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PEPDIA-INT-025613

Silver

Tyroserleutide

Quality

Source DBs

Activities

Source refs

Literature

Patents

Integrated record

Sequence and molecular profile

YSL

Indexed sequence3 aa

1YSL

Length

Molecular weight

381.43 Da

Formula

C18H27N3O6

Structure type

Linear

Synthesis

Chirality

Family

Gene

Residue composition

Physicochemical profile

Hydrophobic2

Membrane affinity proxy

Polar1

Solubility proxy

Charged0

Net charge proxy +0

Aromatic1

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

381.4234 Da

Molecular formula

C18H27N3O6

Theoretical pI

5.5243

Net charge at pH 7

-0.2409

GRAVY

0.5667

Instability index

6.6667

Aromaticity

0.3333

Topological polar surface area

161.98 Å²

cLogP

-0.6454

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

YSL

HELM 2.0

validated simple linear

PEPTIDE1{Y.S.L}$$$$V2.0

Canonical SMILES

validated

CC(C)CC(NC(=O)C(CO)NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

Isomeric SMILES

validated

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-025613,
  title = {Tyroserleutide},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-025613},
  note = {Accessed from local PepDiana development build}
}

APA-style note

Tyroserleutide. (2026). PepDiana record PEPDIA-INT-025613. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-025613

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (12 records)

Stable record	Activity	Subtype	Value	Target	Assay method	Source
CTPDB_P025613_ACT_cancerppd_0000	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4219cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0001	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4220cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0002	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4221cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0003	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4222cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0004	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4223cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0005	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4224cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0006	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4225cancerppd / linked
CTPDB_P025613_ACT_cancerppd_0007	Anticancer	Anticancer	Not available in the current structured import	Unknown	MTT/MTS assay	4226cancerppd / linked
CTPDB_P025613_ACT_dramp_0008	Antimicrobial	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP31630dramp / linked
CTPDB_P025613_ACT_dramp_0009	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	DRAMP31630dramp / linked
CTPDB_P025613_ACT_plantpepdb_0010	Antioxidant	-	Not available in the current structured import	Unknown	Not reported by source	PPepDB_3714plantpepdb / linked
CTPDB_P025613_ACT_satpdb_0011	Anticancer	-	Not available in the current structured import	Unknown	Not reported by source	satpdb12841satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

Records

Papers

Positive

Negative

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-004213 View all experimental records

Provenance

Source database records (11)

cancerppd

4219

Raw sequence

YSL

cancerppd

4220

Raw sequence

YSL

cancerppd

4221

Raw sequence

YSL

cancerppd

4222

Raw sequence

YSL

cancerppd

4223

Raw sequence

YSL

cancerppd

4224

Raw sequence

YSL

cancerppd

4225

Raw sequence

YSL

cancerppd

4226

Raw sequence

YSL

dramp

DRAMP31630

Raw sequence

YSL

plantpepdb

PPepDB_3714

Raw sequence

YSL

satpdb

satpdb12841

Raw sequence

YSL

Citation trail

Literature (1 records)

-

--PMID 16091933

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:16.851167+00:00

Modification summary

No structured modification annotations are available for this record.

Source metadata

[
  {
    "source_db": "cancerppd",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "plantpepdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]

Structure metadata

{
  "source_db": "satpdb",
  "dssp_states": "CCC"
}