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PEPDIA-INT-039136

Gold

Temporin-CDYb, Temporin-1CEb

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

ILPILSLIGGLL

Indexed sequence12 aa

1ILPILSLIGGLL

Length

Molecular weight

1221.59 Da

Formula

C60H108N12O14

Structure type

Linear

Synthesis

Ribosomal

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic8

Membrane affinity proxy

Polar1

Solubility proxy

Charged0

Net charge proxy +0

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1221.5712 Da

Molecular formula

C60H108N12O14

Theoretical pI

5.525

Net charge at pH 7

-0.2399

GRAVY

2.4417

Instability index

67.6

Aromaticity

Topological polar surface area

394.86 Å²

cLogP

0.8612

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

ILPILSLIGGLL

HELM 2.0

validated simple linear

PEPTIDE1{I.L.P.I.L.S.L.I.G.G.L.L}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(N)C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)O)C(C)CC)C(C)CC

Isomeric SMILES

validated

CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)CC)[C@@H](C)CC

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-039136,
  title = {Temporin-CDYb, Temporin-1CEb},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-039136},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Temporin-CDYb, Temporin-1CEb. (2026). PepDiana record PEPDIA-INT-039136. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-039136

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (38 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P039136_ACT_camp_0000	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ20555camp / linked
CTPDB_P039136_ACT_camp_0001	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ20555camp / linked
CTPDB_P039136_ACT_camp_0002	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ20555camp / linked
CTPDB_P039136_ACT_dbaasp_0003	Antimicrobial	-	>100 µM	Escherichia coli ATCC 11775	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0004	Antimicrobial	-	>100 µM	Staphylococcus aureus ATCC 12600	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0005	Antimicrobial	-	41 µM	Staphylococcus aureus	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0006	Antimicrobial	-	41 µM	Bacillus cereus	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0007	Antimicrobial	-	41 µM	Lactococcus lactis	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0008	Antimicrobial	-	>100 µM	Escherichia coli	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0009	Antimicrobial	-	56 µM	Human breast adenocarcinoma MCF-7	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0010	Antimicrobial	-	112 µM	Human cervical carcinoma HeLa	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0011	Antimicrobial	-	50 µM	Candida albicans CMCC 98001	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0012	Antimicrobial	-	50 µM	Streptococcus mutans CGMCC 1.2500	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0013	Antimicrobial	-	75 µM	Streptococcus salivarius CGMCC 1.2498	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0014	Antimicrobial	-	37.5 µM	Streptococcus sanguinis CGMCC 1.2497	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0015	Antimicrobial	-	37.5 µM	Lactobacillus acidophilus CGMCC 1.1854	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0016	Antimicrobial	-	75 µM	Fusobacterium nucleatum CGMCC 1.2526	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0017	Antimicrobial	-	>100 µM	Candida albicans CMCC 98001	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0018	Antimicrobial	-	>100 µM	Streptococcus mutans CGMCC 1.2500	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0019	Antimicrobial	-	>100 µM	Streptococcus salivarius CGMCC 1.2498	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0020	Antimicrobial	-	100 µM	Streptococcus sanguinis CGMCC 1.2497	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0021	Antimicrobial	-	100 µM	Lactobacillus acidophilus CGMCC 1.1854	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0022	Antimicrobial	-	>100 µM	Fusobacterium nucleatum CGMCC 1.2526	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0023	Antimicrobial	-	125 µM	Escherichia coli AS1.349	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0024	Antimicrobial	-	125 µM	Pseudomonas aeruginosa CGMCC 1.860	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0025	Antimicrobial	-	250 µM	Klebsiella aerogenes CGMCC 1.876	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0026	Antimicrobial	-	250 µM	Enterobacter cloacae CGMCC 1.58	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0027	Antimicrobial	-	175 µM	Klebsiella pneumoniae subsp. pneumoniae CGMCC 1.176	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0028	Antimicrobial	-	62.5 µM	Staphylococcus aureus AS1.72	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0029	Antimicrobial	-	62.5 µM	Bacillus cereus AS1.126	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0030	Antimicrobial	-	62.5 µM	Lactococcus lactis AS1.1690	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0031	Antimicrobial	-	125 µM	Enterococcus faecalis CGMCC 1.595	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dbaasp_0032	Antimicrobial	-	125 µM	Enterococcus faecium CGMCC 1.2334	Not reported by source	DBAASPS_3346_chain0dbaasp / linked
CTPDB_P039136_ACT_dramp_0033	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP31679dramp / linked
CTPDB_P039136_ACT_dramp_0034	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP31679dramp / linked
CTPDB_P039136_ACT_hemolytik_0035	Toxicity	Hemolytic	180.0 µM	Erythrocytes	Not reported by source	3492hemolytik / linked
CTPDB_P039136_ACT_satpdb_0036	Toxicity	General Toxic	Not available in the current structured import	Unknown	Not reported by source	satpdb26357satpdb / linked
CTPDB_P039136_ACT_satpdb_0037	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb26357satpdb / linked

Provenance

Source database records (5)

camp

CAMPSQ20555

Raw sequence

ILPILSLIGGLL

dbaasp

DBAASPS_3346_chain0

Raw sequence

ILPILSLIGGLL

dramp

DRAMP31679

Raw sequence

ILPILSLIGGLL

hemolytik

3492

Raw sequence

ILPILSLIGGLL

satpdb

satpdb26357

Raw sequence

ILPILSLIGGLL

Citation trail

Literature (4 records)

-

--PMID 25056289

-

--PMID 22348663

Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii.

Jin LL, Li Q, Song S, Feng K, Zhang DB, Wang QY, Chen YH

Comp Biochem Physiol B Biochem Mol Biol2009PMID 19539775

Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii.

Jin LL, Li Q, Song S, Feng K, Zhang DB, Wang QY, Chen YH

Comp Biochem Physiol B Biochem Mol Biol2009PMID 19341344

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:15.797023+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µM",
      "value": "180",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "source_db": "dramp",
      "assay_method": "Human erythrocytes: LD50=112 μM",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Erythrocytes"
    }
  ]
}

Source metadata

[
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCTTGGGGTSCC"
}