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Primary-literature peptidehigh evidence

PEPDIA-PLP-001508

BP203

Aliases: BP203, BP607

Normalized sequence

KKLFKKILRYLNH

13 amino acids

Release PepDiana-V1-20260620

125

Activity records

2

Source papers

124

Positive

1

Negative / threshold

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.

Computed properties

physchem-20260620

Molecular weight

1701.1095 Da

Molecular formula

C82H137N23O16

Theoretical pI

10.5828

Net charge at pH 7

4.8423

GRAVY

-0.7231

Instability index

8.4385

Aromaticity

0.1538

Topological polar surface area

670.5 Å²

cLogP

-1.7882

Hydrogen-bond donors

24

Hydrogen-bond acceptors

22

Rotatable bonds

61

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620

ProForma 2.0

validated simple linear

KKLFKKILRYLNH

HELM 2.0

validated simple linear

PEPTIDE1{K.K.L.F.K.K.I.L.R.Y.L.N.H}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(N)CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

Paper-level observations

Experimental evidence grouped by activity

Antimicrobial 120 records

PMC10653547

92 observations

AntimicrobialAntibacterialPositive observation

Table 2: E. coli ATCC 25922, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: E. coli ATCC 25922, BP203 MBC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: K. pneumoniae ATCC BAA-1706, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: K. pneumoniae ATCC BAA-1706, BP203 MBC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-01, BP203 MIC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-01, BP203 MBC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-02, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-02, BP203 MBC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-03, BP203 MIC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-03, BP203 MBC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-04, BP203 MIC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-04, BP203 MBC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-05, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-05, BP203 MBC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-06, BP203 MIC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-06, BP203 MBC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-07, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-07, BP203 MBC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-08, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-08, BP203 MBC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-09, BP203 MIC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-09, BP203 MBC 2 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 2.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-10, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: EC-10, BP203 MBC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-01, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-01, BP203 MBC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-02, BP203 MIC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-02, BP203 MBC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-03, BP203 MIC 128 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 128.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-03, BP203 MBC 128 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 128.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-04, BP203 MIC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-04, BP203 MBC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-05, BP203 MIC 32 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 32.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-05, BP203 MBC 32 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 32.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-06, BP203 MIC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-06, BP203 MBC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-07, BP203 MIC 128 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 128.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-07, BP203 MBC 128 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 128.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-08, BP203 MIC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-08, BP203 MBC 256 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 256.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-09, BP203 MIC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-09, BP203 MBC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-10, BP203 MIC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 2: KP-10, BP203 MBC 512 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MBC
Value: 512.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 25°C control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 37°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 50°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 70°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: E. coli ATCC 25922, 90°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 25°C control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 37°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 50°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 70°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: K. pneumoniae ATCC BAA-1706, 90°C, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 7 control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 2, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 4, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 6, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 8, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: E. coli ATCC 25922, pH 10, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 7 control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 2, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 4, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 6, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 8, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 4: K. pneumoniae ATCC BAA-1706, pH 10, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 0% FBS control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 25% FBS, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: E. coli ATCC 25922, 50% FBS, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 0% FBS control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 25% FBS, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 5: K. pneumoniae ATCC BAA-1706, 50% FBS, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, Control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 100 mM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 150 mM, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, NaCl 200 mM, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 0.5 mM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 1 mM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, MgCl2 2 mM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 1 μM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 4 μM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: E. coli ATCC 25922, FeCl3 8 μM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, Control, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 100 mM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 150 mM, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, NaCl 200 mM, BP203 MIC 16 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 16.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 0.5 mM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 1 mM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, MgCl2 2 mM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 1 μM, BP203 MIC 4 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 4.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 4 μM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 6: K. pneumoniae ATCC BAA-1706, FeCl3 8 μM, BP203 MIC 8 μg/mL

Mention PMC10653547::PEP000001PMC10653547table

Measure: MIC
Value: 8.0 μg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

PMC11904594

28 observations

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 50 µg/ml against S. aureus ATCC 29213

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 50 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 50 µg/ml against S. aureus ATCC 29213

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 50 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 50 µg/ml against S. aureus MRSA USA 300

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 50 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 50 µg/ml against S. aureus MRSA USA 300

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 50 µg/mL
Target: Staphylococcus aureus
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 25 µg/ml against P. aeruginosa ATCC 27853

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 25 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 25 µg/ml against P. aeruginosa ATCC 27853

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 25 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 50 µg/ml against P. aeruginosa ST175-1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 50 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 100 µg/ml against P. aeruginosa ST175-1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 100 µg/mL
Target: Pseudomonas aeruginosa
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 3.13 µg/ml against A. baumannii ATCC 19606

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 3.13 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 6.25 µg/ml against A. baumannii ATCC 19606

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 6.25 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 25 µg/ml against A. baumannii IB010

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 25 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 50 µg/ml against A. baumannii IB010

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 50 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 6.25 µg/ml against A. baumannii Ab-1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 6.25 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 6.25 µg/ml against A. baumannii Ab-1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 6.25 µg/mL
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 12.5 µg/ml against K. pneumoniae ATCC 43816

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 12.5 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 12.5 µg/ml against K. pneumoniae ATCC 43816

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 12.5 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 12.5 µg/ml against K. pneumoniae CG258

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 12.5 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 12.5 µg/ml against K. pneumoniae CG258

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 12.5 µg/mL
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 6.25 µg/ml against E. coli ATCC 25922

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 6.25 µg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 6.25 µg/ml against E. coli ATCC 25922

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 6.25 µg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MIC 12.5 µg/ml against E. coli ESBL 1057.1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MIC
Value: 12.5 µg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Table 3: BP607 MBC 12.5 µg/ml against E. coli ESBL 1057.1

Mention PMC11904594::PEP000017PMC11904594table

Measure: MBC
Value: 12.5 µg/mL
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.3: BP607 was bactericidal at 2x MIC after 24h against K. pneumoniae CG258

Mention PMC11904594::PEP000017PMC11904594text

Measure: time_kill
Value: bactericidal at 2x MIC at 24h
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.3: all three peptides were bactericidal for E. coli ESBL 1057.1 at 6 and 24h at MIC

Mention PMC11904594::PEP000017PMC11904594text

Measure: time_kill
Value: bactericidal at MIC at 6h and 24h
Target: Escherichia coli
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.3: BP607 maintained bactericidal effect at 24h against K. pneumoniae CG258 at MIC

Mention PMC11904594::PEP000017PMC11904594text

Measure: time_kill
Value: bactericidal at MIC at 6h and 24h
Target: Klebsiella pneumoniae
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.3: none of the peptides were bactericidal for A. baumannii ATCC 19606 at 6h or 24h at MIC

Mention PMC11904594::PEP000017PMC11904594text

Measure: time_kill
Value: not bactericidal at MIC at 6h or 24h
Target: Acinetobacter baumannii
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.1: BP607 inhibited growth of all strains by ≈90% at 50 µg/ml

Mention PMC11904594::PEP000017PMC11904594text

Measure: percent_inhibition
Value: ≈90%
Target: multiple
Assay: Not reported by source

Source publication

AntimicrobialAntibacterialPositive observation

Section 3.5: BP607 was completely degraded after 10 min in human serum

Mention PMC11904594::PEP000017PMC11904594text

Measure: percent_inhibition
Value: completely degraded after 10 min
Target: Not reported by source
Assay: Not reported by source

Source publication

Toxicity 5 records

PMC10653547

3 observations

ToxicityHemolyticPositive observation

Text: BP203 demonstrated negligible hemolysis even at concentrations as high as 200 μg/mL

Mention PMC10653547::PEP000001PMC10653547text

Measure: hemolysis
Value: negligible
Target: Ovis aries
Assay: Not reported by source

Source publication

ToxicityCytotoxicNegative / threshold

Text: IC50 values for BP203 were >200 μg/mL against MRC-5

Mention PMC10653547::PEP000001PMC10653547text

Measure: other
Value: >200 µg/mL
Target: MRC-5
Assay: Not reported by source

Source publication

ToxicityCytotoxicPositive observation

Text: BP203 reduced cell viability to 56.01% at 200 μg/mL

Mention PMC10653547::PEP000001PMC10653547text

Measure: cell_viability
Value: 56.01 %
Target: MRC-5
Assay: Not reported by source

Source publication

PMC11904594

2 observations

ToxicityHemolyticPositive observation

Table 1: BP607 hemolysis 42% at 150 µM (from Oddo et al., 2016)

Mention PMC11904594::PEP000017PMC11904594table

Measure: hemolysis
Value: 42%
Target: Not reported by source
Assay: Not reported by source

Source publication

ToxicityGeneral ToxicPositive observation

Section 3.6: BP607 resulted in 80% mortality after 24h (Fig. 5B)

Mention PMC11904594::PEP000017PMC11904594text

Measure: survival_rate
Value: 80% mortality after 24h (20% survival)
Target: Galleria mellonella
Assay: Not reported by source

Source publication

Citation and release provenance

Cite this identity as PepDiana record PEPDIA-PLP-001508, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.

Record updated: 2026-06-22T07:14:26.229247+00:00