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PEPDIA-INT-014966

Gold

Unnamed peptide

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

VVPPA

Indexed sequence5 aa

1VVPPA

Length

Molecular weight

481.59 Da

Formula

C23H39N5O6

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar0

Solubility proxy

Charged0

Net charge proxy +0

Aromatic0

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

481.5856 Da

Molecular formula

C23H39N5O6

Theoretical pI

5.495

Net charge at pH 7

-0.266

GRAVY

1.4

Instability index

123.56

Aromaticity

Topological polar surface area

162.14 Å²

cLogP

-0.3182

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

VVPPA

HELM 2.0

validated simple linear

PEPTIDE1{V.V.P.P.A}$$$$V2.0

Canonical SMILES

validated

CC(NC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(NC(=O)C(N)C(C)C)C(C)C)C(=O)O

Isomeric SMILES

validated

CC(C)[C@H](N)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)C(C)C

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-014966,
  title = {Unnamed peptide},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-014966},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Unnamed peptide. (2026). PepDiana record PEPDIA-INT-014966. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-014966

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (5 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P014966_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	79.5 µM	Unknown	Cushman and Cheung (1971)	1034ahtpdb / linked
CTPDB_P014966_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	79.5 µM	Unknown	Cushman and Cheung (1971)	1865ahtpdb / linked
CTPDB_P014966_ACT_ahtpdb_0002	Metabolic/Cardiovascular	ACE Inhibitor	79.43 µM	Unknown	Not reported by source	2435ahtpdb / linked
CTPDB_P014966_ACT_plantpepdb_0003	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	PPepDB_225plantpepdb / linked
CTPDB_P014966_ACT_satpdb_0004	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb15950satpdb / linked

Provenance

Source database records (5)

ahtpdb

2435

Raw sequence

VVPPA

ahtpdb

1034

Raw sequence

VVPPA

ahtpdb

1865

Raw sequence

VVPPA

plantpepdb

PPepDB_225

Raw sequence

VVPPA

satpdb

satpdb15950

Raw sequence

VVPPA

Citation trail

Literature (3 records)

A new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides.

Sagardia I1, Roa-Ureta RH, Bald C.

Food Chem. 2013 Feb 15;136(3-4):1370-6.2013PMID 23194537

Review on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins.

He HL1, Liu D, Ma CB.

Appl Biochem Biotechnol. 2013 Feb;169(3):738-49.2013PMID 23271625

Vegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities.

M C García, P Puchalska, C Esteve, M L Marina

Talanta 03/2013; 106C:328-349.2013PMID 23598136

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.113046+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCCC"
}