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PEPDIA-INT-059562

Gold

Y-Pl1

80

Quality

3

Source DBs

7

Activities

3

Source refs

1

Literature

0

Patents

Integrated record

Sequence and molecular profile

ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY
Indexed sequence30 aa
1ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY

Length

30

Molecular weight

4094.80 Da

Formula

C203H282N50O42

Structure type

Linear

Synthesis

-

Chirality

-

Family

-

Gene

-

Residue composition

Y
8
R
5
L
4
F
3
H
2
P
2
T
2
I
2
A
1
Q
1

Physicochemical profile

Hydrophobic18

Membrane affinity proxy

Polar3

Solubility proxy

Charged7

Net charge proxy +7

Aromatic13

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

4094.7203 Da

Molecular formula

C203H282N50O42

Theoretical pI

9.9904

Net charge at pH 7

4.9622

GRAVY

-0.4333

Instability index

8.9467

Aromaticity

0.3667

Topological polar surface area

1501.89 Ų

cLogP

-2.6441

Hydrogen-bond donors

57

Hydrogen-bond acceptors

49

Rotatable bonds

120

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY

HELM 2.0

validated simple linear

PEPTIDE1{A.R.F.L.H.P.F.Q.Y.Y.T.L.Y.R.Y.L.T.R.F.L.H.R.Y.P.I.Y.Y.I.R.Y}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C1CCCN1C(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(N)=O)NC(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(Cc1c[nH]cn1)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)N)C(C)O)C(C)O)C(C)CC)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-059562,
  title = {Y-Pl1},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-059562},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Y-Pl1. (2026). PepDiana record PEPDIA-INT-059562. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-059562

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (7 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P059562_ACT_conoserver_0000Neuroactive/Ion ChannelToxinNot available in the current structured importVoltage-Gated Potassium ChannelsNot reported by sourceP05239conoserver / linked
CTPDB_P059562_ACT_kalium_0001Neuroactive/Ion ChannelIon Channel Modulator2000.0 nM[Kv1.2](https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=539)Not reported by source325kalium / linked
CTPDB_P059562_ACT_kalium_0002Neuroactive/Ion ChannelIon Channel ModulatorNot available in the current structured import[Kv1.3](https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=540)Not reported by source325kalium / linked
CTPDB_P059562_ACT_kalium_0003Neuroactive/Ion ChannelIon Channel ModulatorNot available in the current structured import[Kv1.4](https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=541)Not reported by source325kalium / linked
CTPDB_P059562_ACT_kalium_0004Neuroactive/Ion ChannelIon Channel ModulatorNot available in the current structured import[Kv1.5](https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=542)Not reported by source325kalium / linked
CTPDB_P059562_ACT_kalium_0005Neuroactive/Ion ChannelIon Channel Modulator170.0 nM[Kv1.6](https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=543)Not reported by source325kalium / linked
CTPDB_P059562_ACT_satpdb_0006ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb12139satpdb / linked

Provenance

Source database records (3)

conoserver

P05239

Raw sequence

ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY

kalium

325

Raw sequence

ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY

satpdb

satpdb12139

Raw sequence

ARFLHPFQYYTLYRYLTRFLHRYPIYYIRY

Citation trail

Literature (1 records)

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:17.112460+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata
[
  {
    "source_db": "conoserver",
    "organism_name": "Unknown"
  },
  {
    "source_db": "kalium",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "source_db": "satpdb",
  "dssp_states": "CCCSSSCSTTTHHHHHHHHHTTCSCCSCCC"
}