. coli ATCC 25922, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: E. coli ATCC 25922, MAP-0403 J-2 MBC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: K. pneumoniae ATCC BAA-1706, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: K. pneumoniae ATCC BAA-1706, MAP-0403 J-2 MBC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-01, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-01, MAP-0403 J-2 MBC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-02, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-02, MAP-0403 J-2 MBC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-03, MAP-0403 J-2 MIC 8 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-03, MAP-0403 J-2 MBC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-04, MAP-0403 J-2 MIC 8 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-04, MAP-0403 J-2 MBC 8 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-05, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-05, MAP-0403 J-2 MBC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 64.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-06, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-06, MAP-0403 J-2 MBC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-07, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-07, MAP-0403 J-2 MBC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-08, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-08, MAP-0403 J-2 MBC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 64.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-09, MAP-0403 J-2 MIC 8 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-09, MAP-0403 J-2 MBC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-10, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-10, MAP-0403 J-2 MBC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 64.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-01, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-01, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-02, MAP-0403 J-2 MIC 128 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 128.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-02, MAP-0403 J-2 MBC 256 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-03, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-03, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-04, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-04, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-05, MAP-0403 J-2 MIC 256 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-05, MAP-0403 J-2 MBC 512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-06, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-06, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-07, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-07, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-08, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-08, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-09, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-09, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-10, MAP-0403 J-2 MIC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialNegative / threshold

Table 2: KP-10, MAP-0403 J-2 MBC >512 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MBC
Value: >512 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 25°C control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 37°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 50°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 70°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 90°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 25°C control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 37°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 50°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 70°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 90°C, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 7 control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 2, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 4, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 6, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 8, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 10, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 7 control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 2, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 4, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 6, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 8, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 10, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 0% FBS control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 25% FBS, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 50% FBS, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 0% FBS control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 25% FBS, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 50% FBS, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, Control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 100 mM, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 150 mM, MAP-0403 J-2 MIC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 64.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 200 mM, MAP-0403 J-2 MIC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 64.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 0.5 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 1 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 2 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 1 μM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 4 μM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 8 μM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, Control, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 100 mM, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 150 mM, MAP-0403 J-2 MIC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 64.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 200 mM, MAP-0403 J-2 MIC 64 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 64.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 0.5 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 1 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 2 mM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 1 μM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 4 μM, MAP-0403 J-2 MIC 16 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 8 μM, MAP-0403 J-2 MIC 32 μg/mL

Mention PMC10653547::PEP000002PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

Toxicity 3 records

PMC10653547

3 observations

ToxicityHemolyticPositive observation

Text: MAP-0403 J-2 demonstrated negligible hemolysis even at concentrations as high as 200 μg/mL

Mention PMC10653547::PEP000002PMC10653547text

Measure: hemolysis
Value: negligible
Target: Ovis aries
Assay: Not reported by source

Source publication

ToxicityCytotoxicNegative / threshold

Text: IC50 values for MAP-0403 J-2 were >200 μg/mL against MRC-5

Mention PMC10653547::PEP000002PMC10653547text

Measure: other
Value: >200 µg/mL
Target: MRC-5
Assay: Not reported by source

Source publication

ToxicityCytotoxicPositive observation

Text: MAP-0403 J-2 reduced cell viability to 73.43% at 200 μg/mL

Mention PMC10653547::PEP000002PMC10653547text

Measure: cell_viability
Value: 73.43 %
Target: MRC-5
Assay: Not reported by source

Source publication

Citation and release provenance

Cite this identity as PepDiana record PEPDIA-PLP-001674, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.

Record updated: 2026-06-22T07:14:26.229247+00:00