PepDiana
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Primary experimental recordPositive observation

PMC12830260::ACT034436

TXM-CB3

Evidence text

Paper-level observation

Fig. 5B-D: By week 6, seizure frequency in CB3-treated animals was reduced by more than 60% compared to control group (p < 0.001).
textConfidence: medium

Assay observation

Activity
Other
Subtype
Not reported by source
Measure
other
Comparator
=
Raw observation
reduced by more than 60% compared to control group by week 6 % reduction
Normalized measurement
=60 other
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
ACCPCNH
Standardization
ready simple
Assay conditions
"original_unit=% reduction"

Source publication

Thioredoxin-mimetic peptide attenuates epilepsy progression and neurocognitive deficits

Redox Biology · 2026

DOI 10.1016/j.redox.2026.104021 PMC12830260
Parent mention

Related peptide identities

PEPDIA-PLP-000024

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.