Record tools

Copy identifiers or export this single peptide record for a local research note.

PEPDIA-INT-022550

Silver

caspase 3 inhibitor

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

DEVD

Indexed sequence4 aa

1DEVD

Length

Molecular weight

476.44 Da

Formula

C18H28N4O11

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic1

Membrane affinity proxy

Polar0

Solubility proxy

Charged3

Net charge proxy -3

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

476.4351 Da

Molecular formula

C18H28N4O11

Theoretical pI

4.05

Net charge at pH 7

-3.2317

GRAVY

-1.575

Instability index

-30.075

Aromaticity

Topological polar surface area

262.52 Å²

cLogP

-2.6771

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

DEVD

HELM 2.0

validated simple linear

PEPTIDE1{D.E.V.D}$$$$V2.0

Canonical SMILES

validated

CC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(N)CC(=O)O)C(=O)NC(CC(=O)O)C(=O)O

Isomeric SMILES

validated

CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-022550,
  title = {caspase 3 inhibitor},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-022550},
  note = {Accessed from local PepDiana development build}
}

APA-style note

caspase 3 inhibitor. (2026). PepDiana record PEPDIA-INT-022550. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-022550

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (6 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P022550_ACT_cancerppd_0000	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	2872cancerppd / linked
CTPDB_P022550_ACT_cancerppd_0001	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	2873cancerppd / linked
CTPDB_P022550_ACT_cancerppd_0002	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	2874cancerppd / linked
CTPDB_P022550_ACT_dramp_0003	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP35103dramp / linked
CTPDB_P022550_ACT_dramp_0004	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP35103dramp / linked
CTPDB_P022550_ACT_satpdb_0005	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	satpdb14243satpdb / linked

Provenance

Source database records (5)

cancerppd

2872

Raw sequence

DEVD

cancerppd

2873

Raw sequence

DEVD

cancerppd

2874

Raw sequence

DEVD

dramp

DRAMP35103

Raw sequence

DEVD

satpdb

satpdb14243

Raw sequence

DEVD

Citation trail

Literature (1 records)

-

--PMID 23583573

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:16.851167+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "cancerppd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCC"
}