ProForma 2.0
not available nonstandard sequence
Not calculated for this record
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PEPDIA-INT-068734
SilverPepDiana tier derived from the internal quality score plus activity and literature coverage; it is not an external database rating.2,5-diketopiperazine 17
65
Quality PepDiana 0–100 composite of sequence, source, activity, literature, and cross-database evidence completeness.
3
Source DBs
9
Activities
3
Source refs
1
Literature
0
Patents
Integrated record
Sequence and molecular profile
VKX
Indexed sequence3 aa
1VKX
Length
3
Molecular weight
-
Formula
-
Structure type
Cyclic
Synthesis
-
Chirality
L
Family
-
Gene
-
Residue composition
V
1
K
1
X
1
Physicochemical profile
Hydrophobic1
Membrane affinity proxy
Polar0
Solubility proxy
Charged1
Net charge proxy +1
Aromatic0
Binding interaction proxy
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.
Computed properties
physchem-20260620Molecular weight
Not calculated
Molecular formula
Not calculated
Theoretical pI
Not calculated
Net charge at pH 7
Not calculated
GRAVY
Not calculated
Instability index
Not calculated
Aromaticity
Not calculated
Topological polar surface area
Not calculated
cLogP
Not calculated
Hydrogen-bond donors
Not calculated
Hydrogen-bond acceptors
Not calculated
Rotatable bonds
Not calculated
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
not available nonstandard sequence
Not calculated for this record
Canonical SMILES
not available nonstandard sequence
Not calculated for this record
Isomeric SMILES
not available nonstandard sequence
Not calculated for this record
Follow-up research
External analysis tools
Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.
Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.
Research workflow
Citation and local history
BibTeX
@misc{PEPDIA-INT-068734,
title = {2,5-diketopiperazine 17},
author = {{PepDiana Consortium}},
year = {2026},
howpublished = {PepDiana Multifunctional Peptide Database},
url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-068734},
note = {Accessed from local PepDiana development build}
}APA-style note
2,5-diketopiperazine 17. (2026). PepDiana record PEPDIA-INT-068734. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-068734
This record is saved to local recent-view history so it can reappear on the peptide browser page.
Integrated source-database annotations
Biological activity (9 records)
| Stable record | Activity | Subtype | Value | Target | Assay method | Source |
|---|---|---|---|---|---|---|
| CTPDB_P068734_ACT_dramp_0000 | Antimicrobial | - | Not available in the current structured import | Unknown | Not reported by source | DRAMP35027dramp / linked |
| CTPDB_P068734_ACT_dramp_0001 | Anticancer | - | Not available in the current structured import | Unknown | Not reported by source | DRAMP35027dramp / linked |
| CTPDB_P068734_ACT_parapep_0002 | Antiparasitic | Antiparasitic | 3.12 µM | Unknown | Microscopy | 1165parapep / linked |
| CTPDB_P068734_ACT_satpdb_0003 | Anticancer | - | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
| CTPDB_P068734_ACT_satpdb_0004 | Antimicrobial | Antibacterial | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
| CTPDB_P068734_ACT_satpdb_0005 | Antiviral | - | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
| CTPDB_P068734_ACT_satpdb_0006 | Antiparasitic | - | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
| CTPDB_P068734_ACT_satpdb_0007 | Antimicrobial | - | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
| CTPDB_P068734_ACT_satpdb_0008 | Antimicrobial | Antifungal | Not available in the current structured import | Unknown | Not reported by source | satpdb11466satpdb / linked |
Provenance
Source database records (3)
Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.
Citation trail
Literature (1 records)
Linear and cyclic dipeptides with antimalarial activity.
Pérez-Picaso L, Olivo HF, Argotte-Ramos R, Rodríguez-Gutiérrez M, Rios MY.
Audit surface
Raw annotations and release metadata
Integrated record last updated: 2026-04-15T00:59:18.893290+00:00
Modification summary
No structured modification annotations are available for this record.
Source metadata
[
{
"source_db": "dramp",
"organism_name": "Unknown"
},
{
"source_db": "parapep",
"organism_name": "Unknown"
},
{
"source_db": "satpdb",
"organism_name": "Unknown"
}
]Structure metadata
{
"source_db": "satpdb",
"dssp_states": "CCC"
}