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PEPDIA-INT-036732

Silver

Cyclopeptide 2 (natural AMPs; sea sponge, marine animals, XXC; UCBB)

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

GPE

Indexed sequence3 aa

1GPE

Length

Molecular weight

301.30 Da

Formula

C12H19N3O6

Structure type

Synthesis

Non-ribosomal

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic0

Membrane affinity proxy

Polar0

Solubility proxy

Charged1

Net charge proxy -1

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

301.2958 Da

Molecular formula

C12H19N3O6

Theoretical pI

4.5989

Net charge at pH 7

-1.2319

GRAVY

-1.8333

Instability index

64.6

Aromaticity

Topological polar surface area

150.03 Å²

cLogP

-1.6297

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

GPE

HELM 2.0

validated simple linear

PEPTIDE1{G.P.E}$$$$V2.0

Canonical SMILES

validated

NCC(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)O

Isomeric SMILES

validated

NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-036732,
  title = {Cyclopeptide 2 (natural AMPs; sea sponge, marine animals, XXC; UCBB)},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-036732},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Cyclopeptide 2 (natural AMPs; sea sponge, marine animals, XXC; UCBB). (2026). PepDiana record PEPDIA-INT-036732. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-036732

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (7 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P036732_ACT_apd_0000	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	AP03256apd / linked
CTPDB_P036732_ACT_camp_0001	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ22947camp / linked
CTPDB_P036732_ACT_camp_0002	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ22947camp / linked
CTPDB_P036732_ACT_camp_0003	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ22947camp / linked
CTPDB_P036732_ACT_dbaasp_0004	Antimicrobial	-	50 µg/ml	Bacillus subtilis subsp. spizizenii DSM 347	Not reported by source	DBAASPS_10056_chain0dbaasp / linked
CTPDB_P036732_ACT_dbaasp_0005	Antimicrobial	-	NA	Escherichia coli DSM 498	Not reported by source	DBAASPS_10056_chain0dbaasp / linked
CTPDB_P036732_ACT_dbaasp_0006	Antimicrobial	-	NA	Saccharomyces cerevisiae DSM 70449	Not reported by source	DBAASPS_10056_chain0dbaasp / linked

Provenance

Source database records (4)

apd

AP03256

Raw sequence

GPE

b3pdb

b3pdb_1161

Raw sequence

GPE

camp

CAMPSQ22947

Raw sequence

GPE

dbaasp

DBAASPS_10056_chain0

Raw sequence

GPE

Citation trail

Literature (2 records)

Cyclic peptides from a Ruegeria strain of bacteria associated with the sponge Suberites domuncula

Mitova M, Popov S, De Rosa S. 2004

J Nat Prod2004PMID 15270577

-

--PMID 15752541

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.715308+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "b3pdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  }
]