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PEPDIA-INT-005869

Gold

MP-8

80

Quality

6

Source DBs

104

Activities

19

Source refs

8

Literature

0

Patents

Integrated record

Sequence and molecular profile

WW
Indexed sequence2 aa
1WW

Length

2

Molecular weight

390.44 Da

Formula

C22H22N4O3

Structure type

Linear

Synthesis

Synthetic

Chirality

L

Family

-

Gene

-

Residue composition

W
2

Physicochemical profile

Hydrophobic2

Membrane affinity proxy

Polar0

Solubility proxy

Charged0

Net charge proxy +0

Aromatic2

Binding interaction proxy

Versioned scientific descriptors

Physicochemical properties and standard representations

calculated sequence and structure

Reported properties

Legacy compatibility fields are materialized from the versioned PepDiana computed release; no separate source-reported property is available.

Computed properties

physchem-20260620

Molecular weight

390.4351 Da

Molecular formula

C22H22N4O3

Theoretical pI

5.525

Net charge at pH 7

-0.2399

GRAVY

-0.9

Instability index

5

Aromaticity

1

Topological polar surface area

124 Ų

cLogP

2.3311

Hydrogen-bond donors

5

Hydrogen-bond acceptors

3

Rotatable bonds

7

Method: PepDiana sequence/structure descriptor pipeline

Tool: Biopython+RDKit · Biopython 1.85; RDKit 2024.09.6

Calculated: 2026-06-20T11:01:38.358971+00:00

Assumptions: ph=7; termini=free N-terminus and free C-terminus for simple linear peptides; stereochemistry=standard L-amino acids; smiles_length_limit=200

Sequence representations

representations-20260620 · RDKit 2024.09.6

ProForma 2.0

validated simple linear

WW

HELM 2.0

validated simple linear

PEPTIDE1{W.W}$$$$V2.0

Canonical SMILES

validated

NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O

Isomeric SMILES

validated

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

Follow-up research

External analysis tools

Run BLASTPSearch similar protein or peptide sequences at NCBI.Search UniProtLook for related UniProtKB entries using the sequence.Search PubMedFind literature context for this peptide record.Search PubChemOpen chemistry search with the canonical SMILES string.

Links open third-party resources with the current PepDiana sequence, record name, or chemistry notation as the initial query.

Research workflow

Citation and local history

BibTeX

@misc{PEPDIA-INT-005869,
  title = {MP-8},
  author = {{PepDiana Consortium}},
  year = {2026},
  howpublished = {PepDiana Multifunctional Peptide Database},
  url = {http://127.0.0.1:3004/peptides/PEPDIA-INT-005869},
  note = {Accessed from local PepDiana development build}
}

APA-style note

MP-8. (2026). PepDiana record PEPDIA-INT-005869. PepDiana Multifunctional Peptide Database. http://127.0.0.1:3004/peptides/PEPDIA-INT-005869

This record is saved to local recent-view history so it can reappear on the peptide browser page.

Integrated source-database annotations

Biological activity (104 records)

Stable recordActivitySubtypeValueTargetAssay methodSource
CTPDB_P005869_ACT_ahtpdb_0000Metabolic/CardiovascularACE InhibitorNot available in the current structured importUnknownNot reported by source3882ahtpdb / linked
CTPDB_P005869_ACT_camp_0001AntimicrobialAntibacterialNot available in the current structured importUnknownNot reported by sourceCAMPSQ13204camp / linked
CTPDB_P005869_ACT_camp_0002AntimicrobialAnti-Gram+Not available in the current structured importUnknownNot reported by sourceCAMPSQ13204camp / linked
CTPDB_P005869_ACT_camp_0003AntimicrobialAnti-Gram-Not available in the current structured importUnknownNot reported by sourceCAMPSQ13204camp / linked
CTPDB_P005869_ACT_dbaasp_0046Antimicrobial->100 µMHuman myelogenous leukemia K562Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0047Antimicrobial->100 µMHuman ovarian adenocarcinoma A2780Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0048Antimicrobial->100 µMHuman ovarian adenocarcinoma A2780CisRNot reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0049Antimicrobial-12.5-25 µg/mlAcinetobacter baumanniiNot reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0050Antimicrobial->100 µg/mlAcinetobacter baumanniiNot reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0051Antimicrobial-50 µg/mlCandida albicans IFO 6258Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0052Antimicrobial-12.5 µg/mlMicrococcus luteus JCM 1464Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0053Antimicrobial-50 µg/mlBacillus subtilis IAM 1069Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0054Antimicrobial-25 µg/mlAspergillus niger ATCC 9642Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0055Antimicrobial->100 µg/mlStreptomyces murinus JCM 4333Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0056Antimicrobial-0.8 µg/mlStaphylococcus aureus TK784Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0057Antimicrobial-25 µg/mlSaccharomyces cerevisiae IFO 1008Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0058Antimicrobial->200 µMHuman cervical carcinoma HeLaNot reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0059Antimicrobial->200 µMHuman hepatocellular carcinoma HepG2Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0060Antimicrobial->200 µMHuman breast adenocarcinoma MCF-7Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0061Antimicrobial-32 µg/mlBacillus subtilis ATCC 23857Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0062Antimicrobial-16 µg/mlStaphylococcus aureus ATCC 12600Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0063Antimicrobial-NAStaphylococcus epidermidis ATCC 51625Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0064Antimicrobial-128 µg/mlStaphylococcus simulans ATCC 27848Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0065Antimicrobial-256 µg/mlEscherichia coli ATCC 35218Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0066Antimicrobial-NAKlebsiella pneumoniae ATCC 43816Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0067Antimicrobial-NAProteus mirabilis ATCC 21100Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0068Antimicrobial-256 µg/mlPseudomonas aeruginosa ATCC 10145Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0069Antimicrobial-64 µg/mlAspergillus flavus ATCC 204304Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0070Antimicrobial-128 µg/mlCandida albicans ATCC 10231Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0071Antimicrobial-64 µg/mlGoffeauzyma gastrica ATCC 32042Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0072Antimicrobial-64 µg/mlTrichophyton rubrum ATCC 28191Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0073Antimicrobial-64 µg/mlFusarium oxysporum ATCC 14838Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0074Antimicrobial-16 µg/mlRhizoctonia solani ATCC 10182Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0075Antimicrobial-16 µg/mlPenicillium expansum ATCC 16104Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0076Antimicrobial-NAAlternaria brassicae ATCC 66981Not reported by sourceDBAASPS_18861_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0077Antimicrobial-8 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0078Antimicrobial-8 µMBacillus subtilis ATCC 23857Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0079Antimicrobial-64 µMAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0080Antimicrobial-128 µMKlebsiella pneumoniae ATCC 700603Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0081Antimicrobial-8 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0082Antimicrobial-32 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0083Antimicrobial-16 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0084Antimicrobial->128 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0085Antimicrobial-64 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_22536_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0086Antimicrobial-16 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0087Antimicrobial-16 µMBacillus subtilis ATCC 23857Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0088Antimicrobial-128 µMAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0089Antimicrobial->128 µMKlebsiella pneumoniae ATCC 700603Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0090Antimicrobial->128 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0091Antimicrobial->128 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_22537_chain1dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0092Antimicrobial-8 µMStaphylococcus aureus ATCC 25923Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0093Antimicrobial-8 µMBacillus subtilis ATCC 23857Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0094Antimicrobial-32 µMAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0095Antimicrobial-64 µMKlebsiella pneumoniae ATCC 700603Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0096Antimicrobial-8 µMEscherichia coli ATCC 25922Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0097Antimicrobial-32 µMPseudomonas aeruginosa ATCC 27853Not reported by sourceDBAASPS_22540_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0004Antimicrobial-<512 µg/mlPseudomonas aeruginosa MTCCB 741Not reported by sourceDBAASPS_5096_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0005Antimicrobial-<512 µg/mlEscherichia coli MTCCB 1610Not reported by sourceDBAASPS_5096_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0006Antimicrobial-2 µg/mlStaphylococcus aureus MTCCB 96Not reported by sourceDBAASPS_5096_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0007Antimicrobial-1 µg/mlBacillus subtilis NCIM 2063Not reported by sourceDBAASPS_5096_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0008Antimicrobial-<512 µg/mlEscherichia coliNot reported by sourceDBAASPS_5096_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0009Antimicrobial->227.2 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7590_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0010Antimicrobial-113.6 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7590_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0011Antimicrobial->227.2 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0012Antimicrobial->227.2 µg/mlBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0013Antimicrobial->227.2 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0014Antimicrobial->227.2 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0015Antimicrobial->227.2 µg/mlEnterococcus faecalis ATCC 7080Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0016Antimicrobial->227.2 µg/mlStaphylococcus aureus ATCC 33591Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0017Antimicrobial->227.2 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_7593_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0018Antimicrobial->227.2 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0019Antimicrobial->227.2 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0020Antimicrobial->227.2 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0021Antimicrobial-113.6 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0022Antimicrobial->227.2 µg/mlEnterococcus faecalis ATCC 7080Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0023Antimicrobial-113.6 µg/mlBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0024Antimicrobial->227.2 µg/mlStaphylococcus aureus ATCC 33591Not reported by sourceDBAASPS_7614_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0025Antimicrobial->227.2 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7617_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0026Antimicrobial->227.2 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_7617_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0027Antimicrobial-227.2 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7617_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0028Antimicrobial-56.8 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7620_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0029Antimicrobial-113.6 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_7620_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0030Antimicrobial-56.8 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7620_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0031Antimicrobial-56.8 µg/mlBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_7620_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0032Antimicrobial-56.8 µg/mlStaphylococcus aureus ATCC 33591Not reported by sourceDBAASPS_7620_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0033Antimicrobial-22.7 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0034Antimicrobial-7.1 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0035Antimicrobial-28.4 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0036Antimicrobial-7.1 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0037Antimicrobial-14.2 µg/mlEnterococcus faecalis ATCC 7080Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0038Antimicrobial-3.5 µg/mlBacillus subtilis ATCC 6633Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0039Antimicrobial-0.8 µg/mlStaphylococcus aureus ATCC 33591Not reported by sourceDBAASPS_7622_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0040Antimicrobial->227.2 µg/mlEscherichia coli ATCC 11775Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0041Antimicrobial-113.6 µg/mlPseudomonas aeruginosa ATCC 25668Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0042Antimicrobial-56.8 µg/mlAcinetobacter baumannii ATCC 19606Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0043Antimicrobial-7.1 µg/mlStaphylococcus aureus ATCC 29213Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0044Antimicrobial->56.8 µg/mlEnterococcus faecalis ATCC 7080Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dbaasp_0045Antimicrobial-28.4 µg/mlStaphylococcus aureus ATCC 33591Not reported by sourceDBAASPS_7625_chain0dbaasp / linked
CTPDB_P005869_ACT_dramp_0098Antimicrobial-Not available in the current structured importUnknownNot reported by sourceDRAMP35734dramp / linked
CTPDB_P005869_ACT_dramp_0099Anticancer-Not available in the current structured importUnknownNot reported by sourceDRAMP35734dramp / linked
CTPDB_P005869_ACT_hemolytik_0100ToxicityHemolytic1000.0 µg/mlErythrocytesNot reported by source1924hemolytik / linked
CTPDB_P005869_ACT_satpdb_0101Metabolic/CardiovascularAntihypertensiveNot available in the current structured importUnknownNot reported by sourcesatpdb22770satpdb / linked
CTPDB_P005869_ACT_satpdb_0102ToxicityGeneral ToxicNot available in the current structured importUnknownNot reported by sourcesatpdb25897satpdb / linked
CTPDB_P005869_ACT_satpdb_0103Antimicrobial-Not available in the current structured importUnknownNot reported by sourcesatpdb25897satpdb / linked

Sequence-linked cross-layer evidence

Linked primary-literature evidence

2

Records

1

Papers

2

Positive

0

Negative

1

Primary identities

These observations were collected directly from primary literature and linked by identical normalized sequence. They remain a separate evidence layer and do not overwrite Integrated source-database annotations.

View PEPDIA-PLP-004173View all experimental records

Provenance

Source database records (19)

ahtpdb

3882

Raw sequence

WW

camp

CAMPSQ13204

Raw sequence

WW

dbaasp

DBAASPS_5096_chain0

Raw sequence

WW

dbaasp

DBAASPS_7590_chain0

Raw sequence

WW

dbaasp

DBAASPS_7593_chain0

Raw sequence

WW

dbaasp

DBAASPS_7614_chain0

Raw sequence

WW

dbaasp

DBAASPS_7617_chain0

Raw sequence

WW

dbaasp

DBAASPS_7620_chain0

Raw sequence

WW

dbaasp

DBAASPS_7622_chain0

Raw sequence

WW

dbaasp

DBAASPS_7625_chain0

Raw sequence

WW

dbaasp

DBAASPS_18861_chain0

Raw sequence

WW

dbaasp

DBAASPS_22536_chain1

Raw sequence

WW

dbaasp

DBAASPS_22537_chain1

Raw sequence

WW

dbaasp

DBAASPS_22538_chain0

Raw sequence

WW

dbaasp

DBAASPS_22540_chain0

Raw sequence

WW

dramp

DRAMP35734

Raw sequence

WW

hemolytik

1924

Raw sequence

WW

satpdb

satpdb22770

Raw sequence

WW

satpdb

satpdb25897

Raw sequence

WW

Citation trail

Literature (8 records)

Three-dimensional holograph vector of atomic interaction field (3D-HoVAIF): a novel rotation-translation invariant 3D structure descriptor and its applications to peptides.

Tian F1, Zhou P, Lv F, Song R, Li Z.

J Pept Sci. 2007 Aug;13(8):549-66.2007PMID 17654623

Antimicrobial activity of rationally designed amino terminal modified peptides.

Bisht GS, Rawat DS, Kumar A, Kumar R, Pasha S

Bioorg Med Chem Lett2007PMID 17553680

Synthesis, antibacterial activity and mode of action of novel linoleic acid-dipeptide-spermidine conjugates.

Joshi S, Dewangan RP, Yadav S, Rawat DS, Pasha S

Org Biomol Chem2012PMID 22986997

Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.

Wollinsky B, Ludwig L, Hamacher A, Yu X, Kassack MU, Li SM

Bioorg Med Chem Lett2012PMID 22617493

Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.

Wollinsky B, Ludwig L, Hamacher A, Yu X, Kassack MU, Li SM

Bioorg Med Chem Lett2012PMID 21193822

Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides.

Wollinsky B, Ludwig L, Hamacher A, Yu X, Kassack MU, Li SM

Bioorg Med Chem Lett2012PMID 32806659

Arginine and tryptophan-rich dendritic antimicrobial peptides that disrupt membranes for bacterial infection in vivo

Yang Y, Yu Z, Ba Z, Ouyang X, Yang P, Zhang J, Wang Y, Liu Y, Yang T, Zhao Y, Wu X, Zhong C, Liu H, Zhang Y, Gou S, Ni J

Eur J Med Chem2024PMID 38691892

Audit surface

Raw annotations and release metadata

Integrated record last updated: 2026-04-15T00:59:11.254051+00:00

Modification summary

No structured modification annotations are available for this record.

ADMET
{
  "toxicity": [
    {
      "source_db": "dbaasp",
      "assay_method": "-",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "16% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µg/ml",
      "value": "62.5",
      "source_db": "dbaasp",
      "assay_method": "0% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Human erythrocytes"
    },
    {
      "unit": "µM",
      "value": ">256",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Mouse erythrocytes"
    },
    {
      "unit": "µM",
      "value": ">128",
      "source_db": "dbaasp",
      "assay_method": "50% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human embryonic kidney HEK293T cells"
    },
    {
      "unit": "µM",
      "value": ">256",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Mouse erythrocytes"
    },
    {
      "unit": "µM",
      "value": ">128",
      "source_db": "dbaasp",
      "assay_method": "50% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human embryonic kidney HEK293T cells"
    },
    {
      "unit": "µM",
      "value": ">256",
      "source_db": "dbaasp",
      "assay_method": "10% Hemolysis",
      "toxicity_type": "Hemolytic",
      "target_cellline": "Mouse erythrocytes"
    },
    {
      "unit": "µM",
      "value": ">128",
      "source_db": "dbaasp",
      "assay_method": "50% Cell death",
      "toxicity_type": "Cytotoxic",
      "target_cellline": "Human embryonic kidney HEK293T cells"
    }
  ]
}
Source metadata
[
  {
    "source_db": "ahtpdb",
    "organism_name": "Unknown"
  },
  {
    "source_db": "camp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dbaasp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "dramp",
    "organism_name": "Unknown"
  },
  {
    "source_db": "hemolytik",
    "organism_name": "Unknown"
  },
  {
    "source_db": "satpdb",
    "organism_name": "Unknown"
  }
]
Structure metadata
{
  "source_db": "satpdb",
  "dssp_states": "CC"
}