PepDiana
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Primary experimental recordPositive observation

PMC13231543::ACT047721

sP10

Evidence text

Paper-level observation

The proliferation curve demonstrated that both intracellular expression of peptide aptamers (P10 and P177) and incubation of synthetic peptides (sP10 and sP177) significantly decreased cell proliferation (Fig. 2A).
figureConfidence: medium

Assay observation

Activity
Anticancer
Subtype
Cytotoxic
Measure
cell_viability
Comparator
=
Raw observation
inhibited proliferation
Normalized measurement
=0
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
LX-2
Assay method
Not reported by source
Sequence
YGRKKRRQRRRCGPVWFLIFSYFLFFSISLARGPC
Standardization
ready simple

Source publication

Peptide aptamer sP10 targeting NPM1 attenuates liver fibrosis and hepatocellular carcinoma.

Journal of Translational Medicine · 2026

DOI 10.1186/s12967-026-08144-8 PMC13231543
Parent mention

Related peptide identities

PEPDIA-PLP-003251

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.