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PEPDIA-INT-078209

Gold

anticancer peptide from algae protein waste (Chlorella vulgaris); Antioxidative peptide derived from algae protein waste (Chlorella vulgaris)

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

VECYGPNRPQF

Indexed sequence11 aa

1VECYGPNRPQF

Length

Molecular weight

1309.47 Da

Formula

C58H84N16O17S

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar3

Solubility proxy

Charged2

Net charge proxy +0

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1309.4494 Da

Molecular formula

C58H84N16O17S

Theoretical pI

5.9653

Net charge at pH 7

-0.2741

GRAVY

-0.9455

Instability index

69.4818

Aromaticity

0.1818

Topological polar surface area

542.35 Å²

cLogP

-5.0641

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

VECYGPNRPQF

HELM 2.0

validated simple linear

PEPTIDE1{V.E.C.Y.G.P.N.R.P.Q.F}$$$$V2.0

Canonical SMILES

validated

CC(C)C(N)C(=O)NC(CCC(=O)O)C(=O)NC(CS)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCCC1C(=O)NC(CC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(CCC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)O

Isomeric SMILES

validated

CC(C)[C@H](N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-078209,
  title = {anticancer peptide from algae protein waste (Chlorella vulgaris); Antioxidative peptide derived from algae protein waste (Chlorella vulgaris)},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-078209},
  note = {Accessed from local PepDiana development build}
}

APA-style note

anticancer peptide from algae protein waste (Chlorella vulgaris); Antioxidative peptide derived from algae protein waste (Chlorella vulgaris). (2026). PepDiana record PEPDIA-INT-078209. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-078209

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (6 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P078209_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	29.6 µM	Unknown	Cushman and Cheung (1971)	1035ahtpdb / linked
CTPDB_P078209_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	2966ahtpdb / linked
CTPDB_P078209_ACT_plantpepdb_0002	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	PPepDB_238plantpepdb / linked
CTPDB_P078209_ACT_plantpepdb_0003	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_238plantpepdb / linked
CTPDB_P078209_ACT_plantpepdb_0004	Antioxidant	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_238plantpepdb / linked
CTPDB_P078209_ACT_satpdb_0005	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb12643satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

Records

Papers

Positive

Negative

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-004098 View all experimental records

Provenance

Source database records (4)

ahtpdb

2966

Raw sequence

VECYGPNRPQF

ahtpdb

1035

Raw sequence

VECYGPNRPQF

plantpepdb

PPepDB_238

Raw sequence

VECYGPNRPQF

satpdb

satpdb12643

Raw sequence

VECYGPNRPQF

Citation trail

Literature (3 records)

Glycinyl-Histidinyl-Serine (GHS), a Novel Rapeseed Protein-Derived Peptide Has Blood Pressure-Lowering Effect in Spontaneously Hypertensive Rats

Rong He; Sunday A. Malomo; Abraham T. Girgih; Xingrong Ju; Rotimi E. Aluko

Journal of agricultural and food chemistry. 61(35): 8396-4022013PMID 23919612

Review on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins.

He HL1, Liu D, Ma CB.

Appl Biochem Biotechnol. 2013 Feb;169(3):738-49.2013PMID 23271625

-

--PMID 19916544

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.196781+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCSSCCCCTTC"
}