PepDiana
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Primary experimental recordPositive observation

PMC12677653::ACT031884

Insig1/2 loop 1 peptide

Evidence text

Paper-level observation

treatment of HCC cells with the peptide inhibited IGF1-induced nuclear translocation of SREBP2 (Figure S2a)
textConfidence: medium

Assay observation

Activity
Metabolic/Cardiovascular
Subtype
Antibacterial
Measure
percent_inhibition
Comparator
=
Raw observation
inhibited
Normalized measurement
Not reported by source
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Homo sapiens
Assay method
Not reported by source
Sequence
LYPCIDSHLGEPHKFKRE
Standardization
ready simple

Source publication

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science · 2025

DOI 10.1002/advs.202508111 PMC12677653
Parent mention

Related peptide identities

PEPDIA-PLP-001956

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.