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PEPDIA-INT-041990

Gold

conolysin-Mt2

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

FHPSLWVLIPQYIQLIRKILKS

Indexed sequence22 aa

1FHPSLWVLIPQYIQLIRKILKS

Length

Molecular weight

2693.33 Da

Formula

C132H210N32O28

Structure type

Linear

Synthesis

Chirality

Mixed

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic12

Membrane affinity proxy

Polar4

Solubility proxy

Charged4

Net charge proxy +4

Aromatic4

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

2693.277 Da

Molecular formula

C132H210N32O28

Theoretical pI

10.2897

Net charge at pH 7

2.8443

GRAVY

0.4864

Instability index

28.95

Aromaticity

0.1364

Topological polar surface area

962.12 Å²

cLogP

-1.466

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

FHPSLWVLIPQYIQLIRKILKS

HELM 2.0

validated simple linear

PEPTIDE1{F.H.P.S.L.W.V.L.I.P.Q.Y.I.Q.L.I.R.K.I.L.K.S}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)C(Cc1c[nH]cn1)NC(=O)C(N)Cc1ccccc1)C(C)C)C(C)CC)C(C)CC)C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1ccccc1)C(C)C)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-041990,
  title = {conolysin-Mt2},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-041990},
  note = {Accessed from local PepDiana development build}
}

APA-style note

conolysin-Mt2. (2026). PepDiana record PEPDIA-INT-041990. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-041990

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (4 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P041990_ACT_dramp_0000	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP02814dramp / linked
CTPDB_P041990_ACT_dramp_0001	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	DRAMP02814dramp / linked
CTPDB_P041990_ACT_satpdb_0002	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb20788satpdb / linked
CTPDB_P041990_ACT_satpdb_0003	Unknown	miscellaneous	Not available in the current structured import	Unknown	Not reported by source	satpdb21414satpdb / linked

Provenance

Source database records (4)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

conoserver

P02747

Raw sequence

FHPSLWVLIPQYIQLIRKILKS(nh2)

dramp

DRAMP02814

Raw sequence

FHPSLWVLIPQYIQLIRKILKS

satpdb

satpdb20788

Raw sequence

FHPSLWVLIPQYIQLIRKILKS

satpdb

satpdb21414

Raw sequence

FHPSLWVLIPQYIQLIRKILKS

Citation trail

Literature (1 records)

-

--PMID 17927208

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:17.184956+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "conoserver",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCSSSCSCHHHHHHHHHHHSCC"
}