Primary experimental recordPositive observation

PMC12858582::ACT035383

TpNPY

Evidence text

Paper-level observation

Fig. 7A-D: SOD activity, MDA and GSH concentration in the glutamate-treated group reduced sharply and GSH concentration increased dramatically, whereas these effects were effectively counteracted by the application of increasing concentration of TpNPY.

textConfidence: medium

Assay observation

Activity

Antioxidant

Subtype

Not reported by source

Measure

qualitative

Comparator

Raw observation

reversed alterations in SOD, MDA, GSH, GSSG caused by glutamate

Normalized measurement

Not reported by source

Value minimum

Not reported by source

Value maximum

Not reported by source

Target

Mus musculus

Assay method

Not reported by source

Sequence

VGGPPKRPESFKSMAELNAYLSDLAGYYTVIGRPRF

Standardization

ready simple

Source publication

A coral-derived neuropeptide suppresses pentylenetetrazol (PTZ)-induced epileptic seizures and improves recognition memory deficits by modulating NPY-Y1R

Archives of Toxicology · 2026

DOI 10.1007/s00204-025-04164-3 PMC12858582

Parent mention

Related peptide identities

PEPDIA-PLP-002974

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.