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PEPDIA-INT-004339

Gold

Pseudin-2

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

GLNALKKVFQGIHEAIKLINNHVQ

Indexed sequence24 aa

1GLNALKKVFQGIHEAIKLINNHVQ

Length

Molecular weight

2685.18 Da

Formula

C122H202N36O32

Structure type

Linear

Synthesis

Ribosomal

Chirality

Mixed

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic11

Membrane affinity proxy

Polar5

Solubility proxy

Charged6

Net charge proxy +4

Aromatic3

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

2685.1308 Da

Molecular formula

C122H202N36O32

Theoretical pI

9.7033

Net charge at pH 7

1.9343

GRAVY

-0.0083

Instability index

-2.9625

Aromaticity

0.0417

Topological polar surface area

1120.79 Å²

cLogP

-8.9768

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

GLNALKKVFQGIHEAIKLINNHVQ

HELM 2.0

validated simple linear

PEPTIDE1{G.L.N.A.L.K.K.V.F.Q.G.I.H.E.A.I.K.L.I.N.N.H.V.Q}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)CN)C(C)C)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(C(=O)NC(CCC(N)=O)C(=O)O)C(C)C)C(C)CC)C(C)CC

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)CN)C(C)C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)O)C(C)C)[C@@H](C)CC)[C@@H](C)CC

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-004339,
  title = {Pseudin-2},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-004339},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Pseudin-2. (2026). PepDiana record PEPDIA-INT-004339. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-004339

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (94 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P004339_ACT_apd_0000	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	AP00476apd / linked
CTPDB_P004339_ACT_apd_0001	Metabolic/Cardiovascular	Antidiabetic	Not available in the current structured import	Unknown	Not reported by source	AP00476apd / linked
CTPDB_P004339_ACT_apd_0002	Immunomodulatory	Anti-sepsis	Not available in the current structured import	Unknown	Not reported by source	AP00476apd / linked
CTPDB_P004339_ACT_camp_0003	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ243camp / linked
CTPDB_P004339_ACT_camp_0004	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ243camp / linked
CTPDB_P004339_ACT_camp_0005	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ243camp / linked
CTPDB_P004339_ACT_camp_0006	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	CAMPSQ9497camp / linked
CTPDB_P004339_ACT_dbaasp_0007	Antimicrobial	-	8 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0008	Antimicrobial	-	>64 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0009	Antimicrobial	-	32 µM	Staphylococcus aureus	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0010	Antimicrobial	-	4 µM	Listeria monocytogenes KCTC 3710	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0011	Antimicrobial	-	8 µM	Listeria monocytogenes KCTC 3710	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0012	Antimicrobial	-	32 µM	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0013	Antimicrobial	-	128 µM	Staphylococcus aureus ATCC 25923	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0014	Antimicrobial	-	2 µM	Bacillus subtilis KCTC 1998	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0015	Antimicrobial	-	4 µM	Bacillus subtilis KCTC 1998	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0016	Antimicrobial	-	2 µM	Bacillus megaterium KCTC 3709	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0017	Antimicrobial	-	4 µM	Bacillus megaterium KCTC 3709	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0018	Antimicrobial	-	32 µM	Staphylococcus epidermidis ATCC 12228	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0019	Antimicrobial	-	64 µM	Staphylococcus epidermidis ATCC 12228	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0020	Antimicrobial	-	2 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0021	Antimicrobial	-	4 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0022	Antimicrobial	-	8 µM	Pseudomonas aeruginosa ATCC 15692	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0023	Antimicrobial	-	16 µM	Pseudomonas aeruginosa ATCC 15692	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0024	Antimicrobial	-	2 µM	Salmonella typhimurium KCTC 1926	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0025	Antimicrobial	-	4 µM	Salmonella typhimurium KCTC 1926	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0026	Antimicrobial	-	2 µM	Enterobacter cloacae KCTC 2361	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0027	Antimicrobial	-	4 µM	Enterobacter cloacae KCTC 2361	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0028	Antimicrobial	-	2 µM	Klebsiella pneumoniae NCTC 8805	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0029	Antimicrobial	-	4 µM	Klebsiella pneumoniae NCTC 8805	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0030	Antimicrobial	-	16 µM	Staphylococcus aureus CCARM 3089	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0031	Antimicrobial	-	128 µM	Staphylococcus aureus CCARM 3089	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0032	Antimicrobial	-	16 µM	Staphylococcus aureus CCARM 3114	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0033	Antimicrobial	-	128 µM	Staphylococcus aureus CCARM 3114	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0034	Antimicrobial	-	4 µM	Salmonella typhimurium CCARM 8009	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0035	Antimicrobial	-	8 µM	Salmonella typhimurium CCARM 8009	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0036	Antimicrobial	-	2 µM	Salmonella typhimurium CCARM 8013	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0037	Antimicrobial	-	8 µM	Salmonella typhimurium CCARM 8013	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0038	Antimicrobial	-	1 µM	Escherichia coli CCARM 1229	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0039	Antimicrobial	-	4 µM	Escherichia coli CCARM 1229	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0040	Antimicrobial	-	1 µM	Escherichia coli CCARM 1238	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0041	Antimicrobial	-	4 µM	Escherichia coli CCARM 1238	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0042	Antimicrobial	-	4 µM	Pseudomonas aeruginosa 4007	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0043	Antimicrobial	-	8 µM	Pseudomonas aeruginosa 4007	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0044	Antimicrobial	-	4 µM	Pseudomonas aeruginosa 3547	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0045	Antimicrobial	-	8 µM	Pseudomonas aeruginosa 3547	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0046	Antimicrobial	-	8 µM	Candida albicans KCTC 7270	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0047	Antimicrobial	-	16 µM	Candida albicans KCTC 7270	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0048	Antimicrobial	-	8 µM	Trichosporon beigelii KCTC 7707	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0049	Antimicrobial	-	16 µM	Trichosporon beigelii KCTC 7707	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0050	Antimicrobial	-	16 µM	Aspergillus parasiticus KCTC 6598	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0051	Antimicrobial	-	32 µM	Aspergillus parasiticus KCTC 6598	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0052	Antimicrobial	-	32 µM	Aspergillus flavus KCTC 6905	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0053	Antimicrobial	-	64 µM	Aspergillus flavus KCTC 6905	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0054	Antimicrobial	-	8 µM	Penicillium verrucosum KCTC 6265	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0055	Antimicrobial	-	16 µM	Penicillium verrucosum KCTC 6265	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0056	Antimicrobial	-	64 µM	Aspergillus flavus KCTC 6905	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0057	Antimicrobial	-	16 µM	Aspergillus flavus KCTC 6905	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0058	Antimicrobial	-	64 µM	Aspergillus fumigatus KCTC 6145	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0059	Antimicrobial	-	24 µM	Aspergillus fumigatus KCTC 6145	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0060	Antimicrobial	-	32 µM	Fusarium verticillioides KCTC 6149	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0061	Antimicrobial	-	64 µM	Fusarium verticillioides KCTC 6149	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0062	Antimicrobial	-	4 µM	Fusarium oxysporum KCTC 16909	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0063	Antimicrobial	-	16 µM	Fusarium oxysporum KCTC 16909	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0064	Antimicrobial	-	12 µM	Candida albicans KCTC 7270	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0065	Antimicrobial	-	32 µM	Candida albicans KCTC 7270	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0066	Antimicrobial	-	8 µM	Candida krusei CCARM 14017	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0067	Antimicrobial	-	>64 µM	Candida parapsilosis CCARM 14016	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0068	Antimicrobial	-	4 µM	Candida tropicalis KCTC 7221	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0069	Antimicrobial	-	2 µM	Candida tropicalis KCTC 7221	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0070	Antimicrobial	-	2 µM	Trichosporon beigelii KCTC 7707	Not reported by source	DBAASPS_3355_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0071	Antimicrobial	-	2.5 µM	Escherichia coli	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0072	Antimicrobial	-	80 µM	Staphylococcus aureus	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0073	Antimicrobial	-	130 µM	Candida albicans	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0074	Antimicrobial	-	20 µM	Escherichia coli ATCC 25922	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0075	Antimicrobial	-	>80 µM	Staphylococcus aureus NCTC 8325	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0076	Antimicrobial	-	80 µM	Enterobacter cloacae HNTCC 53001	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0077	Antimicrobial	-	40 µM	Klebsiella pneumoniae KK3 9904	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0078	Antimicrobial	-	80 µM	Pseudomonas aeruginosa ATCC 27853	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0079	Antimicrobial	-	>80 µM	Proteus mirabilis ATCC 25933	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0080	Antimicrobial	-	80 µM	Staphylococcus epidermidis RP62A	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0081	Antimicrobial	-	80 µM	Streptococcus group B HNTCC 80130	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0082	Antimicrobial	-	>80 µM	Enterococcus faecalis ATCC 29212	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dbaasp_0083	Antimicrobial	-	>80 µM	Candida albicans ATCC 90028	Not reported by source	DBAASPS_3357_chain0dbaasp / linked
CTPDB_P004339_ACT_dramp_0084	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP02285dramp / linked
CTPDB_P004339_ACT_dramp_0085	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	DRAMP02285dramp / linked
CTPDB_P004339_ACT_dramp_0086	Antimicrobial	Anti-Gram+	Not available in the current structured import	Unknown	Not reported by source	DRAMP02285dramp / linked
CTPDB_P004339_ACT_dramp_0087	Antimicrobial	Anti-Gram-	Not available in the current structured import	Unknown	Not reported by source	DRAMP02285dramp / linked
CTPDB_P004339_ACT_dramp_0088	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	DRAMP02285dramp / linked
CTPDB_P004339_ACT_hemolytik_0089	Toxicity	Hemolytic	300.0 µM	Erythrocytes	Not reported by source	3527hemolytik / linked
CTPDB_P004339_ACT_satpdb_0090	Antimicrobial	Antibacterial	Not available in the current structured import	Unknown	Not reported by source	satpdb26169satpdb / linked
CTPDB_P004339_ACT_satpdb_0091	Toxicity	General Toxic	Not available in the current structured import	Unknown	Not reported by source	satpdb26169satpdb / linked
CTPDB_P004339_ACT_satpdb_0092	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	satpdb26169satpdb / linked
CTPDB_P004339_ACT_satpdb_0093	Antimicrobial	Antifungal	Not available in the current structured import	Unknown	Not reported by source	satpdb26169satpdb / linked

Provenance

Source database records (8)

apd

AP00476

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

camp

CAMPSQ243

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

camp

CAMPSQ9497

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

dbaasp

DBAASPS_3355_chain0

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

dbaasp

DBAASPS_3357_chain0

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

dramp

DRAMP02285

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

hemolytik

3527

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

satpdb

satpdb26169

Raw sequence

GLNALKKVFQGIHEAIKLINNHVQ

Citation trail

Literature (6 records)

Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

Olson L. III, Soto AM., Knoop FC., Conlon JM2001

--PMID 11689009

-

--PMID 31102497

Computational design of highly selective antimicrobial peptides.

Juretic D, Vukicevic D, Ilic N, Antcheva N, Tossi A

J Chem Inf Model2009PMID 19947578

Computational design of highly selective antimicrobial peptides.

Juretic D, Vukicevic D, Ilic N, Antcheva N, Tossi A

J Chem Inf Model2009PMID 20826126

Computational design of highly selective antimicrobial peptides.

Juretic D, Vukicevic D, Ilic N, Antcheva N, Tossi A

J Chem Inf Model2009PMID 33352972

Pseudin-2: an antimicrobial peptide with low hemolytic activity from the skin of the paradoxical frog.

Olson L 3rd, Soto AM, Knoop FC, Conlon JM

Biochem Biophys Res Commun2001PMID 15927702

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.941613+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET

{
  "toxicity": [
    {
      "unit": "µM",
      "value": "50",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "100",
      "source_db": "dbaasp",
      "assay_method": "39% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "64",
      "source_db": "dbaasp",
      "assay_method": "32% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human keratinocytes HaCat"
    },
    {
      "unit": "µM",
      "value": "128",
      "source_db": "dbaasp",
      "assay_method": "40%Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human keratinocytes HaCat"
    },
    {
      "unit": "µM",
      "value": "256",
      "source_db": "dbaasp",
      "assay_method": "79% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human keratinocytes HaCat"
    },
    {
      "unit": "µM",
      "value": "64",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Mouse erythrocytes"
    },
    {
      "unit": "µM",
      "value": "360",
      "source_db": "dbaasp",
      "assay_method": "50% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "source_db": "dramp",
      "assay_method": "[Ref.11689009]50% hemolysis of human erythrocytes is >300 μM",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Erythrocytes"
    }
  ]
}

Source metadata

[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCHHHHHHHTTTHHHHHTTTSCCC"
}