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PEPDIA-INT-012878

Gold

Unnamed peptide

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

AKYSY

Indexed sequence5 aa

1AKYSY

Length

Molecular weight

630.70 Da

Formula

C30H42N6O9

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic3

Membrane affinity proxy

Polar1

Solubility proxy

Charged1

Net charge proxy +1

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

630.6892 Da

Molecular formula

C30H42N6O9

Theoretical pI

8.5409

Net charge at pH 7

0.7929

GRAVY

-1.1

Instability index

Aromaticity

0.4

Topological polar surface area

266.43 Å²

cLogP

-1.6247

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

AKYSY

HELM 2.0

validated simple linear

PEPTIDE1{A.K.Y.S.Y}$$$$V2.0

Canonical SMILES

validated

CC(N)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CO)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

Isomeric SMILES

validated

C[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

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Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-012878,
  title = {Unnamed peptide},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-012878},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Unnamed peptide. (2026). PepDiana record PEPDIA-INT-012878. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-012878

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (6 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P012878_ACT_ahtpdb_0001	Metabolic/Cardiovascular	ACE Inhibitor	1.5 µM	Unknown	Not reported by source	2308ahtpdb / linked
CTPDB_P012878_ACT_ahtpdb_0000	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	4260ahtpdb / linked
CTPDB_P012878_ACT_ahtpdb_0002	Metabolic/Cardiovascular	ACE Inhibitor	Not available for this observation	Unknown	Not reported by source	5008ahtpdb / linked
CTPDB_P012878_ACT_ahtpdb_0003	Metabolic/Cardiovascular	ACE Inhibitor	1.5 µM	Unknown	Not reported by source	6676ahtpdb / linked
CTPDB_P012878_ACT_plantpepdb_0004	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	PPepDB_8plantpepdb / linked
CTPDB_P012878_ACT_satpdb_0005	Metabolic/Cardiovascular	Antihypertensive	Not available for this observation	Unknown	Not reported by source	satpdb21474satpdb / linked

Provenance

Source database records (6)

ahtpdb

4260

Raw sequence

AKYSY

ahtpdb

2308

Raw sequence

AKYSY

ahtpdb

6676

Raw sequence

AKYSY

ahtpdb

5008

Raw sequence

AKYSY

plantpepdb

PPepDB_8

Raw sequence

AKYSY

satpdb

satpdb21474

Raw sequence

AKYSY

Citation trail

Literature (4 records)

Antihypertensive peptides from food proteins: a review.

Martínez-Maqueda D1, Miralles B, Recio I, Hernández-Ledesma B.

Food Funct. 2012 Apr;3(4):350-61.2012PMID 22249830

A new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides.

Sagardia I1, Roa-Ureta RH, Bald C.

Food Chem. 2013 Feb 15;136(3-4):1370-6.2013PMID 23194537

ACE inhibitory peptides

Yoshinori Mine, Fereidoon Shahidi

Nutraceutical Proteins and Peptides in Health and Disease (Nutraceutical Science and Technology)2005

Is the structural diversity of tripeptides sufficient for developing functional food additives with satisfactory multiple bioactivities?

Jian-Hui Wang et al.,

Journal of Molecular Structure 1040 (2013) 164-1702013

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:10.991164+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCCCC"
}