PepDiana
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Primary experimental recordPositive observation

PMC12830260::ACT034417

TXM-CB3

Evidence text

Paper-level observation

Fig. 1E: CB3 pretreatment (100 μM, 2 h) significantly inhibits proinflammatory cytokines TNF-α expression.
textConfidence: medium

Assay observation

Activity
Immunomodulatory
Subtype
Anti-inflammatory
Measure
fold_change
Comparator
=
Raw observation
significantly inhibited TNF-α expression relative mRNA level
Normalized measurement
=100 other
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Rattus norvegicus
Assay method
Not reported by source
Sequence
ACCPCNH
Standardization
ready simple
Assay conditions
"original_unit=relative mRNA level"

Source publication

Thioredoxin-mimetic peptide attenuates epilepsy progression and neurocognitive deficits

Redox Biology · 2026

DOI 10.1016/j.redox.2026.104021 PMC12830260
Parent mention

Related peptide identities

PEPDIA-PLP-000024

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.