ProForma 2.0
validated simple linear
IADRMQKELT
Back to Primary literature
Primary-literature peptidehigh evidence PepDiana evidence grade for a literature-derived identity; Medium indicates retained review flags, while High has no unresolved review flag.
PEPDIA-PLP-001238
P3
Aliases: P3
Normalized sequence
IADRMQKELT
10 amino acids
Release PepDiana-V1-20260620
1
Activity records
1
Source papers
0
Positive
1
Negative / threshold
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
No separate physicochemical property was reported in the primary-literature identity record. PepDiana release values are shown as computed properties.
Computed properties
physchem-20260620Molecular weight
1204.3969 Da
Molecular formula
C50H89N15O17S
Theoretical pI
6.0697
Net charge at pH 7
-0.237
GRAVY
-0.76
Instability index
-14.57
Aromaticity
0
Topological polar surface area
551.06 Ų
cLogP
-4.9952
Hydrogen-bond donors
19
Hydrogen-bond acceptors
18
Rotatable bonds
43
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{I.A.D.R.M.Q.K.E.L.T}$$$$V2.0
Canonical SMILES
validated
CCC(C)C(N)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(C(=O)O)C(C)O
Isomeric SMILES
validated
CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)O)[C@@H](C)O
Paper-level observations
Experimental evidence grouped by activity
Metabolic/Cardiovascular 1 records
PMC10001067
1 observationsMetabolic/CardiovascularXO InhibitorNegative / threshold
Record detail Table 3: XOI Activity of IC50 (mM) for IADRMQKELT is NA. Text: 'IADRMQKELT and LNSADLIK had no XOI activity at 15 mg/mL'.
- Measure
- other
- Value
- NA (no XOI activity at 15 mg/mL)
- Target
- Bos taurus
- Assay
- Not reported by source
Citation and release provenance
Cite this identity as PepDiana record PEPDIA-PLP-001238, release PepDiana-V1-20260620. Experimental observations retain their paper, mention, and activity-record identifiers.
Record updated: 2026-06-22T07:14:26.229247+00:00