ProForma 2.0
validated simple linear
CS
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PEPDIA-INT-017908
SilverPepDiana tier derived from the internal quality score plus activity and literature coverage; it is not an external database rating.SLAY-screened peptide P3257
65
Quality PepDiana 0–100 composite of sequence, source, activity, literature, and cross-database evidence completeness.
3
Source DBs
5
Activities
4
Source refs
2
Literature
0
Patents
Integrated record
Sequence and molecular profile
CS
Indexed sequence2 aa
1CS
Length
2
Molecular weight
208.24 Da
Formula
C6H12N2O4S
Structure type
Linear
Synthesis
-
Chirality
-
Family
-
Gene
-
Residue composition
C
1
S
1
Physicochemical profile
Hydrophobic0
Membrane affinity proxy
Polar2
Solubility proxy
Charged0
Net charge proxy +0
Aromatic0
Binding interaction proxy
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.
Computed properties
physchem-20260620Molecular weight
208.2355 Da
Molecular formula
C6H12N2O4S
Theoretical pI
5.5181
Net charge at pH 7
-0.2498
GRAVY
0.85
Instability index
5
Aromaticity
0
Topological polar surface area
112.65 Ų
cLogP
-2.1948
Hydrogen-bond donors
5
Hydrogen-bond acceptors
5
Rotatable bonds
5
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{C.S}$$$$V2.0
Canonical SMILES
validated
NC(CS)C(=O)NC(CO)C(=O)O
Isomeric SMILES
validated
N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)O
Follow-up research
External analysis tools
Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.
Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.
Research workflow
Citation and local history
BibTeX
@misc{PEPDIA-INT-017908,
title = {SLAY-screened peptide P3257},
author = {{PepDiana Consortium}},
year = {2026},
howpublished = {PepDiana Multifunctional Peptide Database},
url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-017908},
note = {Accessed from local PepDiana development build}
}APA-style note
SLAY-screened peptide P3257. (2026). PepDiana record PEPDIA-INT-017908. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-017908
This record is saved to local recent-view history so it can reappear on the peptide browser page.
Integrated source-database annotations
Biological activity (5 records)
| Stable record | Activity | Subtype | Value | Target | Assay method | Source |
|---|---|---|---|---|---|---|
| CTPDB_P017908_ACT_avpdb_0000 | Antiviral | General Antiviral | Low | Influenza A virus | Luciferase assay | AVPdb_AVP1158avpdb / unavailable |
| CTPDB_P017908_ACT_dramp_0001 | Antimicrobial | Anti-Gram- | Not available in the current structured import | Unknown | Not reported by source | DRAMP24907dramp / linked |
| CTPDB_P017908_ACT_dramp_0002 | Antimicrobial | Anti-Gram- | Not available in the current structured import | Unknown | Not reported by source | DRAMP25527dramp / linked |
| CTPDB_P017908_ACT_satpdb_0003 | Antiviral | - | Not available in the current structured import | Unknown | Not reported by source | satpdb20217satpdb / linked |
| CTPDB_P017908_ACT_satpdb_0004 | Antimicrobial | - | Not available in the current structured import | Unknown | Not reported by source | satpdb20217satpdb / linked |
Provenance
Source database records (4)
Citation trail
Literature (2 records)
Inhibition of influenza virus replication by constrained peptides targeting nucleoprotein.
Jiang H, Xu Y, Li L, Weng L, Wang Q, Zhang S, Jia B, Hu H, He Y, Jacob Y, Toyoda T.
Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries
Ashley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies
Audit surface
Raw annotations and release metadata
Integrated record last updated: 2026-04-15T00:59:13.225027+00:00
Modification summary
No structured modification annotations are available for this record.
Source metadata
[
{
"source_db": "avpdb",
"organism_name": "Unknown"
},
{
"source_db": "dramp",
"organism_name": "Unknown"
},
{
"source_db": "satpdb",
"organism_name": "Unknown"
}
]Structure metadata
{
"source_db": "satpdb",
"dssp_states": "CC"
}