ProForma 2.0
validated simple linear
KFFYGNSQVRF
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-001451
KFFYGNSQVRF
Aliases: KFFYGNSQVRF
Normalized sequence
KFFYGNSQVRF
11 amino acids
Release PepDiana-V1-20260620
1
Activity records
1
Source papers
1
Positive
0
Negative / threshold
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
1392.5593 Da
Molecular formula
C67H93N17O16
Theoretical pI
9.9943
Net charge at pH 7
1.7581
GRAVY
-0.4818
Instability index
33.9464
Aromaticity
0.3636
Topological polar surface area
568.88 Ų
cLogP
-4.2644
Hydrogen-bond donors
20
Hydrogen-bond acceptors
18
Rotatable bonds
44
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{K.F.F.Y.G.N.S.Q.V.R.F}$$$$V2.0
Canonical SMILES
validated
CC(C)C(NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccccc1)C(=O)O
Isomeric SMILES
validated
CC(C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Paper-level observations
Experimental evidence grouped by activity
Other 1 records
PMC10056772
1 observationsOtherPositive observation
Record detail Table 2: KFFYGNSQVRF, PepRank 0.68. Predicted bioactivity score from PeptideRanker.
- Measure
- other
- Value
- 0.68
- Target
- Not reported by source
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-001451, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00