Record tools

Copy identifiers or export this single peptide record for a local research note.

PEPDIA-INT-028075

Gold

Antimicrobial peptide (LLKK)2

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

LLKKLLKK

Indexed sequence8 aa

1LLKKLLKK

Length

Molecular weight

983.36 Da

Formula

C48H94N12O9

Structure type

Linear

Synthesis

Synthetic

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic4

Membrane affinity proxy

Polar0

Solubility proxy

Charged4

Net charge proxy +4

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

983.3349 Da

Molecular formula

C48H94N12O9

Theoretical pI

10.4777

Net charge at pH 7

3.7561

GRAVY

-0.05

Instability index

-23.0875

Aromaticity

Topological polar surface area

371.1 Å²

cLogP

0.4923

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

LLKKLLKK

HELM 2.0

validated simple linear

PEPTIDE1{L.L.K.K.L.L.K.K}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(N)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-028075,
  title = {Antimicrobial peptide (LLKK)2},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-028075},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Antimicrobial peptide (LLKK)2. (2026). PepDiana record PEPDIA-INT-028075. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-028075

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (30 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P028075_ACT_camp_0000	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ17504camp / linked
CTPDB_P028075_ACT_camp_0001	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ17504camp / linked
CTPDB_P028075_ACT_camp_0002	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ20337camp / linked
CTPDB_P028075_ACT_dbaasp_0009	Antimicrobial	-	8 µg/ml	Bacillus subtilis ATCC 23857	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0010	Antimicrobial	-	>500 µg/ml	Staphylococcus aureus ATCC 29737	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0011	Antimicrobial	-	31 µg/ml	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0012	Antimicrobial	-	125 µg/ml	Klebsiella aerogenes ATCC 13048	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0013	Antimicrobial	-	8 µg/ml	Pseudomonas aeruginosa ATCC 9027	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0014	Antimicrobial	-	63 µg/ml	Candida albicans ATCC 10231	Not reported by source	DBAASPS_14954_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0015	Antimicrobial	-	16 µg/ml	Bacillus subtilis ATCC 23857	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0016	Antimicrobial	-	400 µg/ml	Staphylococcus aureus ATCC 29737	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0017	Antimicrobial	-	16 µg/ml	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0018	Antimicrobial	-	63 µg/ml	Klebsiella aerogenes ATCC 13048	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0019	Antimicrobial	-	8 µg/ml	Pseudomonas aeruginosa ATCC 9027	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0020	Antimicrobial	-	125 µg/ml	Candida albicans ATCC 10231	Not reported by source	DBAASPS_14956_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0021	Antimicrobial	-	16 µg/ml	Bacillus subtilis ATCC 23857	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0022	Antimicrobial	-	400 µg/ml	Staphylococcus aureus ATCC 29737	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0023	Antimicrobial	-	16 µg/ml	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0024	Antimicrobial	-	63 µg/ml	Klebsiella aerogenes ATCC 13048	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0025	Antimicrobial	-	8 µg/ml	Pseudomonas aeruginosa ATCC 9027	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0026	Antimicrobial	-	125 µg/ml	Candida albicans ATCC 10231	Not reported by source	DBAASPS_14956_chain1dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0003	Antimicrobial	-	500 µg/ml	Bacillus subtilis ATCC 23857	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0004	Antimicrobial	-	250-500 µg/ml	Candida albicans ATCC 10231	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0005	Antimicrobial	-	125 µg/ml	Mycobacterium smegmatis ATCC 14468	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0006	Antimicrobial	-	500 µg/ml	Mycobacterium bovis BCG	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0007	Antimicrobial	-	>500 µg/ml	Mycobacterium tuberculosis H37Rv	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_dbaasp_0008	Antimicrobial	-	>500 µg/ml	Mycobacterium tuberculosis CSU87	Not reported by source	DBAASPS_3095_chain0dbaasp / linked
CTPDB_P028075_ACT_hemolytik_0027	Toxicity	Hemolytic	500.0 mg/L	Erythrocytes	Not reported by source	2047hemolytik / linked
CTPDB_P028075_ACT_satpdb_0028	Toxicity	General Toxic	Not available in the current structured import	Unknown	Not reported by source	satpdb20637satpdb / linked
CTPDB_P028075_ACT_satpdb_0029	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb20637satpdb / linked

Provenance

Source database records (9)

camp

CAMPSQ17504

Raw sequence

LLKKLLKK

camp

CAMPSQ20337

Raw sequence

LLKKLLKK

dbaasp

DBAASPS_3095_chain0

Raw sequence

LLKKLLKK

dbaasp

DBAASPS_14951_chain0

Raw sequence

LLKKLLKK

dbaasp

DBAASPS_14954_chain0

Raw sequence

LLKKLLKK

dbaasp

DBAASPS_14956_chain0

Raw sequence

LLKKLLKK

dbaasp

DBAASPS_14956_chain1

Raw sequence

LLKKLLKK

hemolytik

2047

Raw sequence

LLKKLLKK

satpdb

satpdb20637

Raw sequence

LLKKLLKK

Citation trail

Literature (5 records)

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:15.432864+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µg/ml",
      "value": ">500",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": ">1000",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Rat erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": ">500",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": ">500",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": ">500",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    }
  ]
}

Source metadata

[
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CHHHHHCC"
}