ProForma 2.0
validated simple linear
KFVVGGPQGDSGLTGRK
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-001458
KFVVGGPQGDSGLTGRK
Aliases: KFVVGGPQGDSGLTGRK
Normalized sequence
KFVVGGPQGDSGLTGRK
17 amino acids
Release PepDiana-V1-20260620
1
Activity records
1
Source papers
1
Positive
0
Negative / threshold
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
1702.9085 Da
Molecular formula
C74H123N23O23
Theoretical pI
9.9943
Net charge at pH 7
1.7592
GRAVY
-0.5529
Instability index
29.3412
Aromaticity
0.0588
Topological polar surface area
754.92 Ų
cLogP
-9.9463
Hydrogen-bond donors
26
Hydrogen-bond acceptors
25
Rotatable bonds
57
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{K.F.V.V.G.G.P.Q.G.D.S.G.L.T.G.R.K}$$$$V2.0
Canonical SMILES
validated
CC(C)CC(NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCCN)C(C)C)C(C)C)C(=O)NC(C(=O)NCC(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)O)C(C)O
Isomeric SMILES
validated
CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN)C(C)C)C(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O
Paper-level observations
Experimental evidence grouped by activity
Other 1 records
PMC10056772
1 observationsOtherPositive observation
Record detail Table 2: KFVVGGPQGDSGLTGRK, PepRank 0.58. Predicted bioactivity score from PeptideRanker.
- Measure
- other
- Value
- 0.58
- Target
- Not reported by source
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-001458, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00