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PEPDIA-INT-034573

Gold

Sequence 54 from Patent US 20110039760

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

RRRRRRRRRR

Indexed sequence10 aa

1RRRRRRRRRR

Length

Molecular weight

1579.90 Da

Formula

C60H122N40O11

Structure type

Linear

Synthesis

Synthetic

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic0

Membrane affinity proxy

Polar0

Solubility proxy

Charged10

Net charge proxy +10

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1579.8723 Da

Molecular formula

C60H122N40O11

Theoretical pI

Net charge at pH 7

9.76

GRAVY

-4.5

Instability index

524.52

Aromaticity

Topological polar surface area

944.22 Å²

cLogP

-12.6058

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

RRRRRRRRRR

HELM 2.0

validated simple linear

PEPTIDE1{R.R.R.R.R.R.R.R.R.R}$$$$V2.0

Canonical SMILES

validated

N=C(N)NCCCC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)O

Isomeric SMILES

validated

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-034573,
  title = {Sequence 54 from Patent US 20110039760},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-034573},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Sequence 54 from Patent US 20110039760. (2026). PepDiana record PEPDIA-INT-034573. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-034573

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (34 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P034573_ACT_camp_0001	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21825camp / linked
CTPDB_P034573_ACT_camp_0002	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21825camp / linked
CTPDB_P034573_ACT_camp_0003	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21825camp / linked
CTPDB_P034573_ACT_cppsite_0004	Cell-Penetrating	CPP	Not available in the current structured import	Unknown	Not reported by source	2765cppsite / linked
CTPDB_P034573_ACT_dbaasp_0005	Antimicrobial	-	14 µg/ml	HIV-1 IIIB	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0006	Antimicrobial	-	30 µM	Bacillus subtilis ATCC 6633	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0007	Antimicrobial	-	10 µM	Listeria monocytogenes ATCC 19115	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0008	Antimicrobial	-	20 µM	Listeria monocytogenes ATCC 19115	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0009	Antimicrobial	-	30 µM	Listeria monocytogenes ATCC 19115	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0010	Antimicrobial	-	10 µM	Micrococcus luteus ATCC 9341	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0011	Antimicrobial	-	20-30 µM	Micrococcus luteus ATCC 9341	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0012	Antimicrobial	-	20 µM	Staphylococcus epidermidis ATCC 12228	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0013	Antimicrobial	-	30 µM	Staphylococcus epidermidis ATCC 12228	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0014	Antimicrobial	-	10-20 µM	Bacillus cereus ATCC 10876	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0015	Antimicrobial	-	10 µM	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0016	Antimicrobial	-	20 µM	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0017	Antimicrobial	-	30 µM	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0018	Antimicrobial	-	10 µM	Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0019	Antimicrobial	-	20 µM	Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0020	Antimicrobial	-	30 µM	Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0021	Antimicrobial	-	10 µM	Vibrio parahaemolyticus ISP 72-01	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0022	Antimicrobial	-	20 µM	Vibrio parahaemolyticus ISP 72-01	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0023	Antimicrobial	-	10 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0024	Antimicrobial	-	20-30 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0025	Antimicrobial	-	10 µM	Salmonella enterica subsp. enterica serovar Enteritidis ISP 1833-99	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0026	Antimicrobial	-	20 µM	Salmonella enterica subsp. enterica serovar Enteritidis ISP 1833-99	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0027	Antimicrobial	-	30 µM	Salmonella enterica subsp. enterica serovar Enteritidis ISP 1833-99	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0028	Antimicrobial	-	10 µM	Aeromonas hydrophila ATCC 7966	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0029	Antimicrobial	-	10 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dbaasp_0030	Antimicrobial	-	20-30 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_6586_chain0dbaasp / linked
CTPDB_P034573_ACT_dramp_0031	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP09865dramp / linked
CTPDB_P034573_ACT_hipdb_0000	Antiviral	Anti-HIV	0.014 mg/mL	HIV	Not reported by source	HIPdb_HIP1041hipdb / unavailable
CTPDB_P034573_ACT_satpdb_0032	Antiviral	-	Not available in the current structured import	Unknown	Not reported by source	satpdb20738satpdb / linked
CTPDB_P034573_ACT_satpdb_0033	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb20738satpdb / linked

Provenance

Source database records (6)

hipdb

HIPdb_HIP1041

Raw sequence

RRRRRRRRRR

camp

CAMPSQ21825

Raw sequence

RRRRRRRRRR

cppsite

2765

Raw sequence

RRRRRRRRRR

dbaasp

DBAASPS_6586_chain0

Raw sequence

RRRRRRRRRR

dramp

DRAMP09865

Raw sequence

RRRRRRRRRR

satpdb

satpdb20738

Raw sequence

RRRRRRRRRR

Citation trail

Literature (5 records)

{"pubmed_id": "22319541.0", "paper": "Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat.", "authors": "Keogan S, Passic S, Krebs FC.", "reference": "Int J Pept. 2012;2012:349427. Epub 2012 Jan 29."}

{"pubmed_id": "22319541.0", "paper": "Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat.", "authors": "Keogan S, Passic S, Krebs FC.", "reference": "Int J Pept. 2012;2012:349427. Epub 2012 Jan 29."}

IP evidence

Patents (1)

US 20110039760

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:13.602083+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "hipdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "cppsite",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CTHHHHTTCC"
}