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PEPDIA-INT-058927

Gold

ACE inhibitor from soybean

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

PGTAVFK

Indexed sequence7 aa

1PGTAVFK

Length

Molecular weight

718.85 Da

Formula

C34H54N8O9

Structure type

Linear

Synthesis

Synthetic

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar1

Solubility proxy

Charged1

Net charge proxy +1

Aromatic1

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

718.8407 Da

Molecular formula

C34H54N8O9

Theoretical pI

9.18

Net charge at pH 7

0.9575

GRAVY

0.3143

Instability index

-25.0286

Aromaticity

0.1429

Topological polar surface area

270.18 Å²

cLogP

-2.2084

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

PGTAVFK

HELM 2.0

validated simple linear

PEPTIDE1{P.G.T.A.V.F.K}$$$$V2.0

Canonical SMILES

validated

CC(NC(=O)C(NC(=O)CNC(=O)C1CCCN1)C(C)O)C(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)O)C(C)C

Isomeric SMILES

validated

CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1)[C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-058927,
  title = {ACE inhibitor from soybean},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-058927},
  note = {Accessed from local PepDiana development build}
}

APA-style note

ACE inhibitor from soybean. (2026). PepDiana record PEPDIA-INT-058927. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-058927

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (12 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P058927_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	26.5 µM	Unknown	Not reported by source	2396ahtpdb / linked
CTPDB_P058927_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	26.5 µM	Unknown	Not reported by source	6541ahtpdb / linked
CTPDB_P058927_ACT_camp_0002	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ23415camp / linked
CTPDB_P058927_ACT_camp_0003	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ23415camp / linked
CTPDB_P058927_ACT_camp_0004	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ23415camp / linked
CTPDB_P058927_ACT_dbaasp_0005	Antimicrobial	-	31 µM	Escherichia coli ATCC 11775	Not reported by source	DBAASPS_12559_chain0dbaasp / linked
CTPDB_P058927_ACT_dbaasp_0006	Antimicrobial	-	31 µM	Staphylococcus aureus ATCC 12600	Not reported by source	DBAASPS_12559_chain0dbaasp / linked
CTPDB_P058927_ACT_dbaasp_0007	Antimicrobial	-	31 µM	Micrococcus luteus ATCC 49732	Not reported by source	DBAASPS_12559_chain0dbaasp / linked
CTPDB_P058927_ACT_dbaasp_0008	Antimicrobial	-	201 µM	Candida albicans ATCC 14053	Not reported by source	DBAASPS_12559_chain0dbaasp / linked
CTPDB_P058927_ACT_plantpepdb_0009	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	PPepDB_3797plantpepdb / linked
CTPDB_P058927_ACT_plantpepdb_0010	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	PPepDB_3797plantpepdb / linked
CTPDB_P058927_ACT_satpdb_0011	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb25609satpdb / linked

Provenance

Source database records (6)

ahtpdb

2396

Raw sequence

PGTAVFK

ahtpdb

6541

Raw sequence

PGTAVFK

camp

CAMPSQ23415

Raw sequence

PGTAVFK

dbaasp

DBAASPS_12559_chain0

Raw sequence

PGTAVFK

plantpepdb

PPepDB_3797

Raw sequence

PGTAVFK

satpdb

satpdb25609

Raw sequence

PGTAVFK

Citation trail

Literature (4 records)

A new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides.

Sagardia I1, Roa-Ureta RH, Bald C.

Food Chem. 2013 Feb 15;136(3-4):1370-6.2013PMID 23194537

A New Frontier in Soy Bioactive Peptides that May Prevent Age?related Chronic Diseases

Wenyi Wang et al.,

Comprehensive Reviews in Food Science and Food Safety. 11/2006; 4(4):63 - 78.2006

-

--PMID 24176365

-

--PMID 24508378

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.113046+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCSSCC"
}