ProForma 2.0
validated simple linear
GCPWEPWC
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PEPDIA-INT-000721
SilverPepDiana tier derived from the internal quality score plus activity and literature coverage; it is not an external database rating.Contryphan-Tx/R
65
Quality PepDiana 0–100 composite of sequence, source, activity, literature, and cross-database evidence completeness.
2
Source DBs
1
Activities
4
Source refs
3
Literature
0
Patents
Integrated record
Sequence and molecular profile
GCPWEPWC
Indexed sequence8 aa
1GCPWEPWC
Length
8
Molecular weight
977.14 Da
Formula
C45H56N10O11S2
Structure type
Linear
Synthesis
-
Chirality
-
Family
-
Gene
-
Residue composition
C
2
P
2
W
2
G
1
E
1
Physicochemical profile
Hydrophobic2
Membrane affinity proxy
Polar2
Solubility proxy
Charged1
Net charge proxy -1
Aromatic2
Binding interaction proxy
Versioned scientific descriptors
Physicochemical properties and standard representations
Reported properties
Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.
Computed properties
physchem-20260620Molecular weight
977.1166 Da
Molecular formula
C45H56N10O11S2
Theoretical pI
4.05
Net charge at pH 7
-1.2569
GRAVY
-0.4875
Instability index
49.7
Aromaticity
0.25
Topological polar surface area
318.32 Ų
cLogP
-0.3919
Hydrogen-bond donors
12
Hydrogen-bond acceptors
12
Rotatable bonds
22
Method: PepDiana sequence/structure descriptor pipeline
Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6
Calculated: 2026-06-20T11:01:38.358971+00:00
Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200
Sequence representations
HELM 2.0
validated simple linear
PEPTIDE1{G.C.P.W.E.P.W.C}$$$$V2.0
Canonical SMILES
validated
NCC(=O)NC(CS)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CS)C(=O)O
Isomeric SMILES
validated
NCC(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O
Follow-up research
External analysis tools
Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.
Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.
Research workflow
Citation and local history
BibTeX
@misc{PEPDIA-INT-000721,
title = {Contryphan-Tx/R},
author = {{PepDiana Consortium}},
year = {2026},
howpublished = {PepDiana Multifunctional Peptide Database},
url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-000721},
note = {Accessed from local PepDiana development build}
}APA-style note
Contryphan-Tx/R. (2026). PepDiana record PEPDIA-INT-000721. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-000721
This record is saved to local recent-view history so it can reappear on the peptide browser page.
Integrated source-database annotations
Biological activity (1 records)
| Stable record | Activity | Subtype | Value | Target | Assay method | Source |
|---|---|---|---|---|---|---|
| CTPDB_P000721_ACT_satpdb_0000 | Toxicity | General Toxic | Not available in the current structured import | Unknown | Not reported by source | satpdb11004satpdb / linked |
Provenance
Source database records (4)
Citation trail
Literature (3 records)
Audit surface
Raw annotations and release metadata
Integrated record last updated: 2026-04-15T00:59:17.076483+00:00
Modification summary
No structured modification annotations are available for this record.
Source metadata
[
{
"source_db": "conoserver",
"organism_name": "Unknown"
},
{
"source_db": "satpdb",
"organism_name": "Unknown"
}
]Structure metadata
{
"source_db": "satpdb",
"dssp_states": "CCSSSSCC"
}