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PEPDIA-INT-013822

Bronze

Chrysophsin-1 (1-21)

45

Quality

1

Source DBs

0

Activities

1

Source refs

1

Literature

0

Patents

Integrated record

Sequence and molecular profile

FFGWLIKGAIHAGKAIHGLIH
Indexed sequence21 aa
1FFGWLIKGAIHAGKAIHGLIH

Length

21

Molecular weight

2286.76 Da

Formula

C112H168N30O22

Structure type

-

Synthesis

Synthetic

Chirality

-

Family

-

Gene

-

Residue composition

G
4
I
4
A
3
H
3
F
2
L
2
K
2
W
1

Physicochemical profile

Hydrophobic12

Membrane affinity proxy

Polar0

Solubility proxy

Charged5

Net charge proxy +5

Aromatic6

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

2286.7198 Da

Molecular formula

C112H168N30O22

Theoretical pI

10.003

Net charge at pH 7

2.0196

GRAVY

0.7952

Instability index

17.7952

Aromaticity

0.1429

Topological polar surface area

799.19 Ų

cLogP

-1.679

Hydrogen-bond donors

28

Hydrogen-bond acceptors

27

Rotatable bonds

73

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

FFGWLIKGAIHAGKAIHGLIH

HELM 2.0

validated simple linear

PEPTIDE1{F.F.G.W.L.I.K.G.A.I.H.A.G.K.A.I.H.G.L.I.H}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)CNC(=O)C(C)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(N)Cc1ccccc1)C(C)CC)C(C)CC)C(=O)NC(Cc1c[nH]cn1)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(Cc1c[nH]cn1)C(=O)O)C(C)CC

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O)[C@@H](C)CC

Follow-up research

External analysis tools

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-013822,
  title = {Chrysophsin-1 (1-21)},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-013822},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Chrysophsin-1 (1-21). (2026). PepDiana record PEPDIA-INT-013822. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-013822

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Provenance

Source database records (1)

dbaasp

DBAASPS_5198_chain0

Raw sequence

FFGWLIKGAIHAGKAIHGLIH

Citation trail

Literature (1 records)

Membrane interaction of chrysophsin-1, a histidine-rich antimicrobial peptide from red sea bream.

Mason AJ, Bertani P, Moulay G, Marquette A, Perrone B, Drake AF, Kichler A, Bechinger B

Biochemistry2007PMID 18052076

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:17.895670+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "unit": "µM",
      "value": "20.5",
      "source_db": "dbaasp",
      "assay_method": "EC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human fibroblasts MRC-5"
    },
    {
      "unit": "µM",
      "value": "34.8",
      "source_db": "dbaasp",
      "assay_method": "EC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human fibroblasts MRC-5"
    },
    {
      "unit": "µM",
      "value": "17.3",
      "source_db": "dbaasp",
      "assay_method": "EC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human fibroblasts MRC-5 SV2"
    },
    {
      "unit": "µM",
      "value": "28.1",
      "source_db": "dbaasp",
      "assay_method": "EC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human fibroblasts MRC-5 SV2"
    }
  ]
}
Source metadata
[
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  }
]