PepDiana
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Primary experimental recordPositive observation

PMC12677653::ACT031878

Insig1/2 loop 1 peptide

Evidence text

Paper-level observation

semaglutide administration decreased high-fat diet-increased lipid levels ... and this reduction was further promoted by combined treatment with the Insig1/2 loop 1 peptide (Figure 5d)
textConfidence: medium

Assay observation

Activity
Metabolic/Cardiovascular
Subtype
Antibacterial
Measure
percent_inhibition
Comparator
=
Raw observation
reduced
Normalized measurement
=2
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Mus musculus
Assay method
Not reported by source
Sequence
LYPCIDSHLGEPHKFKRE
Standardization
ready simple

Source publication

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science · 2025

DOI 10.1002/advs.202508111 PMC12677653
Parent mention

Related peptide identities

PEPDIA-PLP-001956

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.