PepDiana
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Primary experimental recordPositive observation

PMC13117951::ACT043821

GRVPR

Evidence text

Paper-level observation

tuna peptide S6 demonstrated the strongest anti-inflammatory effect... At a concentration of 200 μM, the tuna peptide treatment groups (S1, S6, and S7) showed a significant reduction in these inflammatory markers compared to the model group. (Figure 4)
textConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
other
Comparator
=
Raw observation
strongest anti-inflammatory effect; significantly reduced IL-1β, IL-6, TNF-α
Normalized measurement
=1
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Mus musculus
Assay method
Not reported by source
Sequence
GRVPR
Standardization
ready simple

Source publication

Antioxidant Peptides from Skipjack tuna: Ameliorate Function on Cigarette Smoke Extract-Induced COPD in Cell Model by Targeting Oxidative Stress, Inflammation and Apoptosis

Marine Drugs · 2026

DOI 10.3390/md24040140 PMC13117951
Parent mention

Related peptide identities

PEPDIA-PLP-001112

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.