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PEPDIA-INT-049190

Gold

Unnamed peptide

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

HPIKH

Indexed sequence5 aa

1HPIKH

Length

Molecular weight

630.75 Da

Formula

C29H46N10O6

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic1

Membrane affinity proxy

Polar0

Solubility proxy

Charged3

Net charge proxy +3

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

630.739 Da

Molecular formula

C29H46N10O6

Theoretical pI

8.7642

Net charge at pH 7

0.9335

GRAVY

-1.48

Instability index

-14.74

Aromaticity

Topological polar surface area

254.31 Å²

cLogP

-1.0496

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

HPIKH

HELM 2.0

validated simple linear

PEPTIDE1{H.P.I.K.H}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C1CCCN1C(=O)C(N)Cc1c[nH]cn1)C(=O)NC(CCCCN)C(=O)NC(Cc1c[nH]cn1)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-049190,
  title = {Unnamed peptide},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-049190},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Unnamed peptide. (2026). PepDiana record PEPDIA-INT-049190. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-049190

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (6 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P049190_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	1258.93 µM	Unknown	Not reported by source	2533ahtpdb / linked
CTPDB_P049190_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	1269.2 µM	Unknown	Not reported by source	5318ahtpdb / linked
CTPDB_P049190_ACT_ahtpdb_0002	Metabolic/Cardiovascular	ACE Inhibitor	1269.2 µM	Unknown	Cushman and Cheung (1971)	6083ahtpdb / linked
CTPDB_P049190_ACT_fermfoodb_0003	Metabolic/Cardiovascular	ACE Inhibitor	120.2 µM	Unknown	MALDITOF-MS	FermFooDB_Casein_FMDB2073fermfoodb / linked
CTPDB_P049190_ACT_fermfoodb_0004	Metabolic/Cardiovascular	ACE Inhibitor	120.2 µM	Unknown	MALDITOF-MS	FermFooDB_milk_FMDB2073fermfoodb / linked
CTPDB_P049190_ACT_satpdb_0005	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb22929satpdb / linked

Provenance

Source database records (6)

ahtpdb

2533

Raw sequence

HPIKH

ahtpdb

6083

Raw sequence

HPIKH

ahtpdb

5318

Raw sequence

HPIKH

fermfoodb

FermFooDB_Casein_FMDB2073

Raw sequence

HPIKH

fermfoodb

FermFooDB_milk_FMDB2073

Raw sequence

HPIKH

satpdb

satpdb22929

Raw sequence

HPIKH

Citation trail

Literature (3 records)

A new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides.

Sagardia I1, Roa-Ureta RH, Bald C.

Food Chem. 2013 Feb 15;136(3-4):1370-6.2013PMID 23194537

Angiotensin I-converting-enzyme-inhibitory and antibacterial peptides from Lactobacillus helveticus PR4 proteinase-hydrolyzed caseins of milk from six species

Minervini, F. et al.,

Appl Environ Microb 69 p.5297-3052003PMID 12957917

Integration of QSAR modelling and QM/MM analysis to investigate functional food peptides with antihypertensive activity

Jin Tan et al.

Molecular Simulation Volume 39, Issue 12, 20132013

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.113046+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "fermfoodb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCSCC"
}