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PEPDIA-INT-071467

Gold

Kalata B7

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

GLPVCGETCTLGTCYTQGCTCSWPICKRN

Indexed sequence29 aa

1GLPVCGETCTLGTCYTQGCTCSWPICKRN

Length

Molecular weight

Formula

Structure type

Cyclic

Synthesis

Ribosomal

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic6

Membrane affinity proxy

Polar14

Solubility proxy

Charged3

Net charge proxy +1

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

partial sequence only structural context

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

3095.5958 Da

Molecular formula

Not calculated

Theoretical pI

7.7736

Net charge at pH 7

0.7015

GRAVY

0.0379

Instability index

49.8621

Aromaticity

0.069

Topological polar surface area

Not calculated

cLogP

Not calculated

Hydrogen-bond donors

Not calculated

Hydrogen-bond acceptors

Not calculated

Rotatable bonds

Not calculated

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

not generated modification context

Not calculated for this record

HELM 2.0

not generated modification context

Not calculated for this record

Canonical SMILES

not generated modification context

Not calculated for this record

Isomeric SMILES

not generated modification context

Not calculated for this record

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-071467,
  title = {Kalata B7},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-071467},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Kalata B7. (2026). PepDiana record PEPDIA-INT-071467. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-071467

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (38 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P071467_ACT_apd_0000	Antiparasitic	-	Not available in the current structured import	Unknown	Not reported by source	AP01054apd / linked
CTPDB_P071467_ACT_camp_0001	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ9471camp / linked
CTPDB_P071467_ACT_camp_0002	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ9471camp / linked
CTPDB_P071467_ACT_dbaasp_0003	Antimicrobial	-	20 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0004	Antimicrobial	-	40 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0005	Antimicrobial	-	>160 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0006	Antimicrobial	-	>160 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0007	Antimicrobial	-	>160 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0008	Antimicrobial	-	0.313 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0009	Antimicrobial	-	0.625 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0010	Antimicrobial	-	1.25 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0011	Antimicrobial	-	160 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0012	Antimicrobial	-	160 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0013	Antimicrobial	-	80 µM	Staphylococcus aureus ATCC 29213	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0014	Antimicrobial	-	160 µM	Staphylococcus aureus ATCC 29213	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0015	Antimicrobial	-	>160 µM	Staphylococcus aureus ATCC 29213	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0016	Antimicrobial	-	40 µM	Candida albicans ATCC 90028	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0017	Antimicrobial	-	160 µM	Candida albicans ATCC 90028	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0018	Antimicrobial	-	>160 µM	Candida albicans ATCC 90028	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0019	Antimicrobial	-	29 µM	Human histiocytic lymphoma U-937/GTB	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0020	Antimicrobial	-	6.29 µM	Haemonchus contortus	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dbaasp_0021	Antimicrobial	-	5.64 µM	Trichostrongylus colubriformis	Not reported by source	DBAASPS_5238_chain0dbaasp / linked
CTPDB_P071467_ACT_dramp_0022	Unknown	Not found	Not available in the current structured import	Unknown	Not reported by source	DRAMP00862dramp / linked
CTPDB_P071467_ACT_hemolytik_0023	Toxicity	Hemolytic	1.3 µM	Erythrocytes	Not reported by source	4159hemolytik / linked
CTPDB_P071467_ACT_plantpepdb_0024	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0025	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0026	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0027	Antiparasitic	Nematocide	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0028	Unknown	Molluscicidal	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0029	Unknown	Metal-binding	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0030	Unknown	Membrane-Binding	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0031	Antiparasitic	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0032	Toxicity	Hemolytic	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_plantpepdb_0033	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2211plantpepdb / linked
CTPDB_P071467_ACT_satpdb_0034	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb13318satpdb / linked
CTPDB_P071467_ACT_satpdb_0035	Antiparasitic	-	Not available in the current structured import	Unknown	Not reported by source	satpdb18840satpdb / linked
CTPDB_P071467_ACT_satpdb_0036	Toxicity	General Toxic	Not available in the current structured import	Unknown	Not reported by source	satpdb18840satpdb / linked
CTPDB_P071467_ACT_satpdb_0037	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb18840satpdb / linked

Provenance

Source database records (8)

apd

AP01054

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

camp

CAMPSQ9471

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

dbaasp

DBAASPS_5238_chain0

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

dramp

DRAMP00862

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

hemolytik

4159

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

plantpepdb

PPepDB_2211

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

satpdb

satpdb13318

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

satpdb

satpdb18840

Raw sequence

GLPVCGETCTLGTCYTQGCTCSWPICKRN

Citation trail

Literature (9 records)

{"reference": "J Agric Food Chem. 2008 Jul 9;56(13):5237-41", "title": "Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail).", "author": "Plan MR, Saska I, Cagauan AG, Craik DJ.2008"}

{"reference": "J Agric Food Chem. 2008 Jul 9;56(13):5237-41", "title": "Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail).", "author": "Plan MR, Saska I, Cagauan AG, Craik DJ.2008"}

-

--PMID 28669767

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis.

Plan MR, Rosengren KJ, Sando L, Daly NL, Craik DJ

Biopolymers2010PMID 20564013

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis.

Plan MR, Rosengren KJ, Sando L, Daly NL, Craik DJ

Biopolymers2010PMID 18618891

The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides.

Plan MR, Göransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ.

Chembiochem2007PMID 17534989

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.491115+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µM",
      "value": "55.2±1.3",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "source_db": "dramp",
      "assay_method": "[Ref.20564013] HD50=55.2±1.3 μM against Human red blood cells .",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Erythrocytes"
    }
  ]
}

Source metadata

[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "pdb_id": "2M9O##2JWM",
  "source_db": "dramp"
}