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PEPDIA-INT-026117

Gold

Salmon Calcitonin

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

Indexed sequence32 aa

1CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

Length

Molecular weight

3434.91 Da

Formula

C145H241N43O49S2

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic7

Membrane affinity proxy

Polar15

Solubility proxy

Charged5

Net charge proxy +3

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

3434.8535 Da

Molecular formula

C145H241N43O49S2

Theoretical pI

8.8598

Net charge at pH 7

1.8273

GRAVY

-0.5375

Instability index

17.8406

Aromaticity

0.0313

Topological polar surface area

1502.42 Å²

cLogP

-21.465

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

112

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

HELM 2.0

validated simple linear

PEPTIDE1{C.S.N.L.S.T.C.V.L.G.K.L.S.Q.E.L.H.K.L.Q.T.Y.P.R.T.N.T.G.S.G.T.P}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CS)NC(=O)C(NC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(N)CS)C(C)O)C(C)C)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NCC(=O)NC(CO)C(=O)NCC(=O)NC(C(=O)N1CCCC1C(=O)O)C(C)O)C(C)O)C(C)O)C(C)O

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CS)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-026117,
  title = {Salmon Calcitonin},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-026117},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Salmon Calcitonin. (2026). PepDiana record PEPDIA-INT-026117. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-026117

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (19 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P026117_ACT_thpdb_0000	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10098_rec0thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0001	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10099_rec1thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0002	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10100_rec2thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0003	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10101_rec3thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0004	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10102_rec4thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0005	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10103_rec5thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0006	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10104_rec6thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0007	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10105_rec7thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0008	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10106_rec8thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0009	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10107_rec9thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0010	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10108_rec10thpdb / unavailable
CTPDB_P026117_ACT_thpdb_0011	Clinical / Approved Drug	General Therapeutic	Not available in the current structured import	Unknown	Not reported by source	Th1014_10109_rec11thpdb / unavailable
CTPDB_P026117_ACT_topicalpdb_0012	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Cumulative amounts 0.67 ± 0.10 mg/cm2 and fluxes 0.67 ± 0.10 mg/cm2·h; Vertical Franz diffusion cell, HPLC; in vitro	1080topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0013	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Cumulative amounts 0.33 ± 0.09 mg/cm2 and fluxes 0.11 ± 0.03 mg/cm2·h; Vertical Franz diffusion cell, HPLC; in vitro	1081topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0014	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Cumulative amounts 0.26 ± 0.02 mg/cm2 and fluxes 0.04 ± 0.00 mg/cm2·h; Vertical Franz diffusion cell, HPLC; in vitro	1082topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0015	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Area Under the Curve0–120 min (ng·min/ml)=19.8±2.9 , Absolute Bioavailability (%)=33.2 , Relative Bioavailability (%)=68.6; Radioimmunoassay; in vivo	1226topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0016	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Area Under the Curve0–120 min (ng·min/ml)=43.0±5.0 , Absolute Bioavailability (%)=37.0 , Relative Bioavailability (%)=76.5; Radioimmunoassay; in vivo	1227topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0017	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Area Under the Curve0–120 min (ng·min/ml)=72.2±7.3 , Absolute Bioavailability (%)=32.5 , Relative Bioavailability (%)=67.2; Radioimmunoassay; in vivo	1228topicalpdb / linked
CTPDB_P026117_ACT_topicalpdb_0018	Wound Healing	Skin Penetrating	Not available in the current structured import	Unknown	Iontophoretic patches delivered SCT at an average infusion rate of 177.9±58.7 ng/(min kg) and an average steady state concentration of 7.58±1.35 ng/ml was achieved.; ELISA, noncompartmental analysis using WinNonlin; in vivo	1606topicalpdb / linked

Provenance

Source database records (19)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

thpdb

Th1014_10098_rec0

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10099_rec1

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10100_rec2

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10101_rec3

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10102_rec4

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10103_rec5

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10104_rec6

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10105_rec7

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10106_rec8

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10107_rec9

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10108_rec10

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

thpdb

Th1014_10109_rec11

Raw sequence

CSNLSTCVLGKLSQELHKLQTYPRTNTGSGTP

topicalpdb

1080

Raw sequence

CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP

topicalpdb

1081

Raw sequence

CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP

topicalpdb

1082

Raw sequence

CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP

topicalpdb

1226

Raw sequence

CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP

topicalpdb

1227

Raw sequence

CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP

topicalpdb

1228

Raw sequence

CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP

topicalpdb

1606

Raw sequence

CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP

Citation trail

Literature (3 records)

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:22.023514+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    },
    {
      "source_db": "thpdb",
      "assay_method": "It is devoid of embryotoxic, teratogenic and mutagenic potential.",
      "toxicity_type": "Toxicity"
    }
  ]
}

Source metadata

[
  {
    "source_db": "thpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "topicalpdb",
    "organism_name": "Unknown"
  }
]