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PEPDIA-INT-042448

Gold

Gramicidin A

85

Quality

6

Source DBs

132

Activities

23

Source refs

9

Literature

1

Patents

Integrated record

Sequence and molecular profile

VGALAVVVWLWLWLW
Indexed sequence15 aa
1VGALAVVVWLWLWLW

Length

15

Molecular weight

1811.25 Da

Formula

C96H135N19O16

Structure type

Linear

Synthesis

Non-ribosomal

Chirality

Mixed

Family

-

Gene

-

Residue composition

V
4
L
4
W
4
A
2
G
1

Physicochemical profile

Hydrophobic14

Membrane affinity proxy

Polar0

Solubility proxy

Charged0

Net charge proxy +0

Aromatic4

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1811.2164 Da

Molecular formula

C96H135N19O16

Theoretical pI

5.495

Net charge at pH 7

-0.266

GRAVY

2.1067

Instability index

70.0533

Aromaticity

0.2667

Topological polar surface area

533.88 Ų

cLogP

5.5611

Hydrogen-bond donors

20

Hydrogen-bond acceptors

16

Rotatable bonds

49

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

VGALAVVVWLWLWLW

HELM 2.0

validated simple linear

PEPTIDE1{V.G.A.L.A.V.V.V.W.L.W.L.W.L.W}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(N)C(C)C)C(=O)NC(C)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(C)C)C(C)C)C(C)C

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O)C(C)C)C(C)C)C(C)C

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-042448,
  title = {Gramicidin A},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-042448},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Gramicidin A. (2026). PepDiana record PEPDIA-INT-042448. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-042448

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (132 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P042448_ACT_apd_0000AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_apd_0001Antiviral-Not available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_apd_0002Antimicrobial-Not available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_apd_0003AntiviralAnti-HIVNot available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_apd_0004ToxicityHemolyticNot available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_apd_0005Anticancer-Not available in the current structured importUnknownNot reported by sourceAP00499apd / linked
CTPDB_P042448_ACT_camp_0006AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ2785camp / linked
CTPDB_P042448_ACT_dbaasp_0031Antimicrobial-0.0055±0.00071 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0032Antimicrobial-0.008± 0.00845 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0033Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0034Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0035Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0036Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0037Antimicrobial-0.05 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0038Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0039Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0040Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0041Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12421_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0042Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12422_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0043Antimicrobial-0.00015 ± 0.00001 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0044Antimicrobial-0.000029 ± 0.00001 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0045Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0046Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0047Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0048Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0049Antimicrobial-0.05 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0050Antimicrobial-1 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0051Antimicrobial-2 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0052Antimicrobial-1 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0053Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12423_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0054Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0055Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0056Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0057Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0058Antimicrobial->64 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0059Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0060Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0061Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0062Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12424_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0063Antimicrobial-0.010 ± 0.0 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0064Antimicrobial-0.0002 ± 0.00022 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0065Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0066Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0067Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0068Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0069Antimicrobial-0.1 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0070Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0071Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0072Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0073Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12425_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0074Antimicrobial-0.010 ± 0.0 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0075Antimicrobial-0.0002 ± 0.00022 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0076Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0077Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0078Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0079Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0080Antimicrobial-0.1 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0081Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0082Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0083Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0084Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12425_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0085Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12426_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0086Antimicrobial-0.031± 0.0085 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12426_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0087Antimicrobial-0.0265 ± 0.0064 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12426_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0088Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12426_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0089Antimicrobial-0.031± 0.0085 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12426_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0090Antimicrobial-0.0265 ± 0.0064 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12426_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0091Antimicrobial-0.0029 ± 0.0009 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0092Antimicrobial-0.0027 ± 0.0015 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0093Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0094Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0095Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0096Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0097Antimicrobial->64 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0098Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0099Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0100Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0101Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12427_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0102Antimicrobial-0.0029 ± 0.0009 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0103Antimicrobial-0.0027 ± 0.0015 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0104Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0105Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0106Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0107Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0108Antimicrobial->64 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0109Antimicrobial->64 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0110Antimicrobial->64 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0111Antimicrobial->64 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0112Antimicrobial->64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_12427_chain1dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0007Antimicrobial-NAEscherichia coli BL21Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0008Antimicrobial-2.5 µMBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0009Antimicrobial-2.5 µMStaphylococcus aureus ATCC 6538Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0010Antimicrobial-0.16 µMStreptococcus pyogenes ATCC 19615Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0011Antimicrobial->64 µg/mlEscherichia coli ATCC 25922Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0012Antimicrobial->64 µg/mlKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0013Antimicrobial->64 µg/mlProteus mirabilis ATCC 7002Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0014Antimicrobial->64 µg/mlPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0015Antimicrobial-0.05 µg/mlStreptococcus pneumoniaeNot reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0016Antimicrobial-1 µg/mlEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0017Antimicrobial-2 µg/mlEnterococcus faeciumNot reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0018Antimicrobial-0.5 µg/mlStaphylococcus epidermidis PP62ANot reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0019Antimicrobial-64 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0020Antimicrobial-0.00005±0.00001 µMPlasmodium falciparum 3D7Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0021Antimicrobial-0.000014±0.0 µMPlasmodium falciparum Dd2Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0022Antimicrobial->128 µg/mlEscherichia coli DSM 498Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0023Antimicrobial->128 µg/mlAcinetobacter calcoaceticus DSM 586Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0024Antimicrobial->128 µg/mlFranconibacter helveticus DSM 18396Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0025Antimicrobial->128 µg/mlAeromonas bestiarum DSM 13956Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0026Antimicrobial->128 µg/mlProteus myxofaciens DSM 4482Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0027Antimicrobial->128 µg/mlPseudomonas fluorescens DSM 50090Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0028Antimicrobial-1-2 µg/mlBacillus subtilis DSM 347Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0029Antimicrobial-1-2 µg/mlKocuria rhizophila DSM 348Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dbaasp_0030Antimicrobial-1-2 µg/mlMicrococcus luteus DSM 1790Not reported by sourceDBAASPS_6306_chain0dbaasp / linked
CTPDB_P042448_ACT_dramp_0113Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP00245dramp / linked
CTPDB_P042448_ACT_dramp_0114UnknownAntbacterialNot available in the current structured importUnknownNot reported by sourceDRAMP00245dramp / linked
CTPDB_P042448_ACT_dramp_0115Antiviral-Not available in the current structured importUnknownNot reported by sourceDRAMP00245dramp / linked
CTPDB_P042448_ACT_dramp_0116Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP18027dramp / linked
CTPDB_P042448_ACT_dramp_0117AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP18027dramp / linked
CTPDB_P042448_ACT_parapep_0118AntiparasiticAntiparasitic0.035 µMUnknown[3H] Hypoxanthine incorporation assay1490parapep / linked
CTPDB_P042448_ACT_parapep_0119AntiparasiticAntiparasiticNot available in the current structured importUnknownMicroscopy (Giemsa staining)1491parapep / linked
CTPDB_P042448_ACT_parapep_0120AntiparasiticAntiparasiticNot available in the current structured importUnknownMicroscopy (Giemsa staining)1652parapep / linked
CTPDB_P042448_ACT_parapep_0121AntiparasiticAntiparasiticNot available in the current structured importUnknownMicroscopy (Giemsa staining)1653parapep / linked
CTPDB_P042448_ACT_satpdb_0122Antiparasitic-Not available in the current structured importUnknownNot reported by sourcesatpdb11571satpdb / linked
CTPDB_P042448_ACT_satpdb_0123Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb11571satpdb / linked
CTPDB_P042448_ACT_satpdb_0124AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourcesatpdb17887satpdb / linked
CTPDB_P042448_ACT_satpdb_0125Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb17887satpdb / linked
CTPDB_P042448_ACT_satpdb_0126AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourcesatpdb22755satpdb / linked
CTPDB_P042448_ACT_satpdb_0127Antiviral-Not available in the current structured importUnknownNot reported by sourcesatpdb22755satpdb / linked
CTPDB_P042448_ACT_satpdb_0128ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb22755satpdb / linked
CTPDB_P042448_ACT_satpdb_0129Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb22755satpdb / linked
CTPDB_P042448_ACT_satpdb_0130Antiparasitic-Not available in the current structured importUnknownNot reported by sourcesatpdb28948satpdb / linked
CTPDB_P042448_ACT_satpdb_0131Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb28948satpdb / linked

Provenance

Source database records (23)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP00499

Raw sequence

VGAlAvVvWlWlWlW

camp

CAMPSQ2785

Raw sequence

VGALAVVVWLWLWLW

dbaasp

DBAASPS_6306_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12421_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12422_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12423_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12424_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12425_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12425_chain1

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12426_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12426_chain1

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12427_chain0

Raw sequence

VGAlAvVvWlWlWlW

dbaasp

DBAASPS_12427_chain1

Raw sequence

VGAlAvVvWlWlWlW

dramp

DRAMP00245

Raw sequence

VGALAVVVWLWLWLW

dramp

DRAMP18027

Raw sequence

VGALAVVVWLWLWLW

parapep

1490

Raw sequence

VGAlAvVvWlWlWlW

parapep

1491

Raw sequence

VGAlAvVvWlWlWlW

parapep

1652

Raw sequence

VGAlAvVvWlWlWlW

parapep

1653

Raw sequence

VGAlAvVvWlWlWlW

satpdb

satpdb11571

Raw sequence

VGAlAvVvWlWlWlW

satpdb

satpdb17887

Raw sequence

VGALAVVVWLWLWLW

satpdb

satpdb22755

Raw sequence

VGAlAvVvWlWlWLW

satpdb

satpdb28948

Raw sequence

VGAlAvVvWlWlWlW

Citation trail

Literature (9 records)

STUDIES ON A BACTERICIDAL AGENT EXTRACTED FROM A SOIL BACILLUS : III. PREPARATION AND ACTIVITY OF A PROTEIN-FREE FRACTION.

-

J Exp Med1939PMID 19870906

Solubilized gramicidin A as potential systemic antibiotics.

Wang F, Qin L, Pace CJ, Wong P, Malonis R, Gao J

Chembiochem2012PMID 22113881

Solubilized gramicidin A as potential systemic antibiotics.

Wang F, Qin L, Pace CJ, Wong P, Malonis R, Gao J

Chembiochem2012PMID 27865644

Solubilized gramicidin A as potential systemic antibiotics.

Wang F, Qin L, Pace CJ, Wong P, Malonis R, Gao J

Chembiochem2012PMID 19528287

STUDIES ON A BACTERICIDAL AGENT EXTRACTED FROM A SOIL BACILLUS : I. PREPARATION OF THE AGENT. ITS ACTIVITY IN VIT.##Macromolecular structural elucidation with solid-state NMR-derived orientational constraints.

Dubos RJ.##Ketchem RR, Lee KC, Huo S, Cross TA.

J Exp Med1939PMID 8810522

IP evidence

Patents (1)

US 7078380

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.941613+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "unit": "µM",
      "value": "5",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "40",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "60",
      "source_db": "dbaasp",
      "assay_method": "40% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "60",
      "source_db": "dbaasp",
      "assay_method": "40% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "65",
      "source_db": "dbaasp",
      "assay_method": "20% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "65",
      "source_db": "dbaasp",
      "assay_method": "20% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    }
  ]
}
Source metadata
[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "parapep",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "pdb_id": "1MAG resolved by NMR.",
  "source_db": "dramp"
}