PepDiana
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Primary experimental recordNegative / threshold

PMC12677653::ACT031870

Insig1/2 loop 1 peptide

Evidence text

Paper-level observation

Intravenous injection of the LNPs with the Insig1/2 loop 1 peptide into mice did not result in obvious adverse effects, as revealed by ... H&E staining ... and blood examination (Figure S4c-k)
textConfidence: medium

Assay observation

Activity
Toxicity
Subtype
General Toxic
Measure
qualitative
Comparator
=
Raw observation
no obvious adverse effects
Normalized measurement
=2
Value minimum
Not reported by source
Value maximum
Not reported by source
Target
Mus musculus
Assay method
Not reported by source
Sequence
LYPCIDSHLGEPHKFKRE
Standardization
ready simple

Source publication

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science · 2025

DOI 10.1002/advs.202508111 PMC12677653
Parent mention

Related peptide identities

PEPDIA-PLP-001956

Release PepDiana-V1-20260620. The stable record URL can be cited directly in supplementary material and downstream analyses.