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PEPDIA-INT-034922

Silver

Sequence 54 from Patent US 20050260715

55

Quality

2

Source DBs

5

Activities

5

Source refs

0

Literature

1

Patents

Integrated record

Sequence and molecular profile

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
Indexed sequence58 aa
1RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAED
51CMRTCGGA

Length

58

Molecular weight

6517.61 Da

Formula

C284H438N84O79S7

Structure type

-

Synthesis

-

Chirality

-

Family

-

Gene

-

Residue composition

R
6
C
6
G
6
A
6
P
4
F
4
Y
4
K
4
T
3
N
3
D
2
L
2

Physicochemical profile

Hydrophobic20

Membrane affinity proxy

Polar14

Solubility proxy

Charged14

Net charge proxy +6

Aromatic8

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

6517.4863 Da

Molecular formula

C284H438N84O79S7

Theoretical pI

9.2426

Net charge at pH 7

5.7005

GRAVY

-0.4793

Instability index

31.6657

Aromaticity

0.1379

Topological polar surface area

2645.74 Ų

cLogP

-28.2982

Hydrogen-bond donors

99

Hydrogen-bond acceptors

92

Rotatable bonds

208

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

HELM 2.0

validated simple linear

PEPTIDE1{R.P.D.F.C.L.E.P.P.Y.T.G.P.C.K.A.R.I.I.R.Y.F.Y.N.A.K.A.G.L.C.Q.T.F.V.Y.G.G.C.R.A.K.R.N.N.F.K.S.A.E.D.C.M.R.T.C.G.G.A}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CS)NC(=O)C1CCCN1C(=O)CNC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CS)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(=O)O)NC(=O)C1CCCN1C(=O)C(N)CCCNC(=N)N)C(C)O)C(=O)NC(C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CC(N)=O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CS)C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)NC(CS)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CS)C(=O)NC(CCSC)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CS)C(=O)NCC(=O)NCC(=O)NC(C)C(=O)O)C(C)O)C(C)C)C(C)O)C(C)CC

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O)[C@@H](C)CC

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-034922,
  title = {Sequence 54 from Patent US 20050260715},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-034922},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Sequence 54 from Patent US 20050260715. (2026). PepDiana record PEPDIA-INT-034922. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-034922

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (5 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P034922_ACT_dramp_0000Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP05616dramp / linked
CTPDB_P034922_ACT_thpdb_0001Clinical / Approved DrugGeneral TherapeuticNot available in the current structured importUnknownNot reported by sourceTh1158_10695_rec0thpdb / unavailable
CTPDB_P034922_ACT_thpdb_0002Clinical / Approved DrugGeneral TherapeuticNot available in the current structured importUnknownNot reported by sourceTh1158_10696_rec1thpdb / unavailable
CTPDB_P034922_ACT_thpdb_0003Clinical / Approved DrugGeneral TherapeuticNot available in the current structured importUnknownNot reported by sourceTh1158_10697_rec2thpdb / unavailable
CTPDB_P034922_ACT_thpdb_0004Clinical / Approved DrugGeneral TherapeuticNot available in the current structured importUnknownNot reported by sourceTh1158_10698_rec3thpdb / unavailable

Provenance

Source database records (5)

dramp

DRAMP05616

Raw sequence

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

thpdb

Th1158_10695_rec0

Raw sequence

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

thpdb

Th1158_10696_rec1

Raw sequence

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

thpdb

Th1158_10697_rec2

Raw sequence

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

thpdb

Th1158_10698_rec3

Raw sequence

RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA

IP evidence

Patents (1)

US 20050260715

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:19.735127+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata
[
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "thpdb",
    "organism_name": "Unknown"
  }
]