PepDiana
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Primary experimental recordPositive observation

PMC13231543::ACT047738

sP10

Evidence text

Paper-level observation

Flow cytometry analysis revealed that sP10 increased the proportion of CD80-positive and CD86-positive M1 macrophages derived from BMDM cells (Fig. 6D).
figureConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Not reported by source
Measure
qualitative
Comparator
=
Raw observation
increased the proportion of CD80-positive and CD86-positive M1 macrophages
Normalized measurement
=0
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
BMDM
Assay method
Not reported by source
Sequence
YGRKKRRQRRRCGPVWFLIFSYFLFFSISLARGPC
Standardization
ready simple

Source publication

Peptide aptamer sP10 targeting NPM1 attenuates liver fibrosis and hepatocellular carcinoma.

Journal of Translational Medicine · 2026

DOI 10.1186/s12967-026-08144-8 PMC13231543
Parent mention

Related peptide identities

PEPDIA-PLP-003251

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.