Primary experimental recordPositive observation

PMC13231543::ACT047736

sP10

Evidence text

Paper-level observation

Confocal microscopy showed increased autophagosomes (yellow puncta) and autolysosomes (red puncta) after 24 h (Fig. 5E and F), confirming enhanced autophagic flux.

figureConfidence: medium

Assay observation

Activity

Anticancer

Subtype

Not reported by source

Measure

qualitative

Comparator

Raw observation

upregulated the autophagy flux

Normalized measurement

=24

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Hepa1-6

Assay method

Not reported by source

Sequence

YGRKKRRQRRRCGPVWFLIFSYFLFFSISLARGPC

Standardization

ready simple

Source publication

Peptide aptamer sP10 targeting NPM1 attenuates liver fibrosis and hepatocellular carcinoma.

Journal of Translational Medicine · 2026

DOI 10.1186/s12967-026-08144-8 PMC13231543

Parent mention

Related peptide identities

PEPDIA-PLP-003251

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.