Record tools

Copy identifiers or export this single peptide record for a local research note.

PEPDIA-INT-024143

Silver

Gageotetrin C

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

ELLL

Indexed sequence4 aa

1ELLL

Length

Molecular weight

486.61 Da

Formula

C23H42N4O7

Structure type

Synthesis

Non-ribosomal

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar0

Solubility proxy

Charged1

Net charge proxy -1

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

486.6021 Da

Molecular formula

C23H42N4O7

Theoretical pI

4.05

Net charge at pH 7

-1.1632

GRAVY

1.975

Instability index

7.5

Aromaticity

Topological polar surface area

187.92 Å²

cLogP

0.8558

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

ELLL

HELM 2.0

validated simple linear

PEPTIDE1{E.L.L.L}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(N)CCC(=O)O)C(=O)O

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(=O)O)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-024143,
  title = {Gageotetrin C},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-024143},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Gageotetrin C. (2026). PepDiana record PEPDIA-INT-024143. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-024143

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (20 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P024143_ACT_apd_0000	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	AP02382apd / linked
CTPDB_P024143_ACT_apd_0001	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	AP02382apd / linked
CTPDB_P024143_ACT_camp_0002	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21286camp / linked
CTPDB_P024143_ACT_camp_0003	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21286camp / linked
CTPDB_P024143_ACT_camp_0004	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ21286camp / linked
CTPDB_P024143_ACT_dbaasp_0019	Antimicrobial	-	31 µg/ml	Mycoplasma hyorhinis ATCC 17981	Not reported by source	DBAASPS_21416_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0005	Antimicrobial	-	0.04 µM	Staphylococcus aureus	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0006	Antimicrobial	-	0.04 µM	Bacillus subtilis	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0007	Antimicrobial	-	0.02 µM	Salmonella enterica subsp. enterica serovar Typhi	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0008	Antimicrobial	-	0.02 µM	Pseudomonas aeruginosa	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0009	Antimicrobial	-	0.02 µM	Rhizoctonia solani	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0010	Antimicrobial	-	0.02 µM	Colletotrichum acutatum	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0011	Antimicrobial	-	0.01 µM	Botrytis cinerea	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0012	Antimicrobial	-	0.11 µM	Phytophthora capsici	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0013	Antimicrobial	-	NA	Human breast adenocarcinoma MDA-MB-231	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0014	Antimicrobial	-	NA	Human colon adenocarcinoma HCT-15	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0015	Antimicrobial	-	NA	Human prostate adenocarcinoma PC-3	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0016	Antimicrobial	-	NA	Human lung adenocarcinoma NCI-H23	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0017	Antimicrobial	-	NA	Human gastric cancer NUGC-3	Not reported by source	DBAASPS_5514_chain0dbaasp / linked
CTPDB_P024143_ACT_dbaasp_0018	Antimicrobial	-	NA	Human renal adenocarcinoma ACHN	Not reported by source	DBAASPS_5514_chain0dbaasp / linked

Provenance

Source database records (4)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP02382

Raw sequence

ELLL

camp

CAMPSQ21286

Raw sequence

ELLL

dbaasp

DBAASPS_5514_chain0

Raw sequence

ELLL

dbaasp

DBAASPS_21416_chain0

Raw sequence

ELlL

Citation trail

Literature (2 records)

Gageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis.

Tareq FS, Lee MA, Lee HS, Lee YJ, Lee JS, Hasan CM, Islam MT, Shin HJ.2014

Org Lett2014PMID 24502521

Anti-Mycoplasma Activity of Bacilotetrins C-E, Cyclic Lipodepsipeptides from the Marine-Derived Bacillus subtilis and Structure Revision of Bacilotetrins A and B

Lee HS, Shin HJ

Mar Drugs2021PMID 34677427

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:12.494831+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  }
]