Record tools

Copy identifiers or export this single peptide record for a local research note.

PEPDIA-INT-065287

Silver

Yunnanin C

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

GIGFYSP

Indexed sequence7 aa

1GIGFYSP

Length

Molecular weight

739.83 Da

Formula

C36H49N7O10

Structure type

Synthesis

Ribosomal

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar1

Solubility proxy

Charged0

Net charge proxy +0

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

739.815 Da

Molecular formula

C36H49N7O10

Theoretical pI

5.5243

Net charge at pH 7

-0.2409

GRAVY

0.4

Instability index

105.7871

Aromaticity

0.2857

Topological polar surface area

269.59 Å²

cLogP

-1.6945

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

GIGFYSP

HELM 2.0

validated simple linear

PEPTIDE1{G.I.G.F.Y.S.P}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)CN)C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CO)C(=O)N1CCCC1C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-065287,
  title = {Yunnanin C},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-065287},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Yunnanin C. (2026). PepDiana record PEPDIA-INT-065287. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-065287

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (3 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P065287_ACT_dbaasp_0000	Antimicrobial	-	2.2 µg/ml	Mouse lymphoma cells P388	Not reported by source	DBAASPS_20643_chain0dbaasp / linked
CTPDB_P065287_ACT_dbaasp_0001	Antimicrobial	-	2900 µM	Murine fibrosarcoma WEHI-164	Not reported by source	DBAASPS_20643_chain0dbaasp / linked
CTPDB_P065287_ACT_plantpepdb_0002	Neuroactive/Ion Channel	Toxin	Not available in the current structured import	Unknown	Not reported by source	PPepDB_2434plantpepdb / linked

Provenance

Source database records (2)

dbaasp

DBAASPS_20643_chain0

Raw sequence

GIGFYSP

plantpepdb

PPepDB_2434

Raw sequence

GIGFYSP

Citation trail

Literature (1 records)

Cyclic peptides from higher plants. 24.1 yunnanin C, a novel cyclic heptapeptide from Stellaria yunnanensis.

Morita H, Kayashita T, Shimomura M, Takeya K, Itokawa H

J Nat Prod1996PMID 8882429

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:18.424514+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µM",
      "value": "2220",
      "source_db": "dbaasp",
      "assay_method": "IC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Murine macrophage cells J774A.1"
    },
    {
      "unit": "µM",
      "value": "1610",
      "source_db": "dbaasp",
      "assay_method": "IC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human embryonic kidney HEK293 cells"
    }
  ]
}

Source metadata

[
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  }
]