PepDiana
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Primary experimental recordPositive observation

PMC13231543::ACT047732

sP10

Evidence text

Paper-level observation

The results of Sirius red staining, IHC analysis of liver tissues (as shown in Fig. 2E), and Western blotting (Fig. 2F) indicated that both sP10 and sP177 effectively decreased collagen synthesis and α-SMA expression in fibrotic liver tissue.
figureConfidence: medium

Assay observation

Activity
Metabolic/Cardiovascular
Subtype
Not reported by source
Measure
qualitative
Comparator
=
Raw observation
effectively decreased collagen synthesis and α-SMA expression
Normalized measurement
=0
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Not reported by source
Assay method
Not reported by source
Sequence
YGRKKRRQRRRCGPVWFLIFSYFLFFSISLARGPC
Standardization
ready simple

Source publication

Peptide aptamer sP10 targeting NPM1 attenuates liver fibrosis and hepatocellular carcinoma.

Journal of Translational Medicine · 2026

DOI 10.1186/s12967-026-08144-8 PMC13231543
Parent mention

Related peptide identities

PEPDIA-PLP-003251

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.