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PEPDIA-INT-059227

Gold

Temporin-A

85

Quality

8

Source DBs

109

Activities

24

Source refs

22

Literature

1

Patents

Integrated record

Sequence and molecular profile

FLPLIGRVLSGIL
Indexed sequence13 aa
1FLPLIGRVLSGIL

Length

13

Molecular weight

1397.77 Da

Formula

C68H116N16O15

Structure type

Linear

Synthesis

Ribosomal

Chirality

L

Family

-

Gene

-

Residue composition

L
4
I
2
G
2
F
1
P
1
R
1
V
1
S
1

Physicochemical profile

Hydrophobic8

Membrane affinity proxy

Polar1

Solubility proxy

Charged1

Net charge proxy +1

Aromatic1

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

1397.7465 Da

Molecular formula

C68H116N16O15

Theoretical pI

9.75

Net charge at pH 7

0.7601

GRAVY

1.8077

Instability index

32.3308

Aromaticity

0.0769

Topological polar surface area

485.86 Ų

cLogP

-0.5842

Hydrogen-bond donors

17

Hydrogen-bond acceptors

16

Rotatable bonds

44

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

FLPLIGRVLSGIL

HELM 2.0

validated simple linear

PEPTIDE1{F.L.P.L.I.G.R.V.L.S.G.I.L}$$$$V2.0

Canonical SMILES

validated

CCC(C)C(NC(=O)CNC(=O)C(CO)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(NC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)C(CC(C)C)NC(=O)C(N)Cc1ccccc1)C(C)CC)C(C)C)C(=O)NC(CC(C)C)C(=O)O

Isomeric SMILES

validated

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-059227,
  title = {Temporin-A},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-059227},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Temporin-A. (2026). PepDiana record PEPDIA-INT-059227. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-059227

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (109 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P059227_ACT_apd_0000AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0001Antiviral-Not available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0002AntimicrobialAntifungalNot available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0004Antiparasitic-Not available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0005BioregulatoryChemotacticNot available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0006Wound HealingWound HealingNot available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_apd_0007Anticancer-Not available in the current structured importUnknownNot reported by sourceAP00094apd / linked
CTPDB_P059227_ACT_camp_0008AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ30camp / linked
CTPDB_P059227_ACT_camp_0009AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceCAMPSQ30camp / linked
CTPDB_P059227_ACT_cancerppd_0012AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay1427cancerppd / linked
CTPDB_P059227_ACT_cancerppd_0013Antimicrobial-Not available in the current structured importUnknownMTT/MTS assay1427cancerppd / linked
CTPDB_P059227_ACT_cancerppd_0010AnticancerAnticancerNot available in the current structured importUnknownMTT/MTS assay4598cancerppd / linked
CTPDB_P059227_ACT_cancerppd_0011Antimicrobial-Not available in the current structured importUnknownMTT/MTS assay4598cancerppd / linked
CTPDB_P059227_ACT_dbaasp_0079Antimicrobial-193 µg/mlBatrachochytrium dendrobatidisNot reported by sourceDBAASPS_1128_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0080Antimicrobial->35 µg/mlBatrachochytrium dendrobatidisNot reported by sourceDBAASPS_1128_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0014Antimicrobial-1.2 µMBacillus megaterium Bm11Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0015Antimicrobial-2.3 µMStaphylococcus aureus Cowan 1Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0016Antimicrobial-2.0 µMYersinia pseudotuberculosisNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0017Antimicrobial-2.0 µMStreptococcus pyogenes Beta-hemolytic group ANot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0018Antimicrobial-11.9 µMEscherichia coli D21Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0019Antimicrobial-1.4 µMEscherichia coli D21e7Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0020Antimicrobial-0.9 µMEscherichia coli D21f1Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0021Antimicrobial-4.8 µMEscherichia coli D21f2Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0022Antimicrobial-3.4 µMEscherichia coli D22Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0023Antimicrobial->360 µMPseudomonas aeruginosa ATCC 15692Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0024Antimicrobial-3.4 µMCandida albicansNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0025Antimicrobial-5.2 µMStaphylococcus aureus K52Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0026Antimicrobial-2.6 µMStaphylococcus aureus K35Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0027Antimicrobial-2.6 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0028Antimicrobial-20.9 µMEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0029Antimicrobial-10.5 µMEnterococcus faeciumNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0030Antimicrobial-140 µg/mlBatrachochytrium dendrobatidisNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0031Antimicrobial-15 µMChannel Catfish VirusNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0032Antimicrobial-58 µMFrog Virus 3Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0033Antimicrobial-8.4 µMLeishmania donovani MHOM/S.D./00/1S-2D (amastigote)Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0034Antimicrobial-8.4 µMLeishmania donovani MHOM/S.D./00/1S-2D (promastigote)Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0035Antimicrobial-100 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0036Antimicrobial-20 µMYersinia pseudotuberculosis YPIIINot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0037Antimicrobial-5-6 µMStaphylococcus aureus Cowan 1Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0038Antimicrobial-2.5-3 µMBacillus megaterium Bm11Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0039Antimicrobial-5 µMStaphylococcus capitis 1Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0040Antimicrobial-5 µMCandida albicans ATCC 10231Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0041Antimicrobial->200 µMEscherichia coliNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0042Antimicrobial->200 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0043Antimicrobial->200 µMKlebsiella pneumoniae ATCC 13883Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0044Antimicrobial->200 µMSalmonella enterica subsp. enterica serovar Typhimurium ATCC 14028Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0045Antimicrobial-25 µMBacillus subtilisNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0046Antimicrobial-25 µMStreptococcus pyogenes ATCC 19615Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0047Antimicrobial-25 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0048Antimicrobial-50 µMEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0049Antimicrobial-128 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0050Antimicrobial-128 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0051Antimicrobial-8 µg/mlStaphylococcus aureus NBRC 100910Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0052Antimicrobial-8 µMCorynebacterium jeikeium ATCC BAA-949Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0053Antimicrobial-8 µg/mlStaphylococcus aureus 357426Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0054Antimicrobial-4 µg/mlStaphylococcus aureus 355872Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0055Antimicrobial-4 µg/mlStaphylococcus aureus 348839Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0056Antimicrobial-4-8 µg/mlStaphylococcus aureus MRNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0057Antimicrobial-8 µg/mlStaphylococcus aureus ATCC 43300Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0058Antimicrobial-8 µg/mlStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0059Antimicrobial-512 µg/mlPseudomonas aeruginosa ATCC 9029Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0060Antimicrobial-100 µMEscherichia coli D21Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0061Antimicrobial-200 µMPseudomonas aeruginosa ATCC 15692Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0062Antimicrobial-400 µMAeromonas hydrophila Rt-6Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0063Antimicrobial-3 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0064Antimicrobial-3 µMStaphylococcus epidermidis ATCC 12228Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0065Antimicrobial-10 µg/mlStaphylococcus aureus A170Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0066Antimicrobial-20 µg/mlStaphylococcus aureus A172Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0067Antimicrobial-10 µg/mlStaphylococcus aureus 007Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0068Antimicrobial-30 µg/mlListeria monocytogenesNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0069Antimicrobial-400 µg/mlSalmonella enterica subsp. enterica serovar Paratyphi ANot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0070Antimicrobial-125 µg/mlEscherichia coliNot reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0071AnticancerCytotoxic31 µMHuman lung carcinoma A549Not reported by sourceDBAASPS_506_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0072Antimicrobial-3.1 µMStaphylococcus aureus K52Not reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0073Antimicrobial-3.1 µMStaphylococcus aureus K35Not reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0074Antimicrobial-2.6 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0075Antimicrobial-10.5 µMEnterococcus faecalis ATCC 29212Not reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0076Antimicrobial-12.5 µMEnterococcus faeciumNot reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0077Antimicrobial-8.7 µg/mlBatrachochytrium dendrobatidisNot reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0078Antimicrobial-8 µg/mlStaphylococcus aureus NBRC 100910Not reported by sourceDBAASPS_720_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0081Antimicrobial->100 µMBacillus subtilis ATCC 9372Not reported by sourceDBAASPS_7382_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0082Antimicrobial->100 µMBacillus anthracis Sterne 34F2Not reported by sourceDBAASPS_7382_chain0dbaasp / linked
CTPDB_P059227_ACT_dbaasp_0083Antimicrobial->50 µMBurkholderia thailandensisNot reported by sourceDBAASPS_7382_chain0dbaasp / linked
CTPDB_P059227_ACT_dramp_0084Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP01730dramp / linked
CTPDB_P059227_ACT_dramp_0085AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP01730dramp / linked
CTPDB_P059227_ACT_dramp_0086AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceDRAMP01730dramp / linked
CTPDB_P059227_ACT_dramp_0087AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceDRAMP01730dramp / linked
CTPDB_P059227_ACT_dramp_0088Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP27794dramp / linked
CTPDB_P059227_ACT_dramp_0089AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceDRAMP27794dramp / linked
CTPDB_P059227_ACT_hemolytik_0091ToxicityHemolytic14.0 µMErythrocytesNot reported by source2151hemolytik / linked
CTPDB_P059227_ACT_hemolytik_0092ToxicityHemolytic225.0 µMErythrocytesNot reported by source2152hemolytik / linked
CTPDB_P059227_ACT_hemolytik_0093ToxicityHemolytic40.0 µMErythrocytesNot reported by source2879hemolytik / linked
CTPDB_P059227_ACT_hemolytik_0094ToxicityHemolytic1.25 µMErythrocytesNot reported by source2880hemolytik / linked
CTPDB_P059227_ACT_hemolytik_0095ToxicityHemolytic120.0 µMErythrocytesNot reported by source3373hemolytik / linked
CTPDB_P059227_ACT_hemolytik_0090ToxicityHemolytic120.0 µMErythrocytesNot reported by source4110hemolytik / linked
CTPDB_P059227_ACT_parapep_0096AntiparasiticAntiparasiticNot available in the current structured importUnknownMTT assay1240parapep / linked
CTPDB_P059227_ACT_parapep_0097AntiparasiticAntiparasiticNot available in the current structured importUnknownMTT assay1241parapep / linked
CTPDB_P059227_ACT_parapep_0098AntiparasiticAntiparasitic8.4 µMUnknownMTT assay1242parapep / linked
CTPDB_P059227_ACT_parapep_0099AntiparasiticAntiparasitic12.0 µMUnknownMTT assay1349parapep / linked
CTPDB_P059227_ACT_parapep_0100AntiparasiticAntiparasiticNot available in the current structured importUnknownAlamar Blue assay1605parapep / linked
CTPDB_P059227_ACT_parapep_0101AntiparasiticAntiparasiticNot available in the current structured importUnknownAlamar Blue assay1607parapep / linked
CTPDB_P059227_ACT_satpdb_0102Anticancer-Not available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0103AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0104Antiviral-Not available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0105Antiparasitic-Not available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0106ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0107Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0108AntimicrobialAntifungalNot available in the current structured importUnknownNot reported by sourcesatpdb12693satpdb / linked
CTPDB_P059227_ACT_satpdb_0109Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb26691satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

7

Records

1

Papers

5

Positive

2

Negative

1

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-003521View all experimental records

Provenance

Source database records (24)

Source-specific sequence or modification context. One or more source records use a sequence notation that differs from the canonical backbone. Open each raw sequence before interpreting stereochemistry, terminal groups, or non-standard residues.

apd

AP00094

Raw sequence

FLPLIGRVLSGIL

camp

CAMPSQ30

Raw sequence

FLPLIGRVLSGIL

cancerppd

4598

Raw sequence

FLPLIGRVLSGIL

cancerppd

1427

Raw sequence

FLPLIGRVLSGIL

dbaasp

DBAASPS_506_chain0

Raw sequence

FLPLIGRVLSGIL

dbaasp

DBAASPS_720_chain0

Raw sequence

flpliGrvlsGil

dbaasp

DBAASPS_1128_chain0

Raw sequence

FlPlIGRvLsGiL

dbaasp

DBAASPS_7382_chain0

Raw sequence

FLPLIGRVLSGIL

dramp

DRAMP01730

Raw sequence

FLPLIGRVLSGIL

dramp

DRAMP27794

Raw sequence

FLPLIGRVLSGIL

hemolytik

4110

Raw sequence

FLPLIGRVLSGIL

hemolytik

2151

Raw sequence

FLPLIGRVLSGIL

hemolytik

2152

Raw sequence

FLPLIGRVLSGIL

hemolytik

2879

Raw sequence

FLPLIGRVLSGIL

hemolytik

2880

Raw sequence

FLPLIGRVLSGIL

hemolytik

3373

Raw sequence

FLPLIGRVLSGIL

parapep

1240

Raw sequence

FLPLIGRVLSGIL

parapep

1241

Raw sequence

FLPLIGRVLSGIL

parapep

1242

Raw sequence

FLPLIGRVLSGIL

parapep

1349

Raw sequence

FLPLIGRVLSGIL

parapep

1605

Raw sequence

FLPLIGRVLSGIL

parapep

1607

Raw sequence

FLPLIGRVLSGIL

satpdb

satpdb12693

Raw sequence

FLPLIGRVLSGIL

satpdb

satpdb26691

Raw sequence

FLPLIGRVLSGIL

Citation trail

Literature (22 records)

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D.1996

Eur J Biochem1996PMID 9022710

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 10940378

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 12604562

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 15193922

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 15513914

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 21337476

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 24419338

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 28262682

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 32722535

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 30345920

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 31678322

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 32887236

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 16867990

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 19784377

Temporins, antimicrobial peptides from the European red frog Rana temporaria.

Simmaco M, Mignogna G, Canofeni S, Miele R, Mangoni ML, Barra D

Eur J Biochem1996PMID 33538061

Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis.

Liu CQ, McAllister J, Dawson RM

Int J Antimicrob Agents2010PMID 20692130

IP evidence

Patents (1)

US 10723764

dramp

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.941613+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "unit": "µM",
      "value": "40",
      "source_db": "dbaasp",
      "assay_method": "28% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "20",
      "source_db": "dbaasp",
      "assay_method": "13% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "10",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "5",
      "source_db": "dbaasp",
      "assay_method": "4% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": "2.5",
      "source_db": "dbaasp",
      "assay_method": "1% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "7.91",
      "source_db": "dbaasp",
      "assay_method": "IC50",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human keratinocytes HaCat"
    },
    {
      "unit": "µM",
      "value": ">100",
      "source_db": "dbaasp",
      "assay_method": "1% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "source_db": "dramp",
      "assay_method": "[Ref.9022710] LC>120 µM against Human red blood cells. (LC: Lethal concentration)",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Erythrocytes"
    }
  ]
}
Source metadata
[
  {
    "source_db": "apd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "cancerppd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "parapep",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "pdb_id": "2MAA resolved by NMR.",
  "source_db": "dramp"
}